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BIOMARKER:

FLT3-ITD mutation + MLL rearrangement

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Other names: FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2, HTRX1, HTRX, MLL1A, Mixed Lineage Leukemia 1, Myeloid/Lymphoid Or Mixed-Lineage Leukemia Protein 1, CXXC7, MLL1, TRX1, Zinc Finger Protein HRX, Trithorax-Like Protein, ALL-1, Lysine (K)-Specific Methyltransferase 2A, CXXC-Type Zinc Finger Protein 7, Histone-Lysine N-Meth
Entrez ID:
FLT3-ITD mutation + MLL rearrangement
AML
gilteritinib + MI-503
Sensitive: D – Preclinical
FLT3-ITD mutation + MLL rearrangement
AML
ARO-002 + MI-503
Sensitive: D – Preclinical
FLT3-ITD mutation + MLL rearrangement
AML
quizartinib + MI-503
Sensitive: D – Preclinical