^
    BIOMARKER:

    FLT3 N676D + FLT3 Y842C

    i
    Other names: FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
    Entrez ID:
    2322
    Related biomarkers:
    Expression
    Mutation
    CNA
    Fusion
    Others

    Associations

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    Trials
    FLT3 N676D + FLT3 Y842C
    AML
    sorafenib
    Resistant: D – Preclinical
    FLT3 N676D + FLT3 Y842C
    AML
    quizartinib
    Resistant: D – Preclinical
    FLT3 N676D + FLT3 Y842C
    AML
    sorafenib + ARO-002
    Sensitive: D – Preclinical