^
BIOMARKER:

FLT3-TKD mutation

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Other names: FLT3, Fms Related Tyrosine Kinase 3, Receptor-Type Tyrosine-Protein Kinase FLT3, Stem Cell Tyrosine Kinase 1, Fms-Like Tyrosine Kinase 3, CD135, FLK-2, STK1, Growth Factor Receptor Tyrosine Kinase Type III, Fetal Liver Kinase 2
Entrez ID:
FLT3-TKD mutation
AML
midostaurin
Sensitive: A2 - Guideline
FLT3-TKD mutation
AML
gilteritinib
Sensitive: A2 - Guideline
FLT3-TKD mutation
AML
cytarabine + midostaurin + daunorubicin
Sensitive: A2 - Guideline
FLT3-TKD mutation
AML
venetoclax + azacitidine
Sensitive: B - Late Trials
FLT3-TKD mutation
AML
LY3009120
Sensitive: C3 – Early Trials
FLT3-TKD mutation
AML
venetoclax + gilteritinib
Sensitive: C3 – Early Trials
FLT3-TKD mutation
AML
venetoclax
Sensitive: C3 – Early Trials
FLT3-TKD mutation
AML
sorafenib + gilteritinib
Sensitive: C3 – Early Trials
FLT3-TKD mutation
AML
JRF104
Sensitive: D – Preclinical
FLT3-TKD mutation
AML
PHI-101
Sensitive: D – Preclinical