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Association details:
Biomarker:
No biomarker
Cancer:
Liposarcoma
Drug:
Halaven (eribulin mesylate)
(
Microtubule inhibitor
,
CBP inhibitor
,
β-catenin inhibitor
)
Direction:
Sensitive
Evidence:
Evidence Level:
Sensitive: A1 - Approval
Source:
FDA
Published date:
10/19/2016
Excerpt:
HALAVEN is a microtubule inhibitor indicated for the treatment of patients with...Unresectable or metastatic liposarcoma who have received a prior anthracycline-containing regimen.
Evidence Level:
Sensitive: A1 - Approval
Source:
European Medicines Agency
Published date:
03/17/2011
Excerpt:
Halaven is indicated for the treatment of adult patients with unresectable liposarcoma…
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
NCCN
Excerpt:
Soft Tissue Sarcoma: Preferred Regimens…Eribulin (category 1 recommendation for liposarcoma, category 2A for other subtypes)
Evidence Level:
Sensitive: A2 - Guideline
New
Source:
ESMO.org
Title:
Soft tissue and visceral sarcomas: ESMO–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up†
Excerpt:
Summary of recommendations...Eribulin is an option in patients with liposarcomas and LMS [II, A].
DOI:
10.1093/annonc/mdy310
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