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BIOMARKER:

BRAF V600E + KRAS G12R

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Entrez ID:

Related biomarkers:

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BRAF V600E (255)

KRAS mutation (239)

KRAS G12C (159)

BRAF mutation (129)

BRAF V600 (105)

KRAS wild-type (26)

BRAF V600K (25)

BRAF wild-type (25)

RAS wild-type (17)

KRAS mutation + STK11 mutation (8)

KRAS exon 2 mutation (7)

RAS wild-type + BRAF wild-type (7)

TP53 mutation + KRAS mutation (6)

BRAF V600E + RNF43 mutation (6)

EGFR mutation + BRAF V600E (6)

KRAS G12C + STK11 mutation (5)

EGFR mutation + KRAS mutation (4)

BRAF V600E + PIK3CA mutation (4)

NRAS mutation + BRAF mutation (4)

KRAS G12C + TP53 mutation (3)

KRAS G12D + STK11 mutation (3)

BRAF T1799A (3)

BRAF V600E + TERT mutation (3)

BRAF delNVTAP (3)

NRAS Q61K + BRAF V600E (3)

TERT mutation + BRAF V600E (3)

EGFR T790M + KRAS mutation (2)

EGFR V802I + KRAS mutation (2)

KEAP1 mutation + KRAS mutation (2)

KRAS G12C + KEAP1 mutation (2)

KRAS G12D + KRAS G12V (2)

KRAS G13D + BRAF mutation (2)

KRAS exon 12 mutation (2)

KRAS exon 2 wild-type (2)

KRAS exon 3 mutation (2)

KRAS exon 4 mutation (2)

KRAS mutation + EGFR wild-type (2)

KRAS mutation + STK11 mutation + KEAP1 mutation (2)

KRAS mutation + TP53 wild-type (2)

PIK3CA mutation + KRAS mutation (2)

STK11 mutation + KEAP1 mutation + KRAS G12C (2)

BRAF V600E + MAP2K1 I111S (2)

BRAF mutation + MEK1 P124L (2)

BRAF mutation + NF1 mutation (2)

EGFR mutation + BRAF V600 (2)

IDH1 wild-type + BRAF mutation (2)

MYD88 L265P + BRAF V600E (2)

NRAS G12C + BRAF mutation (2)

ALK rearrangement + EGFR D761N + KRAS V14I (1)

ALK rearrangement + KRAS mutation (1)

APC mutation + KRAS mutation (1)

ARID1A mutation+ KRAS G12C (1)

DICER1 A1690Gfs*9 + DICER1 E1813Q + KRAS G12L (1)

EGFR T790M + KRAS G12V (1)

KIR2DS4 mutation + KRAS mutation (1)

KRAS G12A + BRAF D549N (1)

KRAS G12C + ATM wild-type (1)

KRAS G12C + KRAS G12V (1)

KRAS G12C + SMARCA4 wild-type (1)

KRAS G12D + DNMT3A C559fsX (1)

KRAS G12V + BRAF V600E (1)

KRAS G12V + STK11 mutation (1)

KRAS G12V + TP53 mutation + APC mutation (1)

KRAS G61H + KRAS G12A (1)

KRAS codon 12 mutation + KRAS codon 13 mutation + EGFR mutation (1)

KRAS exon 13 mutation (1)

KRAS mutation + ATM mutation (1)

KRAS mutation + KEAP1 mutation (1)

KRAS mutation + SMARCA4 mutation (1)

KRAS mutation + STK11 deletion + KEAP1 deletion (1)

KRAS mutation + STK11 mutation + TP53 mutation (1)

KRAS mutation + U2AF1 mutation (1)

KRAS mutation + KMT2C mutation (1)

MAP2K1 G128D + KRAS mutation (1)

MET exon 14 mutation + KRAS G12A (1)

NF1 L581Ffs*6 + KRAS A146P + NRAS Q61K + TP53 R175H + PD-L1 T290M (1)

PIK3CA mutation + PTEN mutation + KRAS mutation (1)

PIK3CA wild-type + KRAS wild-type (1)

PTPN11 mutation + KRAS wild-type (1)

STK11 mutation + KEAP1 mutation + KRAS wild-type (1)

