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our Premium Content: News alerts, weekly reports and conference plannersTEST:Archer® FusionPlex® Sarcoma kit
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Company:
Integrated DNA TechnologiesType:
Laboratory Developed Test
Related tests:
The Archer® FusionPlex® Sarcoma kit is a targeted sequencing assay to simultaneously detect and identify fusions of 26 genes associated with soft tissue cancers. Studies are performed from RNA extracted from several types of sample (fresh frozen or FFPE). Using Archer’s proprietary Anchored Multiplex PCR (AMP™)-based enrichment, fusions of all genes in this kit can be identified in a single sequencing assay, even without prior knowledge of fusion partners or breakpoints. Archer Analysis software allows the analysis and interpretation of the NGS data.
Cancer:
Sarcoma
Gene:
ALK (Anaplastic lymphoma kinase), EWSR1 (EWS RNA Binding Protein 1), FOXO1 (Forkhead box O1), FUS (FUS RNA Binding Protein), GLI1 (GLI Family Zinc Finger 1), HMGA2 (High mobility group AT-hook 2)
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ALK (Anaplastic lymphoma kinase), EWSR1 (EWS RNA Binding Protein 1), FOXO1 (Forkhead box O1), FUS (FUS RNA Binding Protein), GLI1 (GLI Family Zinc Finger 1), HMGA2 (High mobility group AT-hook 2), JAZF1 (JAZF Zinc Finger 1), NTRK3 (Neurotrophic tyrosine kinase, receptor, type 3), PDGFB (Platelet Derived Growth Factor Subunit B), ROS1 (Proto-Oncogene Tyrosine-Protein Kinase ROS), SS18 (SS18 Subunit Of BAF Chromatin Remodeling Complex), STAT6 (Signal transducer and activator of transcription 6), TAF15 (TATA-Box Binding Protein Associated Factor 15), TFE3 (Transcription Factor Binding To IGHM Enhancer 3), TFG (Trafficking From ER To Golgi Regulator), YWHAE (Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon)
Method:
Next-Generation Sequencing (NGS)
