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BIOMARKER:
FLT3-ITD mutation + FLT3-TKD mutation
i
Other names:
FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
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Entrez ID:
2322
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
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FLT3-ITD mutation + FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation + FLT3-TKD mutation
Acute Myelogenous Leukemia
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
gilteritinib
Sensitive: B - Late Trials
gilteritinib
Sensitive
:
B
FLT3-ITD mutation + FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation + FLT3-TKD mutation
Acute Myelogenous Leukemia
venetoclax + gilteritinib
Sensitive: C3 – Early Trials
venetoclax + gilteritinib
Sensitive
:
C3
venetoclax + gilteritinib
Sensitive: C3 – Early Trials
venetoclax + gilteritinib
Sensitive
:
C3
FLT3-ITD mutation + FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation + FLT3-TKD mutation
Acute Myelogenous Leukemia
sorafenib + gilteritinib
Sensitive: C3 – Early Trials
sorafenib + gilteritinib
Sensitive
:
C3
sorafenib + gilteritinib
Sensitive: C3 – Early Trials
sorafenib + gilteritinib
Sensitive
:
C3
FLT3-ITD mutation + FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation + FLT3-TKD mutation
Acute Myelogenous Leukemia
ARO-002
Sensitive: C3 – Early Trials
ARO-002
Sensitive
:
C3
ARO-002
Sensitive: C3 – Early Trials
ARO-002
Sensitive
:
C3
FLT3-ITD mutation + FLT3-TKD mutation
Acute Myelogenous Leukemia
FLT3-ITD mutation + FLT3-TKD mutation
Acute Myelogenous Leukemia
quizartinib
Resistant: C4 – Case Studies
quizartinib
Resistant
:
C4
quizartinib
Resistant: C4 – Case Studies
quizartinib
Resistant
:
C4
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