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DRUG:

BC3448

i
Other names: BC3448
Associations
Trials
Company:
Wuxi Biocity
Drug class:
EGFR inhibitor, CD3 agonist
Related drugs:
Associations
Trials
over1year
A Novel Anti-EGFR/CD3 Bispecific Antibody Exhibits Potent Efficacy for Osimertinib-resistant NSCLC (IASLC-WCLC 2023)
Additionally, the total protein of H1975-OR treated with BC3448 or Panitumumab for 2 days was subsequently subjected for Sally Sue Simple Western analysis. BC3448 exhibited potent antitumor effect in vitro and in vivo and might be a BC3448 exhibited potent antitumor effect in vitro and in vivo and might be a promising agent for Osimertinib-resistant NSCLC.
Clinical • PD(L)-1 Biomarker • IO biomarker
|
JAK2 (Janus kinase 2) • CD8 (cluster of differentiation 8) • IL2RA (Interleukin 2 receptor, alpha) • CD69 (CD69 Molecule) • GZMB (Granzyme B)
|
EGFR H1975
|
Tagrisso (osimertinib) • Vectibix (panitumumab) • BC3448