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BIOMARKER:

FLT3-ITD mutation + FLT3 D835

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Other names: FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
Entrez ID:
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Trials
FLT3-ITD mutation + FLT3 D835
AML
gilteritinib
Sensitive: C3 – Early Trials
FLT3-ITD mutation + FLT3 D835
AML
CPI-0610
Sensitive: D – Preclinical
FLT3-ITD mutation + FLT3 D835
AML
venetoclax + gilteritinib
Sensitive: D – Preclinical