Login
Evidence Feed
About
Diagnostics
New
Top genes
FAQ
Contact us
^
Login
Contact us
to learn more about
our Premium Content: News alerts, weekly reports and conference planners
DRUG:
Nerlynx (neratinib)
i
Other names:
HKI 272, PB 272, PF0528767, PF 0528767, WAY179272, WAY 179272, HKI-272, PB-272, PB272, PF-0528767, WAY-179272, HKI272
Contact us
to learn more about our Premium Content:
News alerts, weekly reports and conference planners
Associations
(102)
News
Trials
Company:
Convalife, Fosun Pharma, Knight Therap, Pierre Fabre, Puma, Specialised Therap
Drug class:
EGFR inhibitor, HER2 inhibitor, HER4 inhibitor
Related drugs:
‹
cetuximab (347)
osimertinib (301)
erlotinib (235)
afatinib (227)
gefitinib (194)
panitumumab (123)
lapatinib (107)
pyrotinib (79)
brigatinib (50)
icotinib (45)
aumolertinib (39)
amivantamab-vmjw (25)
firmonertinib (14)
mobocertinib (12)
lazertinib (12)
BGB-283 (12)
tarloxotinib bromide (7)
WZ4002 (7)
CH7233163 (6)
H002 (6)
nimotuzumab (6)
BLU-945 (6)
ASLAN001 (6)
BBT-176 (5)
CL-387785 (5)
GB263T (5)
rociletinib (5)
BDTX-189 (5)
AEE788 (4)
BDTX-1535 (4)
BI-4020 (4)
tomuzotuximab (4)
JIN-A02 (4)
TAS2940 (4)
VRN11 (4)
MET306 (4)
EGF816 (4)
AFM24 (3)
BLU-701 (3)
GC-1118A (3)
necitumumab (3)
befotertinib (3)
zorifertinib (3)
BCA101 (3)
S95026 (3)
ASP8273 (3)
MCLA-129 (3)
DZD9008 (3)
SZMD4 (3)
ACE2016 (2)
BI-732 (2)
BLU-451 (2)
Bay846 (2)
ERAS-801 (2)
OBX02-011 (2)
olmutinib (2)
QL1203 (2)
CLN-081 (2)
14aj (1)
ABN202 (1)
ABP 494 (cetuximab biosimilar) (1)
APL-103 (1)
BAY 2927088 (1)
BPI-15086 (1)
BPI-361175 (1)
Compound 6a (1)
abivertinib (1)
KKI04 (1)
PH001 (1)
rilertinib (1)
TAS3351 (1)
TRX-221 (1)
WSD0922 (1)
JMT101 (1)
S-222611 (1)
HMPL-813 (1)
SI-B001 (1)
ASK120067 (1)
HLX07 (1)
Hemay022 (1)
KD019 (1)
ABT-101 (0)
AC480 (0)
AG1478 (0)
BBT-207 (0)
BC3448 (0)
BMS690514 (0)
CM93 (0)
CUDC-101 (0)
EGF-PTI (0)
DF9001 (0)
DK210 (0)
STI-001 (cetuximab biosimilar) (0)
FHND9041 (0)
HLX35 (0)
HS-10375 (0)
antroquinonol (0)
zalutumumab (0)
IAE0972 (0)
IBI-334 (0)
JANX008 (0)
JNJ-26483327 (0)
JS111 (0)
MM-151 (0)
MP412 (0)
MTX-211 (0)
PF-08046052 (0)
PLB1004 (0)
PM1080 (0)
QLH11811 (0)
rindopepimut (0)
SR13668 (0)
SYN004 (0)
Sym013 (0)
TAK-186 (0)
TAK-285 (0)
TAS-121 (0)
TAVO412 (0)
THE-349 (0)
TQ-B3456 (0)
TQB3804 (0)
U3-1565 (0)
Undisclosed EGFR inhibitor (0)
XZP-5809 (0)
simotinib (0)
ZN-e4 (0)
AST1306 (0)
SY101 (0)
Ami-LC (0)
TY-9591 (0)
EMB-01 (0)
cetuximab biosimilar (0)
cipatinib (0)
ABT-806 (0)
MEHD7945A (0)
RO5083945 (0)
TL007 (0)
EMD 72000 (0)
PF-06747775 (0)
JNJ-64041757 (0)
KBP-5209 (0)
SKLB-1028 (0)
AZD8931 (0)
trastuzumab (407)
tucatinib (39)
trastuzumab-pkrb (24)
margetuximab-cmkb (18)
poziotinib (17)
zenocutuzumab-zbco (16)
KN026 (14)
trastuzumab-dttb (11)
zanidatamab-hrii (10)
trastuzumab-strf (9)
trastuzumab-anns (9)
trastuzumab-dkst (9)
