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our Premium Content: News alerts, weekly reports and conference plannersTEST:CancerNext ®
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Company:
Konica MinoltaType:
Laboratory Developed Test
Related tests:
CancerNext analyzes 36 genes. These genes (excluding EPCAM and GREM1) are evaluated by next generation sequencing (NGS) or Sanger sequencing of all coding domains, and well into the flanking 5’ and 3’ ends of all the introns and untranslated regions.
Cancer:
Breast Cancer, Colorectal Cancer, Melanoma, Ovarian Cancer, Uterine Cancer
Gene:
APC (APC Regulator Of WNT Signaling Pathway), ATM (ATM serine/threonine kinase), AXIN2 (Axin 2), BARD1 (BRCA1 Associated RING Domain 1), BMPR1A (Bone Morphogenetic Protein Receptor Type 1A), BRCA1 (Breast cancer 1, early onset)
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APC (APC Regulator Of WNT Signaling Pathway), ATM (ATM serine/threonine kinase), AXIN2 (Axin 2), BARD1 (BRCA1 Associated RING Domain 1), BMPR1A (Bone Morphogenetic Protein Receptor Type 1A), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1), CDH1 (Cadherin 1), CDK4 (Cyclin-dependent kinase 4), CDKN2A (Cyclin Dependent Kinase Inhibitor 2A), CHEK2 (Checkpoint kinase 2), DICER1 (Dicer 1 Ribonuclease III), EPCAM (Epithelial cell adhesion molecule), HOXB13 (Homeobox B13), MLH1 (MutL homolog 1), MSH2 (MutS Homolog 2), MSH3 (MutS Homolog 3), MSH6 (MutS homolog 6), MUTYH (MutY homolog), NBN (Nibrin Nijmegen Breakage Syndrome 1 (Nibrin)), NF1 (Neurofibromin 1), PALB2 (Partner and localizer of BRCA2), PMS2 (PMS1 protein homolog 2), POLD1 (DNA Polymerase Delta 1), POLE (DNA Polymerase Epsilon), PTEN (Phosphatase and tensin homolog), RAD51C (RAD51 paralog C), RAD51D (RAD51 paralog D), RECQL (RecQ Like Helicase), SMAD4 (SMAD family member 4), SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily A, member 4), STK11 (Serine/threonine kinase 11), TP53 (Tumor protein P53)
Method:
Next-Generation Sequencing (NGS)
