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our Premium Content: News alerts, weekly reports and conference plannersTEST:BRCANext®
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Company:
Konica MinoltaType:
Laboratory Developed Test
Related tests:
BRCANext analyzes 19 genes (listed above). These genes (excluding EPCAM) are evaluated by next generation sequencing (NGS) or Sanger sequencing of all coding domains, and well into the flanking 5’ and 3’ ends of all the introns and untranslated regions.
Cancer:
Breast Cancer, Gynecologic Cancers, Male Breast Cancer, Ovarian Cancer, Pancreatic Cancer, Prostate Cancer
Gene:
ATM (ATM serine/threonine kinase), BARD1 (BRCA1 Associated RING Domain 1), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1), CDH1 (Cadherin 1)
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ATM (ATM serine/threonine kinase), BARD1 (BRCA1 Associated RING Domain 1), BRCA1 (Breast cancer 1, early onset), BRCA2 (Breast cancer 2, early onset), BRIP1 (BRCA1 Interacting Protein C-terminal Helicase 1), CDH1 (Cadherin 1), CHEK2 (Checkpoint kinase 2), EPCAM (Epithelial cell adhesion molecule), MLH1 (MutL homolog 1), MSH2 (MutS Homolog 2), MSH6 (MutS homolog 6), NF1 (Neurofibromin 1), PALB2 (Partner and localizer of BRCA2), PMS2 (PMS1 protein homolog 2), PTEN (Phosphatase and tensin homolog), RAD51C (RAD51 paralog C), RAD51D (RAD51 paralog D), STK11 (Serine/threonine kinase 11), TP53 (Tumor protein P53)
Method:
Next-Generation Sequencing (NGS)
