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DRUG:
Rybrevant (amivantamab-vmjw)
i
Other names:
JNJ 61186372, JNJ 6372, JNJ-61186372, EM1-mAb, JNJ 372, JNJ-372, JNJ-6372 , JNJ372, JNJ61186372, JNJ6372
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Associations
(25)
News
Trials
Company:
Genmab, J&J
Drug class:
EGFR inhibitor, c-MET inhibitor
Related drugs:
‹
cetuximab (347)
osimertinib (301)
erlotinib (235)
afatinib (227)
gefitinib (194)
panitumumab (123)
lapatinib (107)
neratinib (102)
pyrotinib (79)
brigatinib (50)
icotinib (45)
aumolertinib (39)
firmonertinib (14)
mobocertinib (12)
lazertinib (12)
BGB-283 (12)
tarloxotinib bromide (7)
WZ4002 (7)
CH7233163 (6)
H002 (6)
nimotuzumab (6)
BLU-945 (6)
ASLAN001 (6)
BBT-176 (5)
CL-387785 (5)
GB263T (5)
rociletinib (5)
BDTX-189 (5)
AEE788 (4)
BDTX-1535 (4)
BI-4020 (4)
tomuzotuximab (4)
JIN-A02 (4)
TAS2940 (4)
VRN11 (4)
MET306 (4)
EGF816 (4)
AFM24 (3)
BLU-701 (3)
GC-1118A (3)
necitumumab (3)
befotertinib (3)
zorifertinib (3)
BCA101 (3)
S95026 (3)
ASP8273 (3)
MCLA-129 (3)
DZD9008 (3)
SZMD4 (3)
ACE2016 (2)
BI-732 (2)
BLU-451 (2)
Bay846 (2)
ERAS-801 (2)
OBX02-011 (2)
olmutinib (2)
QL1203 (2)
CLN-081 (2)
14aj (1)
ABN202 (1)
ABP 494 (cetuximab biosimilar) (1)
APL-103 (1)
BAY 2927088 (1)
BPI-15086 (1)
BPI-361175 (1)
Compound 6a (1)
abivertinib (1)
KKI04 (1)
PH001 (1)
rilertinib (1)
TAS3351 (1)
TRX-221 (1)
WSD0922 (1)
JMT101 (1)
S-222611 (1)
HMPL-813 (1)
SI-B001 (1)
ASK120067 (1)
HLX07 (1)
Hemay022 (1)
KD019 (1)
ABT-101 (0)
AC480 (0)
AG1478 (0)
BBT-207 (0)
BC3448 (0)
BMS690514 (0)
CM93 (0)
CUDC-101 (0)
EGF-PTI (0)
DF9001 (0)
DK210 (0)
STI-001 (cetuximab biosimilar) (0)
FHND9041 (0)
HLX35 (0)
HS-10375 (0)
antroquinonol (0)
zalutumumab (0)
IAE0972 (0)
IBI-334 (0)
JANX008 (0)
JNJ-26483327 (0)
JS111 (0)
MM-151 (0)
MP412 (0)
MTX-211 (0)
PF-08046052 (0)
PLB1004 (0)
PM1080 (0)
QLH11811 (0)
rindopepimut (0)
SR13668 (0)
SYN004 (0)
Sym013 (0)
TAK-186 (0)
TAK-285 (0)
TAS-121 (0)
TAVO412 (0)
THE-349 (0)
TQ-B3456 (0)
TQB3804 (0)
U3-1565 (0)
Undisclosed EGFR inhibitor (0)
XZP-5809 (0)
simotinib (0)
ZN-e4 (0)
AST1306 (0)
SY101 (0)
Ami-LC (0)
TY-9591 (0)
EMB-01 (0)
cetuximab biosimilar (0)
cipatinib (0)
ABT-806 (0)
MEHD7945A (0)
RO5083945 (0)
TL007 (0)
EMD 72000 (0)
PF-06747775 (0)
JNJ-64041757 (0)
KBP-5209 (0)
SKLB-1028 (0)
AZD8931 (0)
savolitinib (29)
tepotinib (24)
capmatinib (23)
TPX-0022 (8)
unecritinib (6)
CKD-702 (6)
LY2801653 (6)
gumarontinib (5)
WXSH0011 (5)
ARQ 197 (5)
REGN5093 (4)
MGCD265 (4)
AMG 102 (4)
envonalkib (3)
ABN401 (3)
BPI-9016M (2)
HQP8361 (2)
HS-10241 (2)
S95027 (2)
APL-101 (2)
AV-299 (2)
GSK1363089 (2)
DO-1 (1)
GST-HG16 (1)
JNJ-38877605 (1)
KRC-108 (1)
SGX523 (1)
SU11274 (1)
LY2875358 (1)
E7050 (1)
RG3638 (1)
AL2846 (0)
AMG 208 (0)
AMG 337 (0)
ARGX-111 (0)
ASKC202 (0)
ASLAN002 (0)
DO-2 (0)
EMD 1204831 (0)
HLX55 (0)
MRX34 (0)
PF-04217903 (0)
PHA665752 (0)
RXDX-106 (0)
S-49076 (0)
SAIT301 (0)
SAR 125844 (0)
SPH 3348 (0)
DCC-2701 (0)
