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BIOMARKER:

IDH2 mutation

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Other names: IDH2, Isocitrate Dehydrogenase (NADP(+)) 2, Isocitrate Dehydrogenase (NADP(+)) 2, Mitochondrial, Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial, Isocitrate Dehydrogenase [NADP], Mitochondrial, Oxalosuccinate Decarboxylase, NADP(+)-Specific ICDH, ICD-M, IDH, IDP, MNADP-IDH, D2HGA2, IDHM, IDPM
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Entrez ID:
Related biomarkers:
IDH2 mutation
Acute Myelogenous Leukemia
enasidenib
Sensitive
:
A1
IDH2 mutation
Acute Myelogenous Leukemia
venetoclax
Sensitive
:
A2
IDH2 mutation
Astrocytoma
cisplatin
Sensitive
:
A2
IDH2 mutation
Astrocytoma
carboplatin
Sensitive
:
A2
IDH2 mutation
Astrocytoma
etoposide IV
Sensitive
:
A2
IDH2 mutation
Astrocytoma
bevacizumab
Sensitive
:
A2
IDH2 mutation
Astrocytoma
carmustine
Sensitive
:
A2
IDH2 mutation
Astrocytoma
lomustine
Sensitive
:
A2
IDH2 mutation
Astrocytoma
PCV
Sensitive
:
A2
IDH2 mutation
Astrocytoma
temozolomide
Sensitive
:
A2
IDH2 mutation
Acute Myelogenous Leukemia
cytarabine
Resistant
:
B
IDH2 mutation
Glioma
temozolomide
Sensitive
:
B
IDH2 mutation
Glioma
temozolomide gel
Sensitive
:
B
IDH2 mutation
Glioma
PCV
Sensitive
:
B
IDH2 mutation
Acute Lymphocytic Leukemia
enasidenib
Sensitive
:
B
IDH2 mutation
Glioma
pamiparib
Sensitive
:
C2
IDH2 mutation
Cholangiocarcinoma
dasatinib
Sensitive
:
C2
IDH2 mutation
Myelodysplastic Syndrome
enasidenib
Sensitive
:
C2
IDH2 mutation
Acute Myelogenous Leukemia
MEN1703
Sensitive
:
C2
IDH2 mutation
Glioma
S095032
Sensitive
:
C2
IDH2 mutation
Glioma
TG02
Sensitive
:
C3
IDH2 mutation
Acute Myelogenous Leukemia
cytarabine / daunorubicin liposomal formulation
Sensitive
:
C3
IDH2 mutation
Acute Myelogenous Leukemia
venetoclax + enasidenib
Sensitive
:
C3
IDH2 mutation
Acute Myelogenous Leukemia
venetoclax + RO5503781
Sensitive
:
C3
IDH2 mutation
Peripheral T-cell Lymphoma
copanlisib
Sensitive
:
C3
IDH2 mutation
Chronic Myelomonocytic Leukemia
venetoclax
Sensitive
:
C3
IDH2 mutation
Acute Myelogenous Leukemia
venetoclax + ABBV-621
Sensitive
:
C3
IDH2 mutation
Acute Myelogenous Leukemia
CFI-400945
Sensitive
:
C3
IDH2 mutation
Acute Myelogenous Leukemia
venetoclax + midostaurin
Resistant
:
C3
IDH2 mutation
Acute Myelogenous Leukemia
venetoclax + gilteritinib
Resistant
:
C3
IDH2 mutation
Acute Myelogenous Leukemia
venetoclax + sorafenib
Resistant
:
C3
IDH2 mutation
Glioblastoma
temozolomide gel
Sensitive
:
C3