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TEST:
Oncomine Myeloid Research Assay

Type:
Laboratory Developed Test
Related tests:

Details

Evidence
The Ion Torrent Oncomine Myeloid Research Assay is a comprehensive, targeted NGS assay designed to assist in the understanding of myeloid cancer. Specifically, it interrogates relevant DNA mutations and fusion transcripts associated with myeloid disorders in a quick and easy NGS run. The panel is comprised of 40 key DNA target genes and 29 driver genes in a broad fusion panel to cover all the major myeloid disorders: acute myeloid leukemia (AML), myeloid dysplastic syndrome (MDS), myeloproliferative neoplasms (MPN), chronic myeloid leukemia (CML), chronic myelomonocytic leukemia (CMML), and juvenile myelomonocytic leukemia (JMML).
Cancer:
Acute Myelogenous Leukemia, Chronic Myeloid Leukemia, Chronic Myelomonocytic Leukemia, Juvenile Myelomonocytic Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm
Gene:
ABL1 (ABL proto-oncogene 1), BRAF (B-raf proto-oncogene), CBL (Cbl proto-oncogene), KRAS (KRAS proto-oncogene GTPase), MPL (MPL Proto-Oncogene, Thrombopoietin Receptor), MYD88 (MYD88 Innate Immune Signal Transduction Adaptor)
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Method:
Next-Generation Sequencing (NGS)