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BIOMARKER:

FLT3-ITD mutation + IDH2 mutation

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Entrez ID:

Related biomarkers:

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FLT3-ITD mutation (90)

IDH2 mutation (70)

FLT3 mutation (67)

FLT3-TKD mutation (13)

FLT3 D835Y (12)

FLT3 F691L (11)

FLT3-ITD mutation + FLT3-TKD mutation (5)

DNMT3A mutation + FLT3-ITD mutation (4)

FLT3 mutation + NPM1 mutation (4)

FLT3 N676D + FLT3 Y842C (3)

FLT3 mutation + DNMT3A mutation (3)

FLT3 mutation + NRAS mutation (3)

FLT3 wild-type (3)

FLT3-ITD mutation + FLT3 D835 (3)

FLT3-ITD mutation + MLL rearrangement (3)

FLT3-ITD mutation + NPM1 mutation (3)

FLT3‐ITD + NPM1 mutation (3)

FLT3‐ITD mutation + DNMT3A mutation + NPM1 mutation (3)

IDH wild-type (3)

FLT3 mutation + MLL mutation (2)

FLT3-ITD mutation + FLT3 D835Y (2)

FLT3-ITD mutation + FLT3 F691L (2)

FLT3-ITD mutation + IDH1 mutation (2)

FLT3-ITD mutation + WT1 mutation (2)

CEBPZ rearrangement + FLT3-TKD mutation (1)

FLT3 E588_Y589INSKYFYVDFRE (1)

FLT3 F691L + FLT3 D835F (1)

FLT3 F691L + FLT3 D835H (1)

FLT3 F691L + FLT3 D835V (1)

FLT3 F691L + FLT3 D835Y (1)

FLT3 F691L + FLT3 D839G (1)

FLT3 F691L + FLT3 Y842C (1)

FLT3 NPOS + FLT3 D835N (1)

FLT3 V592A + FLT3 D835N (1)

FLT3 V592_D593INSDFREY (1)

FLT3 Y591_V592INSVDFREYE (1)

FLT3 mutation + IDH1 mutation (1)

FLT3 mutation + NRAS mutation + PTPN11 mutation (1)

FLT3 mutation + PTPN11 mutation (1)

FLT3 positive (1)

FLT3-ITD F692L + NPM1 mutation (1)

FLT3-ITD mutation + ASXL1 mutation (1)

FLT3-ITD mutation + ASXL1 mutation + NRAS mutation (1)

FLT3-ITD mutation + DNMT3A mutation + ASXL1 mutation (1)

FLT3-ITD mutation + DNMT3A mutation + NRAS mutation (1)

FLT3-ITD mutation + FLT3 D835Y + FLT3 F691L (1)

FLT3-ITD mutation + NRAS mutation + GATA2 mutation (1)

FLT3-ITD mutation+ DNMT3A mutation + ASXL1 mutation + NRAS mutation (1)

FLT3‐ITD + DNMT3A mutation (1)

FLT3‐ITD + WT1 mutation (1)

MLL rearrangement + FLT3 mutation (1)

NPM1 mutation + FLT3-ITD mutation + TET2 mutation + CUX1 mutation (1)

NPM1 mutation + FLT3-TKD mutation (1)

NPM1 mutation + SRSF2 mutation + FLT3-ITD mutation+ DNMT3A mutation + ASXL1 mutation + NRAS mutation (1)

DNMT3A mutation + IDH mutation (1)

IDH1 R132C + PIK3CA E545K + IDH2 R172K (1)

IDH2 R140Q + NPM1 mutation (1)

IDH2 R140W + EGFR L858R (1)

IDH2 mutation + NRAS mutation (1)

IDH2 mutation + SRSF2 mutation (1)

IDH2 mutation + TP53 mutation (1)

IDH2 mutation + NPM1 mutation (1)

PIK3CA mutation + TTN mutation + IDH2 mutation (1)

TTN mutation + IDH2 mutation (1)

FLT3 F691L + FLT3 Y842H (0)

FLT3-ITD F692L (0)

IDH mutation + BRAF V600E (0)

IDH mutation + Chr del(1p) + Chr del(19q) (0)

IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)

IDH mutation + Chr del(1p) + Chr del(19q) + NTRK fusion (0)

IDH mutation + NTRK fusion (0)

FLT3-ITD mutation (90)

IDH2 mutation (70)

FLT3 mutation (67)

FLT3-TKD mutation (13)

FLT3 D835Y (12)

FLT3 F691L (11)

FLT3-ITD mutation + FLT3-TKD mutation (5)

DNMT3A mutation + FLT3-ITD mutation (4)