BMS-794833 (0)
h224G11 (0)
XL092 (0)
cetuximab (347)
osimertinib (301)
erlotinib (235)
afatinib (227)
gefitinib (194)
panitumumab (123)
lapatinib (107)
neratinib (102)
pyrotinib (79)
brigatinib (50)
icotinib (45)
aumolertinib (39)
firmonertinib (14)
mobocertinib (12)
lazertinib (12)
BGB-283 (12)
tarloxotinib bromide (7)
WZ4002 (7)
CH7233163 (6)
H002 (6)
nimotuzumab (6)
BLU-945 (6)
ASLAN001 (6)
BBT-176 (5)
CL-387785 (5)
GB263T (5)
rociletinib (5)
BDTX-189 (5)
AEE788 (4)
BDTX-1535 (4)
BI-4020 (4)
tomuzotuximab (4)
JIN-A02 (4)
TAS2940 (4)
VRN11 (4)
MET306 (4)
EGF816 (4)
AFM24 (3)
BLU-701 (3)
GC-1118A (3)
necitumumab (3)
befotertinib (3)
zorifertinib (3)
BCA101 (3)
S95026 (3)
ASP8273 (3)
MCLA-129 (3)
DZD9008 (3)
SZMD4 (3)
ACE2016 (2)
BI-732 (2)
BLU-451 (2)
Bay846 (2)
ERAS-801 (2)
OBX02-011 (2)
olmutinib (2)
QL1203 (2)
CLN-081 (2)
14aj (1)
ABN202 (1)
ABP 494 (cetuximab biosimilar) (1)
APL-103 (1)
BAY 2927088 (1)
BPI-15086 (1)
BPI-361175 (1)
Compound 6a (1)
abivertinib (1)
KKI04 (1)
PH001 (1)
rilertinib (1)
TAS3351 (1)
TRX-221 (1)
WSD0922 (1)
JMT101 (1)
S-222611 (1)
HMPL-813 (1)
SI-B001 (1)
ASK120067 (1)
HLX07 (1)
Hemay022 (1)
KD019 (1)
ABT-101 (0)
AC480 (0)
AG1478 (0)
BBT-207 (0)
BC3448 (0)
BMS690514 (0)
CM93 (0)
CUDC-101 (0)
EGF-PTI (0)
DF9001 (0)
DK210 (0)
STI-001 (cetuximab biosimilar) (0)
FHND9041 (0)
HLX35 (0)
HS-10375 (0)
antroquinonol (0)
zalutumumab (0)
IAE0972 (0)
IBI-334 (0)
JANX008 (0)
JNJ-26483327 (0)
JS111 (0)
MM-151 (0)
MP412 (0)
MTX-211 (0)
PF-08046052 (0)
PLB1004 (0)
PM1080 (0)
QLH11811 (0)
rindopepimut (0)
SR13668 (0)
SYN004 (0)
Sym013 (0)
TAK-186 (0)
TAK-285 (0)
TAS-121 (0)
TAVO412 (0)
THE-349 (0)
TQ-B3456 (0)
TQB3804 (0)
U3-1565 (0)
Undisclosed EGFR inhibitor (0)
XZP-5809 (0)
simotinib (0)
ZN-e4 (0)
AST1306 (0)
SY101 (0)
Ami-LC (0)
TY-9591 (0)
EMB-01 (0)
cetuximab biosimilar (0)
cipatinib (0)
ABT-806 (0)
MEHD7945A (0)
RO5083945 (0)
TL007 (0)
EMD 72000 (0)
PF-06747775 (0)
JNJ-64041757 (0)
KBP-5209 (0)
SKLB-1028 (0)
AZD8931 (0)
savolitinib (29)
tepotinib (24)
capmatinib (23)
TPX-0022 (8)
unecritinib (6)
CKD-702 (6)
LY2801653 (6)
gumarontinib (5)
WXSH0011 (5)
ARQ 197 (5)
REGN5093 (4)
MGCD265 (4)
AMG 102 (4)
envonalkib (3)
ABN401 (3)
BPI-9016M (2)
HQP8361 (2)
HS-10241 (2)
S95027 (2)
APL-101 (2)
AV-299 (2)
GSK1363089 (2)
DO-1 (1)
GST-HG16 (1)
JNJ-38877605 (1)
KRC-108 (1)
SGX523 (1)
SU11274 (1)
LY2875358 (1)
E7050 (1)
RG3638 (1)
AL2846 (0)
AMG 208 (0)
AMG 337 (0)
ARGX-111 (0)
ASKC202 (0)
ASLAN002 (0)
DO-2 (0)
EMD 1204831 (0)
HLX55 (0)
MRX34 (0)
PF-04217903 (0)
PHA665752 (0)
RXDX-106 (0)
S-49076 (0)
SAIT301 (0)
SAR 125844 (0)
SPH 3348 (0)
DCC-2701 (0)
BMS-794833 (0)
h224G11 (0)
XL092 (0)
›
Associations
(25)
News
Trials
VERI cancer hierarchy
Reset Filters
EGFR exon 20 insertion
Non Small Cell Lung Cancer
EGFR exon 20 insertion
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
EGFR L858R
Non Small Cell Lung Cancer
EGFR L858R
Non Small Cell Lung Cancer
amivantamab-vmjw + lazertinib
