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DRUG:

Elrexfio (elranatamab-bcmm)

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Company:

Pfizer

Drug class:

CD3 agonist, BCMA inhibitor

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No biomarker	Multiple Myeloma	No biomarker	Multiple Myeloma	elranatamab-bcmm Sensitive: A1 - Approval elranatamab-bcmm Sensitive : A1	elranatamab-bcmm Sensitive: A1 - Approval elranatamab-bcmm Sensitive : A1
IL6-L	Multiple Myeloma	IL6-L	Multiple Myeloma	elranatamab-bcmm Sensitive: C3 – Early Trials elranatamab-bcmm Sensitive : C3	elranatamab-bcmm Sensitive: C3 – Early Trials elranatamab-bcmm Sensitive : C3
TNFRSF17 amplification	Multiple Myeloma	TNFRSF17 amplification	Multiple Myeloma	elranatamab-bcmm Resistant: C3 – Early Trials elranatamab-bcmm Resistant : C3	elranatamab-bcmm Resistant: C3 – Early Trials elranatamab-bcmm Resistant : C3
CCL3-L	Multiple Myeloma	CCL3-L	Multiple Myeloma	elranatamab-bcmm Sensitive: C3 – Early Trials elranatamab-bcmm Sensitive : C3	elranatamab-bcmm Sensitive: C3 – Early Trials elranatamab-bcmm Sensitive : C3
IL17C-L	Multiple Myeloma	IL17C-L	Multiple Myeloma	elranatamab-bcmm Sensitive: C3 – Early Trials elranatamab-bcmm Sensitive : C3	elranatamab-bcmm Sensitive: C3 – Early Trials elranatamab-bcmm Sensitive : C3
Chr del(17p)	Multiple Myeloma	Chr del(17p)	Multiple Myeloma	elranatamab-bcmm Sensitive: C3 – Early Trials elranatamab-bcmm Sensitive : C3	elranatamab-bcmm Sensitive: C3 – Early Trials elranatamab-bcmm Sensitive : C3
Chr t(14;16)	Multiple Myeloma	Chr t(14;16)	Multiple Myeloma	elranatamab-bcmm Sensitive: C3 – Early Trials elranatamab-bcmm Sensitive : C3	elranatamab-bcmm Sensitive: C3 – Early Trials elranatamab-bcmm Sensitive : C3
Chr t(4;14)	Multiple Myeloma	Chr t(4;14)	Multiple Myeloma	elranatamab-bcmm Sensitive: C3 – Early Trials elranatamab-bcmm Sensitive : C3	elranatamab-bcmm Sensitive: C3 – Early Trials elranatamab-bcmm Sensitive : C3