trastuzumab-qyyp (9)
LZM-005 (8)
PRS-343 (8)
D3L-001 (7)
inetetamab (6)
MT-5111 (4)
Undisclosed allogeneic Vγ9Vδ2 HER2-TAC T (4)
pertuzumab/trastuzumab/hyaluronidase-zzxf (3)
trastuzumab-IFN-β mutein (3)
AST-301 (2)
CT-0508 (2)
DF1001 (2)
ER121 (2)
Her-VAXX (2)
trastuzumab/hyaluronidase-oysk (2)
JBJ-08–178–01 (2)
VIR-5818 (2)
BDC-1001 (2)
ABL105 (1)
ACE1702 (1)
Hercease (trastuzumab biosimilar) (1)
BAY2701439 (1)
DZD1516 (1)
GCC2003 (1)
HERtiCAD (trastuzumab biosimilar) (1)
Hervelous (trastuzumab biosimilar) (1)
EG12014 (trastuzumab biosimilar) (1)
IAH0968 (1)
IMM2902 (1)
MP0274 (1)
RG6596 (1)
SAR443216 (1)
(1)
TX05 (trastuzumab biosimilar) (1)
VRN101099 (1)
ADG138 (0)
ALT02 (trastuzumab biosimilar) (0)
trastuzumab biosimilar (AP062) (0)
B-Vaxx (0)
BAT1006 (0)
BAY2701438 (0)
CAM-H2 (0)
CAT-179 (0)
DA 3111 (trastuzumab biosimilar) (0)
(0)
ELVN-002 (0)
ES2B-C001 (0)
ETBX-021 (0)
(0)
GB235 (0)
HER-2/neu peptide vaccine (0)
HER2 t-haNK (0)
HF158K1 (0)
HLX11 (pertuzumab biosimilar) (0)
Hervycta (trastuzumab biosimilar) (0)
ISB 1302 (0)
OST-HER2 (0)
MBS301 (0)
MM 111 (0)
MVA-BN-HER2 (0)
NVL-330 (0)
NeuCeptin (trastuzumab biosimilar) (0)
nelipepimut-S (0)
lapuleucel-T (0)
OS47701 (0)
QP34563457 (0)
ertumaxomab (0)
trastuzumab biosimilar (SIBP-01) (0)
SPH5030 (0)
SSGJ-705 (0)
(0)
TAC100-HER2 (0)
TAS0728 (0)
TPIV100 (0)
TQB2930 (0)
glycooptimized trastuzumab-GEX (0)
TrastuRel (trastuzumab biosimilar) (0)
Undisclosed HER2Bi-armed ATC (0)
VM 206 (0)
YH42946 (0)
dHER2+AS15 (0)
IBI315 (0)
RG6194 (0)
trastuzumab biosimilar (0)
trastuzumab biosimilar (0)
cetuximab (347)
osimertinib (301)
erlotinib (235)
afatinib (227)
gefitinib (194)
panitumumab (123)
lapatinib (107)
pyrotinib (79)
brigatinib (50)
icotinib (45)
aumolertinib (39)
amivantamab-vmjw (25)
firmonertinib (14)
mobocertinib (12)
lazertinib (12)
BGB-283 (12)
tarloxotinib bromide (7)
WZ4002 (7)
CH7233163 (6)
H002 (6)
nimotuzumab (6)
BLU-945 (6)
ASLAN001 (6)
BBT-176 (5)
CL-387785 (5)
GB263T (5)
rociletinib (5)
BDTX-189 (5)
AEE788 (4)
BDTX-1535 (4)
BI-4020 (4)
tomuzotuximab (4)
JIN-A02 (4)
TAS2940 (4)
VRN11 (4)
MET306 (4)
EGF816 (4)
AFM24 (3)
BLU-701 (3)
GC-1118A (3)
necitumumab (3)
befotertinib (3)
zorifertinib (3)
BCA101 (3)
S95026 (3)
ASP8273 (3)
MCLA-129 (3)
DZD9008 (3)
SZMD4 (3)
ACE2016 (2)
BI-732 (2)
BLU-451 (2)
Bay846 (2)
ERAS-801 (2)
OBX02-011 (2)
olmutinib (2)
QL1203 (2)
CLN-081 (2)
14aj (1)
ABN202 (1)
ABP 494 (cetuximab biosimilar) (1)
APL-103 (1)
BAY 2927088 (1)
BPI-15086 (1)
BPI-361175 (1)
Compound 6a (1)
abivertinib (1)
KKI04 (1)
PH001 (1)
rilertinib (1)
TAS3351 (1)
TRX-221 (1)
WSD0922 (1)
JMT101 (1)
S-222611 (1)
HMPL-813 (1)
SI-B001 (1)
ASK120067 (1)
HLX07 (1)
Hemay022 (1)
KD019 (1)
ABT-101 (0)
AC480 (0)
AG1478 (0)
BBT-207 (0)
BC3448 (0)
BMS690514 (0)
CM93 (0)
CUDC-101 (0)
EGF-PTI (0)
DF9001 (0)
DK210 (0)
