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DRUG:

obrixtamig (BI 764532)

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Company:

Boehringer Ingelheim, Oxford BioTherap

Drug class:

CD3 agonist, DLL3 inhibitor

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PF-07260437 (0)

catumaxomab (0)

UMG2-CD3 BTCE (0)

Undisclosed HER2Bi-armed ATC (0)

activated CIK and bispecific antibody (0)

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ABBV-383 IV (0)

huCD33-BsAb (0)

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No biomarker	Small Cell Lung Cancer	No biomarker	Small Cell Lung Cancer	BI 764532 Sensitive: B - Late Trials BI 764532 Sensitive : B	BI 764532 Sensitive: B - Late Trials BI 764532 Sensitive : B
No biomarker	Neuroendocrine Tumor	No biomarker	Neuroendocrine Tumor	BI 764532 Sensitive: B - Late Trials BI 764532 Sensitive : B	BI 764532 Sensitive: B - Late Trials BI 764532 Sensitive : B
DLL3 expression	Neuroendocrine Tumor	DLL3 expression	Neuroendocrine Tumor	BI 764532 Sensitive: B - Late Trials BI 764532 Sensitive : B	BI 764532 Sensitive: B - Late Trials BI 764532 Sensitive : B
DLL3 positive	Small Cell Lung Cancer	DLL3 positive	Small Cell Lung Cancer	BI 764532 Sensitive: C3 – Early Trials BI 764532 Sensitive : C3	BI 764532 Sensitive: C3 – Early Trials BI 764532 Sensitive : C3
DLL3 positive	Neuroendocrine Tumor	DLL3 positive	Neuroendocrine Tumor	BI 764532 Sensitive: C3 – Early Trials BI 764532 Sensitive : C3	BI 764532 Sensitive: C3 – Early Trials BI 764532 Sensitive : C3