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DRUG:

Tarlox (tarloxotinib bromide)

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Company:

Molecular Templates, Pathos, Proacta, Signpath Pharma

Drug class:

EGFR inhibitor

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NRG1 fusion	Solid Tumor	NRG1 fusion	Solid Tumor	tarloxotinib bromide Sensitive: C2 – Inclusion Criteria tarloxotinib bromide Sensitive : C2	tarloxotinib bromide Sensitive: C2 – Inclusion Criteria tarloxotinib bromide Sensitive : C2
HER-2 mutation	Solid Tumor	HER-2 mutation	Solid Tumor	tarloxotinib bromide Sensitive: C2 – Inclusion Criteria tarloxotinib bromide Sensitive : C2	tarloxotinib bromide Sensitive: C2 – Inclusion Criteria tarloxotinib bromide Sensitive : C2
EGFR exon 20 mutation	Solid Tumor	EGFR exon 20 mutation	Solid Tumor	tarloxotinib bromide Sensitive: C2 – Inclusion Criteria tarloxotinib bromide Sensitive : C2	tarloxotinib bromide Sensitive: C2 – Inclusion Criteria tarloxotinib bromide Sensitive : C2
EGFR exon 20 insertion	Non Small Cell Lung Cancer	EGFR exon 20 insertion	Non Small Cell Lung Cancer	tarloxotinib bromide Sensitive: C2 – Inclusion Criteria tarloxotinib bromide Sensitive : C2	tarloxotinib bromide Sensitive: C2 – Inclusion Criteria tarloxotinib bromide Sensitive : C2
HER-2 mutation	Non Small Cell Lung Cancer	HER-2 mutation	Non Small Cell Lung Cancer	tarloxotinib bromide Sensitive: C2 – Inclusion Criteria tarloxotinib bromide Sensitive : C2	tarloxotinib bromide Sensitive: C2 – Inclusion Criteria tarloxotinib bromide Sensitive : C2
HER-2 A775_G776insYVMA	Lung Adenocarcinoma	HER-2 A775_G776insYVMA	Lung Adenocarcinoma	tarloxotinib bromide Sensitive: C4 – Case Studies tarloxotinib bromide Sensitive : C4	tarloxotinib bromide Sensitive: C4 – Case Studies tarloxotinib bromide Sensitive : C4
HER-2 amplification	Solid Tumor	HER-2 amplification	Solid Tumor	tarloxotinib bromide Sensitive: D – Preclinical tarloxotinib bromide Sensitive : D	tarloxotinib bromide Sensitive: D – Preclinical tarloxotinib bromide Sensitive : D