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TEST:
Oncomine™ IGH FR1-J Assay

Type:
Laboratory Developed Test
Related tests:
Evidence

News

over2years
Somatic hypermutation analysis of chronic lymphocytic leukemia research samples by IGH chain next-generation sequencing (AACR 2022)
Concordant results were shown between FR1 and Leader-targeting primers using DNA input showing the utility in both priming locations. Orthogonal testing of the Leader-J assay showed excellent concordance for mutation rate, SHM status, and stereotypy.
Next-generation sequencing
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IGH (Immunoglobulin Heavy Locus)
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Oncomine™ BCR IGH-LR Assay • Oncomine™ BCR IGHV Leader-J Assay • Oncomine™ IGH FR1-J Assay