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Oncomine™ BCR IGH-SR Assay

Laboratory Developed Test
Related tests:


The Oncomine BCR IGH-SR Assay, RNA, is a robust, targeted next-generation sequencing (NGS) assay designed for hematology-oncology and minimal residual disease (MRD) monitoring research, pharmacodynamics and biomarker analysis of immunotherapy, as well as infectious and autoimmune disease research. The assay accurately identifies and measures clonal expansion of B lymphocytes using total RNA from bone marrow, whole blood, peripheral blood leukocytes (PBLs), peripheral blood mononuclear cells (PBMCs), and fresh-frozen and formalin-fixed paraffin-embedded (FFPE) research samples. The assay identifies unique B-cell clones through targeting of the highly diverse complementarity-determining region 3 (CDR3) of the B-cell receptor IGH chain from mRNA template via AmpliSeq multiplex framework 3 and joining gene primers.
Acute Myelogenous Leukemia, Leukemia
Next-Generation Sequencing (NGS)