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our Premium Content: News alerts, weekly reports and conference plannersTEST:BrainTumorNext®
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News alerts, weekly reports and conference planners
Company:
Konica MinoltaType:
Laboratory Developed Test
Related tests:
BrainTumorNext is a next generation sequencing panel that simultaneously analyzes 29 genes associated with increased risk for brain tumors and other cancers/tumors. It can detect >99.9% of described mutations in the included genes, when present. Testing to be considered in Early-onset brain tumor(s) (diagnosed <50 years of age), Multiple primary cancers in one person (e.g. brain tumor and colorectal cancer), Multiple close relatives on the same side of the family with brain tumors or A family history of a mutation in a gene that predisposes to brain tumors.
Cancer:
Brain Cancer, Colorectal Cancer
Gene:
ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), CDKN1B (Cyclin dependent kinase inhibitor 1B), CDKN2A (Cyclin-dependent kinase inhibitor 2A), EPCAM (Epithelial cell adhesion molecule), MLH1 (MutL homolog 1)
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ALK (Anaplastic lymphoma kinase), APC (APC Regulator Of WNT Signaling Pathway), CDKN1B (Cyclin dependent kinase inhibitor 1B), CDKN2A (Cyclin-dependent kinase inhibitor 2A), EPCAM (Epithelial cell adhesion molecule), MLH1 (MutL homolog 1), MSH2 (MutS Homolog 2), MSH6 (MutS homolog 6), NBN (Nibrin Nijmegen Breakage Syndrome 1 (Nibrin)), NF1 (Neurofibromin 1), NF2 (Neurofibromin 2), PMS2 (PMS1 protein homolog 2), PTCH1 (Patched 1), PTEN (Phosphatase and tensin homolog), SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily A, member 4), TP53 (Tumor protein P53), TSC1 (TSC complex subunit 1), TSC2 (TSC complex subunit 2), VHL (von Hippel-Lindau tumor suppressor)
Method:
Next-Generation Sequencing (NGS)
