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our Premium Content: News alerts, weekly reports and conference plannersTEST:Oncomine™ Breast cfDNA Assay
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News alerts, weekly reports and conference planners
Company:
Thermo Fisher ScientificType:
Laboratory Developed Test
Related tests:
The Oncomine™ Breast cfDNA Assay is part of a complete solution to detect breast tumor-derived DNA (ctDNA) in cell-free DNA (cfDNA). It provides the reagents for library construction and a single pool of multiplex PCR primers for preparation of amplicon libraries from cfDNA obtained from the plasma fraction of a single tube of whole blood. The assay enables the analysis of single nucleotide variants and short indels that are frequently mutated in breast cancer. Ten genes with >150 hotspots are covered (Genes: AKT1, EGFR, ERBB2, ERBB3, ESR1, FBXW7, KRAS, PIK3CA, SF3B1, TP53).
Cancer:
Breast Cancer
Gene:
AKT1 (V-akt murine thymoma viral oncogene homolog 1), EGFR (Epidermal growth factor receptor), ER (Estrogen receptor), ERBB3 (V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3), FBXW7 (F-Box And WD Repeat Domain Containing 7), HER-2 (Human epidermal growth factor receptor 2)
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AKT1 (V-akt murine thymoma viral oncogene homolog 1), EGFR (Epidermal growth factor receptor), ER (Estrogen receptor), ERBB3 (V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3), FBXW7 (F-Box And WD Repeat Domain Containing 7), HER-2 (Human epidermal growth factor receptor 2), KRAS (KRAS proto-oncogene GTPase), PIK3CA (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha), SF3B1 (Splicing Factor 3b Subunit 1), TP53 (Tumor protein P53)
Method:
PCR
