^
BIOMARKER:

FLT3 D835Y

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Other names: FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
Entrez ID:
FLT3 D835Y
AML
midostaurin
Sensitive: C2 – Inclusion Criteria
FLT3 D835Y
AML
quizartinib
Resistant: C3 – Early Trials
FLT3 D835Y
AML
sunitinib
Resistant: C3 – Early Trials
FLT3 D835Y
AML
sorafenib
Resistant: C3 – Early Trials
FLT3 D835Y
AML
imatinib
Sensitive: C4 – Case Studies
FLT3 D835Y
AML
pexidartinib
Sensitive: C4 – Case Studies
FLT3 D835Y
AML
Max-40279
Sensitive: D – Preclinical
FLT3 D835Y
AML
ponatinib
Resistant: D – Preclinical
FLT3 D835Y
AML
gilteritinib
Sensitive: D – Preclinical
FLT3 D835Y
AML
MLN518
Resistant: D – Preclinical
FLT3 D835Y
AML
SU5614
Sensitive: D – Preclinical