Sensitive: A1 - Approval
amivantamab-vmjw + lazertinib
Sensitive
:
A1
amivantamab-vmjw + lazertinib
Sensitive: A1 - Approval
amivantamab-vmjw + lazertinib
Sensitive
:
A1
EGFR exon 19 deletion
Non Small Cell Lung Cancer
EGFR exon 19 deletion
Non Small Cell Lung Cancer
amivantamab-vmjw + lazertinib
Sensitive: A1 - Approval
amivantamab-vmjw + lazertinib
Sensitive
:
A1
amivantamab-vmjw + lazertinib
Sensitive: A1 - Approval
amivantamab-vmjw + lazertinib
Sensitive
:
A1
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
EGFR exon 19 deletion
Lung Non-Squamous Non-Small Cell Cancer
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
EGFR L858R
Lung Non-Squamous Non-Small Cell Cancer
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
amivantamab-vmjw
Sensitive: A1 - Approval
amivantamab-vmjw
Sensitive
:
A1
EGFR exon 20 insertion
Lung Non-Squamous Non-Small Cell Cancer
EGFR exon 20 insertion
Lung Non-Squamous Non-Small Cell Cancer
amivantamab-vmjw
Sensitive: A2 - Guideline
amivantamab-vmjw
Sensitive
:
A2
amivantamab-vmjw
Sensitive: A2 - Guideline
amivantamab-vmjw
Sensitive
:
A2
EGFR mutation
Non Small Cell Lung Cancer
EGFR mutation
Non Small Cell Lung Cancer
amivantamab-vmjw + lazertinib
Sensitive: B - Late Trials
amivantamab-vmjw + lazertinib
Sensitive
:
B
amivantamab-vmjw + lazertinib
Sensitive: B - Late Trials
amivantamab-vmjw + lazertinib
Sensitive
:
B
EGFR C797S
Non Small Cell Lung Cancer
EGFR C797S
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: C2 – Inclusion Criteria
amivantamab-vmjw
Sensitive
:
C2
amivantamab-vmjw
Sensitive: C2 – Inclusion Criteria
amivantamab-vmjw
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: C2 – Inclusion Criteria
amivantamab-vmjw
Sensitive
:
C2
amivantamab-vmjw
Sensitive: C2 – Inclusion Criteria
amivantamab-vmjw
Sensitive
:
C2
MET exon 14 mutation
Non Small Cell Lung Cancer
MET exon 14 mutation
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: C2 – Inclusion Criteria
amivantamab-vmjw
Sensitive
:
C2
amivantamab-vmjw
Sensitive: C2 – Inclusion Criteria
amivantamab-vmjw
Sensitive
:
C2
EGFR exon 20 mutation
Non Small Cell Lung Cancer
EGFR exon 20 mutation
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: C2 – Inclusion Criteria
amivantamab-vmjw
Sensitive
:
C2
amivantamab-vmjw
Sensitive: C2 – Inclusion Criteria
amivantamab-vmjw
Sensitive
:
C2
EGFR mutation
Non Small Cell Lung Cancer
EGFR mutation
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: C2 – Inclusion Criteria
amivantamab-vmjw
Sensitive
:
C2
amivantamab-vmjw
Sensitive: C2 – Inclusion Criteria
amivantamab-vmjw
Sensitive
:
C2
EGFR L858R + MET positive
Non Small Cell Lung Cancer
EGFR L858R + MET positive
Non Small Cell Lung Cancer
amivantamab-vmjw + lazertinib
Sensitive: C3 – Early Trials
amivantamab-vmjw + lazertinib
Sensitive
:
C3
amivantamab-vmjw + lazertinib
Sensitive: C3 – Early Trials
amivantamab-vmjw + lazertinib
Sensitive
:
C3
EGFR exon 19 deletion + MET positive
Non Small Cell Lung Cancer