STI-001 (cetuximab biosimilar) (0)
FHND9041 (0)
HLX35 (0)
HS-10375 (0)
antroquinonol (0)
zalutumumab (0)
IAE0972 (0)
IBI-334 (0)
JANX008 (0)
JNJ-26483327 (0)
JS111 (0)
MM-151 (0)
MP412 (0)
MTX-211 (0)
PF-08046052 (0)
PLB1004 (0)
PM1080 (0)
QLH11811 (0)
rindopepimut (0)
SR13668 (0)
SYN004 (0)
Sym013 (0)
TAK-186 (0)
TAK-285 (0)
TAS-121 (0)
TAVO412 (0)
THE-349 (0)
TQ-B3456 (0)
TQB3804 (0)
U3-1565 (0)
Undisclosed EGFR inhibitor (0)
XZP-5809 (0)
simotinib (0)
ZN-e4 (0)
AST1306 (0)
SY101 (0)
Ami-LC (0)
TY-9591 (0)
EMB-01 (0)
cetuximab biosimilar (0)
cipatinib (0)
ABT-806 (0)
MEHD7945A (0)
RO5083945 (0)
TL007 (0)
EMD 72000 (0)
PF-06747775 (0)
JNJ-64041757 (0)
KBP-5209 (0)
SKLB-1028 (0)
AZD8931 (0)
trastuzumab (407)
tucatinib (39)
trastuzumab-pkrb (24)
margetuximab-cmkb (18)
poziotinib (17)
zenocutuzumab-zbco (16)
KN026 (14)
trastuzumab-dttb (11)
zanidatamab-hrii (10)
trastuzumab-strf (9)
trastuzumab-anns (9)
trastuzumab-dkst (9)
trastuzumab-qyyp (9)
LZM-005 (8)
PRS-343 (8)
D3L-001 (7)
inetetamab (6)
MT-5111 (4)
Undisclosed allogeneic Vγ9Vδ2 HER2-TAC T (4)
pertuzumab/trastuzumab/hyaluronidase-zzxf (3)
trastuzumab-IFN-β mutein (3)
AST-301 (2)
CT-0508 (2)
DF1001 (2)
ER121 (2)
Her-VAXX (2)
trastuzumab/hyaluronidase-oysk (2)
JBJ-08–178–01 (2)
VIR-5818 (2)
BDC-1001 (2)
ABL105 (1)
ACE1702 (1)
Hercease (trastuzumab biosimilar) (1)
BAY2701439 (1)
DZD1516 (1)
GCC2003 (1)
HERtiCAD (trastuzumab biosimilar) (1)
Hervelous (trastuzumab biosimilar) (1)
EG12014 (trastuzumab biosimilar) (1)
IAH0968 (1)
IMM2902 (1)
MP0274 (1)
RG6596 (1)
SAR443216 (1)
(1)
TX05 (trastuzumab biosimilar) (1)
VRN101099 (1)
ADG138 (0)
ALT02 (trastuzumab biosimilar) (0)
trastuzumab biosimilar (AP062) (0)
B-Vaxx (0)
BAT1006 (0)
BAY2701438 (0)
CAM-H2 (0)
CAT-179 (0)
DA 3111 (trastuzumab biosimilar) (0)
(0)
ELVN-002 (0)
ES2B-C001 (0)
ETBX-021 (0)
(0)
GB235 (0)
HER-2/neu peptide vaccine (0)
HER2 t-haNK (0)
HF158K1 (0)
HLX11 (pertuzumab biosimilar) (0)
Hervycta (trastuzumab biosimilar) (0)
ISB 1302 (0)
OST-HER2 (0)
MBS301 (0)
MM 111 (0)
MVA-BN-HER2 (0)
NVL-330 (0)
NeuCeptin (trastuzumab biosimilar) (0)
nelipepimut-S (0)
lapuleucel-T (0)
OS47701 (0)
QP34563457 (0)
ertumaxomab (0)
trastuzumab biosimilar (SIBP-01) (0)
SPH5030 (0)
SSGJ-705 (0)
(0)
TAC100-HER2 (0)
TAS0728 (0)
TPIV100 (0)
TQB2930 (0)
glycooptimized trastuzumab-GEX (0)
TrastuRel (trastuzumab biosimilar) (0)
Undisclosed HER2Bi-armed ATC (0)
VM 206 (0)
YH42946 (0)
dHER2+AS15 (0)
IBI315 (0)
RG6194 (0)
trastuzumab biosimilar (0)
trastuzumab biosimilar (0)
›
Associations
(102)
News
Trials
VERI cancer hierarchy
Reset Filters
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
HER-2 overexpression
Hormone Receptor Positive Breast Cancer
HER-2 overexpression
Hormone Receptor Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
HER-2 amplification
Hormone Receptor Positive Breast Cancer