FLT3 mutation + NPM1 mutation (4)

FLT3 N676D + FLT3 Y842C (3)

FLT3 mutation + DNMT3A mutation (3)

FLT3 mutation + NRAS mutation (3)

FLT3 wild-type (3)

FLT3-ITD mutation + FLT3 D835 (3)

FLT3-ITD mutation + MLL rearrangement (3)

FLT3-ITD mutation + NPM1 mutation (3)

FLT3‐ITD + NPM1 mutation (3)

FLT3‐ITD mutation + DNMT3A mutation + NPM1 mutation (3)

IDH wild-type (3)

FLT3 mutation + MLL mutation (2)

FLT3-ITD mutation + FLT3 D835Y (2)

FLT3-ITD mutation + FLT3 F691L (2)

FLT3-ITD mutation + IDH1 mutation (2)

FLT3-ITD mutation + WT1 mutation (2)

CEBPZ rearrangement + FLT3-TKD mutation (1)

FLT3 E588_Y589INSKYFYVDFRE (1)

FLT3 F691L + FLT3 D835F (1)

FLT3 F691L + FLT3 D835H (1)

FLT3 F691L + FLT3 D835V (1)

FLT3 F691L + FLT3 D835Y (1)

FLT3 F691L + FLT3 D839G (1)

FLT3 F691L + FLT3 Y842C (1)

FLT3 NPOS + FLT3 D835N (1)

FLT3 V592A + FLT3 D835N (1)

FLT3 V592_D593INSDFREY (1)

FLT3 Y591_V592INSVDFREYE (1)

FLT3 mutation + IDH1 mutation (1)

FLT3 mutation + NRAS mutation + PTPN11 mutation (1)

FLT3 mutation + PTPN11 mutation (1)

FLT3 positive (1)

FLT3-ITD F692L + NPM1 mutation (1)

FLT3-ITD mutation + ASXL1 mutation (1)

FLT3-ITD mutation + ASXL1 mutation + NRAS mutation (1)

FLT3-ITD mutation + DNMT3A mutation + ASXL1 mutation (1)

FLT3-ITD mutation + DNMT3A mutation + NRAS mutation (1)

FLT3-ITD mutation + FLT3 D835Y + FLT3 F691L (1)

FLT3-ITD mutation + NRAS mutation + GATA2 mutation (1)

FLT3-ITD mutation+ DNMT3A mutation + ASXL1 mutation + NRAS mutation (1)

FLT3‐ITD + DNMT3A mutation (1)

FLT3‐ITD + WT1 mutation (1)

MLL rearrangement + FLT3 mutation (1)

NPM1 mutation + FLT3-ITD mutation + TET2 mutation + CUX1 mutation (1)

NPM1 mutation + FLT3-TKD mutation (1)

NPM1 mutation + SRSF2 mutation + FLT3-ITD mutation+ DNMT3A mutation + ASXL1 mutation + NRAS mutation (1)

DNMT3A mutation + IDH mutation (1)

IDH1 R132C + PIK3CA E545K + IDH2 R172K (1)

IDH2 R140Q + NPM1 mutation (1)

IDH2 R140W + EGFR L858R (1)

IDH2 mutation + NRAS mutation (1)

IDH2 mutation + SRSF2 mutation (1)

IDH2 mutation + TP53 mutation (1)

IDH2 mutation + NPM1 mutation (1)

PIK3CA mutation + TTN mutation + IDH2 mutation (1)

TTN mutation + IDH2 mutation (1)

FLT3 F691L + FLT3 Y842H (0)

FLT3-ITD F692L (0)

IDH mutation + BRAF V600E (0)

IDH mutation + Chr del(1p) + Chr del(19q) (0)

IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)

IDH mutation + Chr del(1p) + Chr del(19q) + NTRK fusion (0)

IDH mutation + NTRK fusion (0)

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FLT3-ITD mutation + IDH2 mutation	Acute Myelogenous Leukemia	FLT3-ITD mutation + IDH2 mutation	Acute Myelogenous Leukemia	FLT3 inhibitor Sensitive: C3 – Early Trials FLT3 inhibitor Sensitive : C3	FLT3 inhibitor Sensitive: C3 – Early Trials FLT3 inhibitor Sensitive : C3
FLT3-ITD mutation + IDH2 mutation	Acute Myelogenous Leukemia	FLT3-ITD mutation + IDH2 mutation	Acute Myelogenous Leukemia	IDH2 inhibitor Sensitive: C3 – Early Trials IDH2 inhibitor Sensitive : C3	IDH2 inhibitor Sensitive: C3 – Early Trials IDH2 inhibitor Sensitive : C3