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DRUG:

varlitinib (ASLAN001)

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Company:

ASLAN Pharma, Blade Entertaintment, Pfizer

Drug class:

EGFR inhibitor, HER2 inhibitor, HER4 inhibitor

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HER-2 overexpression	Gastric Cancer	HER-2 overexpression	Gastric Cancer	ASLAN001 Sensitive: C2 – Inclusion Criteria ASLAN001 Sensitive : C2	ASLAN001 Sensitive: C2 – Inclusion Criteria ASLAN001 Sensitive : C2
HER-2 positive	HER2 Positive Breast Cancer	HER-2 positive	HER2 Positive Breast Cancer	ASLAN001 Sensitive: C2 – Inclusion Criteria ASLAN001 Sensitive : C2	ASLAN001 Sensitive: C2 – Inclusion Criteria ASLAN001 Sensitive : C2
EGFR overexpression	Gastric Cancer	EGFR overexpression	Gastric Cancer	ASLAN001 Sensitive: C3 – Early Trials ASLAN001 Sensitive : C3	ASLAN001 Sensitive: C3 – Early Trials ASLAN001 Sensitive : C3
EGFR expression + HER-2 expression	Gastric Cancer	EGFR expression + HER-2 expression	Gastric Cancer	ASLAN001 Sensitive: C3 – Early Trials ASLAN001 Sensitive : C3	ASLAN001 Sensitive: C3 – Early Trials ASLAN001 Sensitive : C3
EGFR overexpression + HER-2 overexpression	Cholangiocarcinoma	EGFR overexpression + HER-2 overexpression	Cholangiocarcinoma	ASLAN001 Sensitive: D – Preclinical ASLAN001 Sensitive : D	ASLAN001 Sensitive: D – Preclinical ASLAN001 Sensitive : D
EGFR overexpression + HER-2 overexpression	Cholangiocarcinoma	EGFR overexpression + HER-2 overexpression	Cholangiocarcinoma	AN2025 + ASLAN001 Sensitive: D – Preclinical AN2025 + ASLAN001 Sensitive : D	AN2025 + ASLAN001 Sensitive: D – Preclinical AN2025 + ASLAN001 Sensitive : D