HER-2 amplification
Hormone Receptor Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
HER-2 amplification
HER2 Positive Breast Cancer
HER-2 amplification
HER2 Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
HER-2 overexpression
HER2 Positive Breast Cancer
HER-2 overexpression
HER2 Positive Breast Cancer
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
neratinib
Sensitive: A1 - Approval
neratinib
Sensitive
:
A1
ER positive
HER2 Positive Breast Cancer
ER positive
HER2 Positive Breast Cancer
neratinib
Sensitive: A2 - Guideline
neratinib
Sensitive
:
A2
neratinib
Sensitive: A2 - Guideline
neratinib
Sensitive
:
A2
HR positive
HER2 Positive Breast Cancer
HR positive
HER2 Positive Breast Cancer
trastuzumab + neratinib
Sensitive: B - Late Trials
trastuzumab + neratinib
Sensitive
:
B
trastuzumab + neratinib
Sensitive: B - Late Trials
trastuzumab + neratinib
Sensitive
:
B
HER-2 overexpression
Breast Cancer
HER-2 overexpression
Breast Cancer
neratinib
Sensitive: B - Late Trials
neratinib
Sensitive
:
B
neratinib
Sensitive: B - Late Trials
neratinib
Sensitive
:
B
PIK3CA mutation
HER2 Positive Breast Cancer
PIK3CA mutation
HER2 Positive Breast Cancer
neratinib
Resistant: B - Late Trials
neratinib
Resistant
:
B
neratinib
Resistant: B - Late Trials
neratinib
Resistant
:
B
HER-2 amplification
Breast Cancer
HER-2 amplification
Breast Cancer
neratinib
Sensitive: C1 - Off-label
neratinib
Sensitive
:
C1
neratinib
Sensitive: C1 - Off-label
neratinib
Sensitive
:
C1
HR positive
HER2 Negative Breast Cancer
HR positive
HER2 Negative Breast Cancer
neratinib
Sensitive: C1 - Off-label
neratinib
Sensitive
:
C1
neratinib
Sensitive: C1 - Off-label
neratinib
Sensitive
:
C1
HER-2 positive
Solid Tumor
HER-2 positive
Solid Tumor
neratinib
Resistant: C1 - Off-label
neratinib
Resistant
:
C1
neratinib
Resistant: C1 - Off-label
neratinib
Resistant
:
C1
HER-2 positive
Biliary Tract Cancer
HER-2 positive
Biliary Tract Cancer
neratinib
Sensitive: C1 - Off-label
neratinib
Sensitive
:
C1
neratinib
Sensitive: C1 - Off-label
neratinib
Sensitive
:
C1
HR positive
Hormone Receptor Positive Breast Cancer
HR positive
Hormone Receptor Positive Breast Cancer
trastuzumab + neratinib
Sensitive: C2 – Inclusion Criteria
trastuzumab + neratinib
Sensitive
:
C2
trastuzumab + neratinib
Sensitive: C2 – Inclusion Criteria
trastuzumab + neratinib
Sensitive
:
C2
HER-2 mutation
Hormone Receptor Positive Breast Cancer
HER-2 mutation
Hormone Receptor Positive Breast Cancer
trastuzumab + neratinib
Sensitive: C2 – Inclusion Criteria
trastuzumab + neratinib
Sensitive
:
C2
trastuzumab + neratinib
Sensitive: C2 – Inclusion Criteria
trastuzumab + neratinib
Sensitive
:
C2
EGFR exon 18 mutation
Non Small Cell Lung Cancer
EGFR exon 18 mutation
Non Small Cell Lung Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 positive
