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The FusionPlex Heme v2 panel is an ribonucleic acid (RNA)-based targeted next-generation sequencing (NGS) product that detects and identifies fusions of 87 genes associated with hematological malignancies. Using proprietary Anchored Multiplex PCR (AMP™) -based enrichment, fusions of all genes in this panel can be identified in a single sequencing assay, even without prior knowledge of fusion partners or breakpoints. Additionally, select genes are targeted for molecular barcode-enabled relative expression level detection and point mutation coverage.
Method:
Next-Generation Sequencing (NGS)