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DRUG:
Nerlynx (neratinib)
i
Other names:
HKI-272, PB-272, PB272, PF-0528767, WAY-179272, HKI272, HKI 272, PB 272, PF0528767, PF 0528767, WAY179272, WAY 179272
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Associations
(102)
News
Trials
Company:
Convalife, Fosun Pharma, Knight Therap, Pierre Fabre, Puma, Specialised Therap
Drug class:
EGFR inhibitor, HER2 inhibitor, HER4 inhibitor
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trastuzumab biosimilar (0)
trastuzumab biosimilar (0)
›
Associations
(102)
News
Trials
VERI cancer hierarchy
Reset Filters
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
HER-2 overexpression
Hormone Receptor Positive Breast Cancer
HER-2 overexpression
Hormone Receptor Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
HER-2 amplification
Hormone Receptor Positive Breast Cancer
HER-2 amplification
Hormone Receptor Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
HER-2 amplification
HER2 Positive Breast Cancer
HER-2 amplification
HER2 Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
HER-2 overexpression
HER2 Positive Breast Cancer
HER-2 overexpression
HER2 Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
ER positive
HER2 Positive Breast Cancer
ER positive
HER2 Positive Breast Cancer
neratinib
Sensitive: A2 - Guideline
neratinib
Sensitive
:
A2
neratinib
Sensitive: A2 - Guideline
neratinib
Sensitive
:
A2
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
trastuzumab + neratinib
Sensitive: B - Late Trials
trastuzumab + neratinib
Sensitive
:
B
trastuzumab + neratinib
Sensitive: B - Late Trials
trastuzumab + neratinib
Sensitive
:
B
HER-2 overexpression
Breast Cancer
HER-2 overexpression
Breast Cancer
neratinib
Sensitive: B - Late Trials
neratinib
Sensitive
:
B
neratinib
Sensitive: B - Late Trials
neratinib
Sensitive
:
B
PIK3CA mutation
HER2 Positive Breast Cancer
PIK3CA mutation
HER2 Positive Breast Cancer
neratinib
Resistant: B - Late Trials
neratinib
Resistant
:
B
neratinib
Resistant: B - Late Trials
neratinib
Resistant
:
B
HER-2 amplification
Breast Cancer
HER-2 amplification
Breast Cancer
neratinib
Sensitive: C1 - Off-label
neratinib
Sensitive
:
C1
neratinib
Sensitive: C1 - Off-label
neratinib
Sensitive
:
C1
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
neratinib
Sensitive: C1 - Off-label
neratinib
Sensitive
:
C1
neratinib
Sensitive: C1 - Off-label
neratinib
Sensitive
:
C1
HER-2 positive
Solid Tumor
HER-2 positive
Solid Tumor
neratinib
Resistant: C1 - Off-label
neratinib
Resistant
:
C1
neratinib
Resistant: C1 - Off-label
neratinib
Resistant
:
C1
HER-2 positive
Biliary Tract Cancer
HER-2 positive
Biliary Tract Cancer
neratinib
Sensitive: C1 - Off-label
neratinib
Sensitive
:
C1
neratinib
Sensitive: C1 - Off-label
neratinib
Sensitive
:
C1
HR positive
Hormone Receptor Positive Breast Cancer
HR positive
Hormone Receptor Positive Breast Cancer
trastuzumab + neratinib
Sensitive: C2 – Inclusion Criteria
trastuzumab + neratinib
Sensitive
:
C2
trastuzumab + neratinib
Sensitive: C2 – Inclusion Criteria
trastuzumab + neratinib
Sensitive
:
C2
HER-2 mutation
Hormone Receptor Positive Breast Cancer
HER-2 mutation
Hormone Receptor Positive Breast Cancer
trastuzumab + neratinib
Sensitive: C2 – Inclusion Criteria
trastuzumab + neratinib
Sensitive
:
C2
trastuzumab + neratinib
Sensitive: C2 – Inclusion Criteria
trastuzumab + neratinib
Sensitive
:
C2
EGFR exon 18 mutation
Non Small Cell Lung Cancer
EGFR exon 18 mutation
Non Small Cell Lung Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
neratinib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
neratinib + ado-trastuzumab emtansine
Sensitive
:
C2
neratinib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
neratinib + ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 mutation
Cervical Cancer
HER-2 mutation
Cervical Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 amplification
HER2 Positive Breast Cancer
HER-2 amplification
HER2 Positive Breast Cancer
neratinib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
neratinib + ado-trastuzumab emtansine
Sensitive
:
C2
neratinib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
neratinib + ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 D769H
HER2 Negative Breast Cancer
HER-2 D769H
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 D769Y
HER2 Negative Breast Cancer
HER-2 D769Y
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 L755S
HER2 Negative Breast Cancer
HER-2 L755S
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 R896C
HER2 Negative Breast Cancer
HER-2 R896C
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 V777L
HER2 Negative Breast Cancer
HER-2 V777L
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 V842I
HER2 Negative Breast Cancer
HER-2 V842I
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 mutation
Breast Cancer
HER-2 mutation
Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
EGFR G719X
Non Small Cell Lung Cancer
EGFR G719X
Non Small Cell Lung Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 mutation
Non Small Cell Lung Cancer
HER-2 mutation
Non Small Cell Lung Cancer
trastuzumab + neratinib
Sensitive: C3 – Early Trials
trastuzumab + neratinib
Sensitive
:
C3
trastuzumab + neratinib
Sensitive: C3 – Early Trials
trastuzumab + neratinib
Sensitive
:
C3
HER-2 mutation
Non Small Cell Lung Cancer
HER-2 mutation
Non Small Cell Lung Cancer
neratinib + temsirolimus
Sensitive: C3 – Early Trials
neratinib + temsirolimus
Sensitive
:
C3
neratinib + temsirolimus
Sensitive: C3 – Early Trials
neratinib + temsirolimus
Sensitive
:
C3
HER-2 mutation
Biliary Tract Cancer
HER-2 mutation
Biliary Tract Cancer
neratinib
Sensitive: C3 – Early Trials
neratinib
Sensitive
:
C3
neratinib
Sensitive: C3 – Early Trials
neratinib
Sensitive
:
C3
HER-2 mutation
HER2 Positive Breast Cancer
HER-2 mutation
HER2 Positive Breast Cancer
neratinib
Sensitive: C3 – Early Trials
neratinib
Sensitive
:
C3
neratinib
Sensitive: C3 – Early Trials
neratinib
Sensitive
:
C3
^
^
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