^
BIOMARKER:
FLT3 mutation
i
Other names: FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
Entrez ID:
FLT3 mutation
AML
gilteritinib
Sensitive
:
A1
FLT3 mutation
AML
midostaurin
Sensitive
:
A1
FLT3 mutation
AML
venetoclax
Sensitive
:
A2
FLT3 mutation
AML
FLT3 inhibitor
Sensitive
:
B
FLT3 mutation
AML
sunitinib
Sensitive
:
C2
FLT3 mutation
AML
quizartinib
Sensitive
:
C2
FLT3 mutation
AML
Hypomethylating agent + venetoclax
Sensitive
:
C2
FLT3 mutation
AML
ARO-002
Sensitive
:
C2
FLT3 mutation
AML
CEP-701
Sensitive
:
C2
FLT3 mutation
MDS
ARO-002
Sensitive
:
C2
FLT3 mutation
AML
sorafenib
Sensitive
:
C2
FLT3 mutation
AML
venetoclax + midostaurin
Sensitive
:
C3
FLT3 mutation
AML
venetoclax + gilteritinib
Sensitive
:
C3
FLT3 mutation
AML
venetoclax + sorafenib
Sensitive
:
C3
FLT3 mutation
NSCLC
nintedanib
Sensitive
:
C3
FLT3 mutation
AML
ivosidenib
Resistant
:
C3
FLT3 mutation
AML
quizartinib + RAIN-32
Sensitive
:
D
FLT3 mutation
AML
MEK inhibitor + FLT3 inhibitor
Sensitive
:
D
FLT3 mutation
AML
sorafenib + LY3009120
Sensitive
:
D
FLT3 mutation
AML
PF-02545920
Sensitive
:
D
FLT3 mutation
AML
5-fluorouracil
Sensitive
:
D
FLT3 mutation
AML
quizartinib + IACS-010759
Sensitive
:
D
FLT3 mutation
AML
AG-1296
Sensitive
:
D
FLT3 mutation
CML
sunitinib
Sensitive
:
D
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