AKT1 E17K + BRAF V600 (1)

BRAF 486_490 del (1)

BRAF G466E + NF1 Y2285fs*5 + NF1 Y2640fs*3 + TP53 D281Y (1)

BRAF G466V + KIT K509Q (1)

BRAF N486-P490del + TP53 V157G (1)

BRAF V600 wild-type (1)

BRAF V600DK601del (1)

BRAF V600E + BRAF G469A + BRAF G469V (1)

BRAF V600E + BRAF K601_W604del (1)

BRAF V600E + BRAF L514V (1)

BRAF V600E + BRAF V600K (1)

BRAF V600E + MSI-H/dMMR (1)

BRAF V600E + TERT E441del + RET N579K + EZH2 D154E + CDK4 S259L (1)

BRAF V600_K601delinsE (1)

BRAF mutation + EGFR mutation (1)

BRAF mutation + MAP2K1 mutation (1)

BRAF mutation + RAS mutation (1)

BRAF mutation + TERT −124C>T (1)

BRAF mutation + TERT −138CC>TT (1)

BRAF mutation + TERT −139CC>TT (1)

BRAF mutation + TERT −146C>T (1)

BRAF mutation + TET2 mutation (1)

BRAF mutation + TP53 mutation (1)

BRAF rearrangement (1)

BRAF wild-type + NRAS wild-type (1)

EGFR T790M + BRAF V600E (1)

EGFR exon 19 deletion + BRAF V600E (1)

EGFR mutation + BRAF G469A (1)

EGFR mutation + BRAF mutation + TP53 mutation (1)

MAP2K1 V211D + BRAF mutation (1)

NRAS G12C + BRAF V600E + BRAF V600D (1)

NRAS G13D + BRAF V600E (1)

RAS wild-type + BRAF wild-type + MAP2K1 N57K (1)

ROS1 rearrangement + BRAF V600E (1)

TERT promoter mutation + BRAF V600 (1)

BRAF V600E + KRAS G12D (0)

CDKN2A mutation + CDKN2B mutation + KRAS mutation (0)

CDKN2A mutation + KRAS mutation (0)

KRAS mutation + TP53 mutation (0)

BRAF V600E + TERT mutation (0)

BRAF V600E + MAP2K1 P124S (0)

BRAF exon 11 mutation (0)

BRAF exon 15 mutation (0)

CDKN2A mutation + BRAF V600E (0)

BRAF V600E (255)

KRAS mutation (239)

KRAS G12C (159)

BRAF mutation (129)

BRAF V600 (105)

KRAS wild-type (26)

BRAF V600K (25)

BRAF wild-type (25)

RAS wild-type (17)

KRAS mutation + STK11 mutation (8)

KRAS exon 2 mutation (7)

RAS wild-type + BRAF wild-type (7)

TP53 mutation + KRAS mutation (6)

BRAF V600E + RNF43 mutation (6)

EGFR mutation + BRAF V600E (6)

KRAS G12C + STK11 mutation (5)

EGFR mutation + KRAS mutation (4)

BRAF V600E + PIK3CA mutation (4)

NRAS mutation + BRAF mutation (4)

KRAS G12C + TP53 mutation (3)

KRAS G12D + STK11 mutation (3)

BRAF T1799A (3)

BRAF V600E + TERT mutation (3)

BRAF delNVTAP (3)

NRAS Q61K + BRAF V600E (3)

TERT mutation + BRAF V600E (3)

EGFR T790M + KRAS mutation (2)

EGFR V802I + KRAS mutation (2)

KEAP1 mutation + KRAS mutation (2)

KRAS G12C + KEAP1 mutation (2)

KRAS G12D + KRAS G12V (2)

KRAS G13D + BRAF mutation (2)

KRAS exon 12 mutation (2)

KRAS exon 2 wild-type (2)

KRAS exon 3 mutation (2)

KRAS exon 4 mutation (2)

KRAS mutation + EGFR wild-type (2)

KRAS mutation + STK11 mutation + KEAP1 mutation (2)

KRAS mutation + TP53 wild-type (2)

PIK3CA mutation + KRAS mutation (2)

STK11 mutation + KEAP1 mutation + KRAS G12C (2)

