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BIOMARKER:

FLT3 mutation

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Other names: FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
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Entrez ID:
FLT3 mutation
Acute Myelogenous Leukemia
gilteritinib
Sensitive
:
A1
SOHO 2022 - 1 week - (New C3)
FLT3 mutation
Acute Myelogenous Leukemia
venetoclax
Sensitive
:
A2
SOHO 2022 - 1 week - (New C3)
FLT3 mutation
Acute Myelogenous Leukemia
midostaurin
Sensitive
:
A1
FLT3 mutation
Acute Myelogenous Leukemia
gemtuzumab ozogamicin
Sensitive
:
A2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 inhibitor
Sensitive
:
B
FLT3 mutation
Acute Myelogenous Leukemia
venetoclax + azacitidine
Sensitive
:
B
FLT3 mutation
Leukemia
midostaurin
Sensitive
:
B
FLT3 mutation
Acute Myelogenous Leukemia
HM43239
Sensitive
:
B
FLT3 mutation
Acute Myelogenous Leukemia
quizartinib + RAIN-32
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
sunitinib
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
quizartinib
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
Hypomethylating agent + venetoclax
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
ARO-002
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
CEP-701
Sensitive
:
C2
FLT3 mutation
Myelodysplastic Syndrome
ARO-002
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
sorafenib
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
azacitidine
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 inhibitor + gilteritinib
Sensitive
:
C2
FLT3 mutation
Myelodysplastic Syndrome
quizartinib
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
venetoclax + midostaurin
Sensitive
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
venetoclax + gilteritinib
Sensitive
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
venetoclax + sorafenib
Sensitive
:
C3
FLT3 mutation
Non Small Cell Lung Cancer
nintedanib
Sensitive
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
ivosidenib
Resistant
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
cytarabine + clofarabine
Sensitive
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
cytarabine + cladribine
Sensitive
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
decitabine + clofarabine
Sensitive
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
decitabine + cladribine
Sensitive
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 inhibitor + venetoclax + decitabine
Sensitive
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
midostaurin + gemtuzumab ozogamicin
Sensitive
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
CA-4948
Sensitive
:
C3
FLT3 mutation
Myelodysplastic Syndrome
CA-4948
Sensitive
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
midostaurin + cytarabine / daunorubicin liposomal formulation
Sensitive
:
C3
FLT3 mutation
Acute Myelogenous Leukemia
cytarabine / daunorubicin liposomal formulation
Sensitive
:
C4