HER2 Positive Breast Cancer
HER-2 positive
HER2 Positive Breast Cancer
neratinib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
neratinib + ado-trastuzumab emtansine
Sensitive
:
C2
neratinib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
neratinib + ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 mutation
Cervical Cancer
HER-2 mutation
Cervical Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 amplification
HER2 Positive Breast Cancer
HER-2 amplification
HER2 Positive Breast Cancer
neratinib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
neratinib + ado-trastuzumab emtansine
Sensitive
:
C2
neratinib + ado-trastuzumab emtansine
Sensitive: C2 – Inclusion Criteria
neratinib + ado-trastuzumab emtansine
Sensitive
:
C2
HER-2 D769H
HER2 Negative Breast Cancer
HER-2 D769H
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 D769Y
HER2 Negative Breast Cancer
HER-2 D769Y
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 L755S
HER2 Negative Breast Cancer
HER-2 L755S
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 R896C
HER2 Negative Breast Cancer
HER-2 R896C
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 V777L
HER2 Negative Breast Cancer
HER-2 V777L
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 V842I
HER2 Negative Breast Cancer
HER-2 V842I
HER2 Negative Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 mutation
Breast Cancer
HER-2 mutation
Breast Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
EGFR G719X
Non Small Cell Lung Cancer
EGFR G719X
Non Small Cell Lung Cancer
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
neratinib
Sensitive: C2 – Inclusion Criteria
neratinib
Sensitive
:
C2
HER-2 mutation
Non Small Cell Lung Cancer
HER-2 mutation
Non Small Cell Lung Cancer
trastuzumab + neratinib
Sensitive: C3 – Early Trials
trastuzumab + neratinib
Sensitive
:
C3
trastuzumab + neratinib
Sensitive: C3 – Early Trials
trastuzumab + neratinib
Sensitive
:
C3
HER-2 mutation
Non Small Cell Lung Cancer
HER-2 mutation
Non Small Cell Lung Cancer
neratinib + temsirolimus
Sensitive: C3 – Early Trials
neratinib + temsirolimus
Sensitive
:
C3
neratinib + temsirolimus
Sensitive: C3 – Early Trials
neratinib + temsirolimus
Sensitive
:
C3
HER-2 mutation
Biliary Tract Cancer
HER-2 mutation
Biliary Tract Cancer
neratinib
Sensitive: C3 – Early Trials
neratinib
Sensitive
:
C3
neratinib
Sensitive: C3 – Early Trials
neratinib
Sensitive
:
C3
HER-2 mutation
HER2 Positive Breast Cancer
HER-2 mutation
HER2 Positive Breast Cancer
neratinib
Sensitive: C3 – Early Trials
neratinib
Sensitive
:
C3
neratinib
Sensitive: C3 – Early Trials
neratinib
Sensitive
:
C3
^
^
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login
Full access to predictive biomarker details and heatmap analytics are available with a VERI Account.
Sign up for FREE
Already have an account?
Login