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BIOMARKER:
FLT3 mutation
i
Other names:
FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
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Entrez ID:
2322
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
›
Related tests:
LeukoStrat® CDx FLT3 Mutation Assay (6)
LeukoStrat® CDx FLT3 Mutation Assay (6)
Associations
News
Trials
VERI cancer hierarchy
Reset Filters
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
gilteritinib
Sensitive: A1 - Approval
gilteritinib
Sensitive
:
A1
gilteritinib
Sensitive: A1 - Approval
gilteritinib
Sensitive
:
A1
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
midostaurin
Sensitive: A1 - Approval
midostaurin
Sensitive
:
A1
midostaurin
Sensitive: A1 - Approval
midostaurin
Sensitive
:
A1
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
venetoclax
Sensitive: A2 - Guideline
venetoclax
Sensitive
:
A2
venetoclax
Sensitive: A2 - Guideline
venetoclax
Sensitive
:
A2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
gemtuzumab ozogamicin
Sensitive: A2 - Guideline
gemtuzumab ozogamicin
Sensitive
:
A2
gemtuzumab ozogamicin
Sensitive: A2 - Guideline
gemtuzumab ozogamicin
Sensitive
:
A2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 inhibitor
Sensitive: B - Late Trials
FLT3 inhibitor
Sensitive
:
B
FLT3 inhibitor
Sensitive: B - Late Trials
FLT3 inhibitor
Sensitive
:
B
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
venetoclax + azacitidine
Sensitive: B - Late Trials
venetoclax + azacitidine
Sensitive
:
B
venetoclax + azacitidine
Sensitive: B - Late Trials
venetoclax + azacitidine
Sensitive
:
B
FLT3 mutation
Leukemia
FLT3 mutation
Leukemia
midostaurin
Sensitive: B - Late Trials
midostaurin
Sensitive
:
B
midostaurin
Sensitive: B - Late Trials
midostaurin
Sensitive
:
B
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
azacitidine
Sensitive: B - Late Trials
azacitidine
Sensitive
:
B
azacitidine
Sensitive: B - Late Trials
azacitidine
Sensitive
:
B
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
HM43239
Sensitive: B - Late Trials
HM43239
Sensitive
:
B
HM43239
Sensitive: B - Late Trials
HM43239
Sensitive
:
B
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
quizartinib + RAIN-32
Sensitive: C2 – Inclusion Criteria
quizartinib + RAIN-32
Sensitive
:
C2
quizartinib + RAIN-32
Sensitive: C2 – Inclusion Criteria
quizartinib + RAIN-32
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
sunitinib
Sensitive: C2 – Inclusion Criteria
sunitinib
Sensitive
:
C2
sunitinib
Sensitive: C2 – Inclusion Criteria
sunitinib
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
quizartinib
Sensitive: C2 – Inclusion Criteria
quizartinib
Sensitive
:
C2
quizartinib
Sensitive: C2 – Inclusion Criteria
quizartinib
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
Hypomethylating agent + venetoclax
Sensitive: C2 – Inclusion Criteria
Hypomethylating agent + venetoclax
Sensitive
:
C2
Hypomethylating agent + venetoclax
Sensitive: C2 – Inclusion Criteria
Hypomethylating agent + venetoclax
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
venetoclax + gilteritinib
Sensitive: C2 – Inclusion Criteria
venetoclax + gilteritinib
Sensitive
:
C2
venetoclax + gilteritinib
Sensitive: C2 – Inclusion Criteria
venetoclax + gilteritinib
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
ARO-002
Sensitive: C2 – Inclusion Criteria
ARO-002
Sensitive
:
C2
ARO-002
Sensitive: C2 – Inclusion Criteria
ARO-002
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
