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TEST:
Oncomine™ TCR Pan-Clonality Assay

Type:
Laboratory Developed Test
Related tests:
Evidence

News

1year
Adoptively Infused Memory-like Natural Killer Cells Impact Adaptive Immune Responses in Patients with Acute Myeloid Leukemia (ASH 2023)
Patients were lymphodepleted with fludarabine and cyclophosphamide...Multi-modal analyses of WU-NK-101 highlight unique transcriptional and functional states, which could underpin in vivo potency and persistence. WU-NK-101 are currently being evaluated in a phase 1 study of R/R AML (#NCT05470140).
Clinical • PARP Biomarker • IO biomarker
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CD8 (cluster of differentiation 8) • LAG3 (Lymphocyte Activating 3) • CD276 (CD276 Molecule) • HAVCR2 (Hepatitis A Virus Cellular Receptor 2) • CD34 (CD34 molecule) • PARP1 (Poly(ADP-Ribose) Polymerase 1) • NCAM1 (Neural cell adhesion molecule 1) • STING (stimulator of interferon response cGAMP interactor 1) • IL18 (Interleukin 18) • CD7 (CD7 Molecule) • IL15 (Interleukin 15) • TRB (T Cell Receptor Beta Locus)
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nCounter® PanCancer IO 360™ Panel • Oncomine™ TCR Pan-Clonality Assay
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cyclophosphamide • fludarabine IV • WU-NK-101