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DRUG:

Imdelltra (tarlatamab-dlle)

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Company:

Amgen, BeiGene

Drug class:

CD3 agonist, DLL3 inhibitor

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No biomarker	Small Cell Lung Cancer	No biomarker	Small Cell Lung Cancer	tarlatamab-dlle Sensitive: B - Late Trials tarlatamab-dlle Sensitive : B	tarlatamab-dlle Sensitive: B - Late Trials tarlatamab-dlle Sensitive : B
DLL3 expression	Small Cell Lung Cancer	DLL3 expression	Small Cell Lung Cancer	tarlatamab-dlle Sensitive: C3 – Early Trials tarlatamab-dlle Sensitive : C3	tarlatamab-dlle Sensitive: C3 – Early Trials tarlatamab-dlle Sensitive : C3
DLL3 positive	Non Small Cell Lung Cancer	DLL3 positive	Non Small Cell Lung Cancer	tarlatamab-dlle Sensitive: C3 – Early Trials tarlatamab-dlle Sensitive : C3	tarlatamab-dlle Sensitive: C3 – Early Trials tarlatamab-dlle Sensitive : C3
DLL3 underexpression	Small Cell Lung Cancer	DLL3 underexpression	Small Cell Lung Cancer	tarlatamab-dlle Sensitive: D – Preclinical tarlatamab-dlle Sensitive : D	tarlatamab-dlle Sensitive: D – Preclinical tarlatamab-dlle Sensitive : D