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    TEST:
    Oncomine™ BCR IGHV Leader-J Assay

    Company:
    Thermo Fisher Scientific
    Type:
    Laboratory Developed Test
    Related tests:
    Details
    Evidence

    News

    over2years
    Somatic hypermutation analysis of chronic lymphocytic leukemia research samples by IGH chain next-generation sequencing (AACR 2022)
    Concordant results were shown between FR1 and Leader-targeting primers using DNA input showing the utility in both priming locations. Orthogonal testing of the Leader-J assay showed excellent concordance for mutation rate, SHM status, and stereotypy.
    Next-generation sequencing
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    IGH (Immunoglobulin Heavy Locus)
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    Oncomine™ BCR IGH-LR Assay • Oncomine™ BCR IGHV Leader-J Assay • Oncomine™ IGH FR1-J Assay