CEP-701
Sensitive: C2 – Inclusion Criteria
CEP-701
Sensitive
:
C2
CEP-701
Sensitive: C2 – Inclusion Criteria
CEP-701
Sensitive
:
C2
FLT3 mutation
Myelodysplastic Syndrome
FLT3 mutation
Myelodysplastic Syndrome
ARO-002
Sensitive: C2 – Inclusion Criteria
ARO-002
Sensitive
:
C2
ARO-002
Sensitive: C2 – Inclusion Criteria
ARO-002
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
sorafenib
Sensitive: C2 – Inclusion Criteria
sorafenib
Sensitive
:
C2
sorafenib
Sensitive: C2 – Inclusion Criteria
sorafenib
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 inhibitor + gilteritinib
Sensitive: C2 – Inclusion Criteria
FLT3 inhibitor + gilteritinib
Sensitive
:
C2
FLT3 inhibitor + gilteritinib
Sensitive: C2 – Inclusion Criteria
FLT3 inhibitor + gilteritinib
Sensitive
:
C2
FLT3 mutation
Myelodysplastic Syndrome
FLT3 mutation
Myelodysplastic Syndrome
quizartinib
Sensitive: C2 – Inclusion Criteria
quizartinib
Sensitive
:
C2
quizartinib
Sensitive: C2 – Inclusion Criteria
quizartinib
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
CA-4948
Sensitive: C2 – Inclusion Criteria
CA-4948
Sensitive
:
C2
CA-4948
Sensitive: C2 – Inclusion Criteria
CA-4948
Sensitive
:
C2
FLT3 mutation
Myelodysplastic Syndrome
FLT3 mutation
Myelodysplastic Syndrome
CA-4948
Sensitive: C2 – Inclusion Criteria
CA-4948
Sensitive
:
C2
CA-4948
Sensitive: C2 – Inclusion Criteria
CA-4948
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
azacitidine
Sensitive: C2 – Inclusion Criteria
azacitidine
Sensitive
:
C2
azacitidine
Sensitive: C2 – Inclusion Criteria
azacitidine
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
azacitidine
Sensitive: C2 – Inclusion Criteria
azacitidine
Sensitive
:
C2
azacitidine
Sensitive: C2 – Inclusion Criteria
azacitidine
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
azacitidine
Sensitive: C2 – Inclusion Criteria
azacitidine
Sensitive
:
C2
azacitidine
Sensitive: C2 – Inclusion Criteria
azacitidine
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
ORY-1001
Sensitive: C2 – Inclusion Criteria
ORY-1001
Sensitive
:
C2
ORY-1001
Sensitive: C2 – Inclusion Criteria
ORY-1001
Sensitive
:
C2
FLT3 mutation
Leukemia
FLT3 mutation
Leukemia
venetoclax + gilteritinib
Sensitive: C2 – Inclusion Criteria
venetoclax + gilteritinib
Sensitive
:
C2
venetoclax + gilteritinib
Sensitive: C2 – Inclusion Criteria
venetoclax + gilteritinib
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
GS-9876
Sensitive: C2 – Inclusion Criteria
GS-9876
Sensitive
:
C2
GS-9876
Sensitive: C2 – Inclusion Criteria
GS-9876
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
GS-9973
Sensitive: C2 – Inclusion Criteria
GS-9973
Sensitive
:
C2
GS-9973
Sensitive: C2 – Inclusion Criteria
GS-9973
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
STI-8591
Sensitive: C2 – Inclusion Criteria
STI-8591
Sensitive
:
C2
STI-8591
Sensitive: C2 – Inclusion Criteria
STI-8591
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
cytarabine + midostaurin
Sensitive: C2 – Inclusion Criteria
cytarabine + midostaurin
Sensitive
:
C2
cytarabine + midostaurin
Sensitive: C2 – Inclusion Criteria
cytarabine + midostaurin
Sensitive
:
C2
FLT3 mutation
Acute Myelogenous Leukemia
FLT3 mutation
Acute Myelogenous Leukemia
venetoclax + midostaurin
Sensitive: C3 – Early Trials
venetoclax + midostaurin
Sensitive
:
C3
venetoclax + midostaurin
Sensitive: C3 – Early Trials
venetoclax + midostaurin
Sensitive
:
C3
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