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TEST:
OncoScan™ CNV Assay

Type:
Laboratory Developed Test
Related tests:

Details

Evidence
The OncoScan CNV Assay is a whole-genome copy number microarray-based assay that enables the detection of relevant copy number variations (CNVs) such as copy number gain and loss, loss of heterozygosity (LOH), copy neutral loss of heterozygosity (cnLOH), ploidy, allele specific changes, break point determination, mosaicism, clonal heterogeneity, and chromothripsis. Demonstrated concordance with FISH-confirmed amplifications in key cancer genes including ERBB2 (Her2), EGFR, MDM2, MYC, and FGFR1.
Gene:
EGFR (Epidermal growth factor receptor), FGFR1 (Fibroblast growth factor receptor 1), HER-2 (Human epidermal growth factor receptor 2), MDM2 (E3 ubiquitin protein ligase), MYC (V-myc avian myelocytomatosis viral oncogene homolog)
Method:
MicroArray