EGFR exon 19 deletion + MET positive
Non Small Cell Lung Cancer
amivantamab-vmjw + lazertinib
Sensitive: C3 – Early Trials
amivantamab-vmjw + lazertinib
Sensitive
:
C3
amivantamab-vmjw + lazertinib
Sensitive: C3 – Early Trials
amivantamab-vmjw + lazertinib
Sensitive
:
C3
EGFR S768_D770dup
Non Small Cell Lung Cancer
EGFR S768_D770dup
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: C4 – Case Studies
amivantamab-vmjw
Sensitive
:
C4
amivantamab-vmjw
Sensitive: C4 – Case Studies
amivantamab-vmjw
Sensitive
:
C4
EGFR H773delinsNPY
Non Small Cell Lung Cancer
EGFR H773delinsNPY
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: C4 – Case Studies
amivantamab-vmjw
Sensitive
:
C4
amivantamab-vmjw
Sensitive: C4 – Case Studies
amivantamab-vmjw
Sensitive
:
C4
EGFR G719A
Non Small Cell Lung Cancer
EGFR G719A
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: C4 – Case Studies
amivantamab-vmjw
Sensitive
:
C4
amivantamab-vmjw
Sensitive: C4 – Case Studies
amivantamab-vmjw
Sensitive
:
C4
EGFR L747_A750delinsP + MET D1228H + MET D1228N + MET D1228Y + MET Y1230H + MET amplification
Non Small Cell Lung Cancer
EGFR L747_A750delinsP + MET D1228H + MET D1228N + MET D1228Y + MET Y1230H + MET amplification
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: C4 – Case Studies
amivantamab-vmjw
Sensitive
:
C4
amivantamab-vmjw
Sensitive: C4 – Case Studies
amivantamab-vmjw
Sensitive
:
C4
EGFR C797S + KRAS amplification + RB1 deletion
Non Small Cell Lung Cancer
EGFR C797S + KRAS amplification + RB1 deletion
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: D – Preclinical
amivantamab-vmjw
Sensitive
:
D
amivantamab-vmjw
Sensitive: D – Preclinical
amivantamab-vmjw
Sensitive
:
D
EGFR T790M + KRAS amplification + RB1 deletion
Non Small Cell Lung Cancer
EGFR T790M + KRAS amplification + RB1 deletion
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: D – Preclinical
amivantamab-vmjw
Sensitive
:
D
amivantamab-vmjw
Sensitive: D – Preclinical
amivantamab-vmjw
Sensitive
:
D
EGFR L858R + KRAS amplification + RB1 deletion
Non Small Cell Lung Cancer
EGFR L858R + KRAS amplification + RB1 deletion
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: D – Preclinical
amivantamab-vmjw
Sensitive
:
D
amivantamab-vmjw
Sensitive: D – Preclinical
amivantamab-vmjw
Sensitive
:
D
EGFR S768dupSVD
Non Small Cell Lung Cancer
EGFR S768dupSVD
Non Small Cell Lung Cancer
amivantamab-vmjw + mobocertinib
Sensitive: D – Preclinical
amivantamab-vmjw + mobocertinib
Sensitive
:
D
amivantamab-vmjw + mobocertinib
Sensitive: D – Preclinical
amivantamab-vmjw + mobocertinib
Sensitive
:
D
EGFR A767dupASV
Non Small Cell Lung Cancer
EGFR A767dupASV
Non Small Cell Lung Cancer
amivantamab-vmjw + mobocertinib
Sensitive: D – Preclinical
amivantamab-vmjw + mobocertinib
Sensitive
:
D
amivantamab-vmjw + mobocertinib
Sensitive: D – Preclinical
amivantamab-vmjw + mobocertinib
Sensitive
:
D
^
^
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