^
    BIOMARKER:

    FLT3 mutation + NPM1 mutation

    i
    Other names: Nucleophosmin (Nucleolar Phosphoprotein B23, Numatrin), Testicular Tissue Protein Li 128, Nucleolar Protein NO38, Numatrin, NPM1, Nucleophosmin 1, Nucleophosmin/Nucleoplasmin Family, Member 1, Nucleolar Phosphoprotein B23, FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
    Entrez ID:
    2322; 4869
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others
    FLT3 mutation + NPM1 mutation
    AML
    gilteritinib
    Sensitive: C3 – Early Trials
    FLT3 mutation + NPM1 mutation
    AML
    ivosidenib
    Resistant: C3 – Early Trials
    FLT3 mutation + NPM1 mutation
    AML
    CB-659
    Sensitive: D – Preclinical
    FLT3 mutation + NPM1 mutation
    AML
    ixazomib
    Resistant: D – Preclinical