BRAF V600E + MAP2K1 I111S (2)

BRAF mutation + MEK1 P124L (2)

BRAF mutation + NF1 mutation (2)

EGFR mutation + BRAF V600 (2)

IDH1 wild-type + BRAF mutation (2)

MYD88 L265P + BRAF V600E (2)

NRAS G12C + BRAF mutation (2)

ALK rearrangement + EGFR D761N + KRAS V14I (1)

ALK rearrangement + KRAS mutation (1)

APC mutation + KRAS mutation (1)

ARID1A mutation+ KRAS G12C (1)

DICER1 A1690Gfs*9 + DICER1 E1813Q + KRAS G12L (1)

EGFR T790M + KRAS G12V (1)

KIR2DS4 mutation + KRAS mutation (1)

KRAS G12A + BRAF D549N (1)

KRAS G12C + ATM wild-type (1)

KRAS G12C + KRAS G12V (1)

KRAS G12C + SMARCA4 wild-type (1)

KRAS G12D + DNMT3A C559fsX (1)

KRAS G12V + BRAF V600E (1)

KRAS G12V + STK11 mutation (1)

KRAS G12V + TP53 mutation + APC mutation (1)

KRAS G61H + KRAS G12A (1)

KRAS codon 12 mutation + KRAS codon 13 mutation + EGFR mutation (1)

KRAS exon 13 mutation (1)

KRAS mutation + ATM mutation (1)

KRAS mutation + KEAP1 mutation (1)

KRAS mutation + SMARCA4 mutation (1)

KRAS mutation + STK11 deletion + KEAP1 deletion (1)

KRAS mutation + STK11 mutation + TP53 mutation (1)

KRAS mutation + U2AF1 mutation (1)

KRAS mutation + KMT2C mutation (1)

MAP2K1 G128D + KRAS mutation (1)

MET exon 14 mutation + KRAS G12A (1)

NF1 L581Ffs*6 + KRAS A146P + NRAS Q61K + TP53 R175H + PD-L1 T290M (1)

PIK3CA mutation + PTEN mutation + KRAS mutation (1)

PIK3CA wild-type + KRAS wild-type (1)

PTPN11 mutation + KRAS wild-type (1)

STK11 mutation + KEAP1 mutation + KRAS wild-type (1)

AKT1 E17K + BRAF V600 (1)

BRAF 486_490 del (1)

BRAF G466E + NF1 Y2285fs*5 + NF1 Y2640fs*3 + TP53 D281Y (1)

BRAF G466V + KIT K509Q (1)

BRAF N486-P490del + TP53 V157G (1)

BRAF V600 wild-type (1)

BRAF V600DK601del (1)

BRAF V600E + BRAF G469A + BRAF G469V (1)

BRAF V600E + BRAF K601_W604del (1)

BRAF V600E + BRAF L514V (1)

BRAF V600E + BRAF V600K (1)

BRAF V600E + MSI-H/dMMR (1)

BRAF V600E + TERT E441del + RET N579K + EZH2 D154E + CDK4 S259L (1)

BRAF V600_K601delinsE (1)

BRAF mutation + EGFR mutation (1)

BRAF mutation + MAP2K1 mutation (1)

BRAF mutation + RAS mutation (1)

BRAF mutation + TERT −124C>T (1)

BRAF mutation + TERT −138CC>TT (1)

BRAF mutation + TERT −139CC>TT (1)

BRAF mutation + TERT −146C>T (1)

BRAF mutation + TET2 mutation (1)

BRAF mutation + TP53 mutation (1)

BRAF rearrangement (1)

BRAF wild-type + NRAS wild-type (1)

EGFR T790M + BRAF V600E (1)

EGFR exon 19 deletion + BRAF V600E (1)

EGFR mutation + BRAF G469A (1)

EGFR mutation + BRAF mutation + TP53 mutation (1)

MAP2K1 V211D + BRAF mutation (1)

NRAS G12C + BRAF V600E + BRAF V600D (1)

NRAS G13D + BRAF V600E (1)

RAS wild-type + BRAF wild-type + MAP2K1 N57K (1)

ROS1 rearrangement + BRAF V600E (1)

TERT promoter mutation + BRAF V600 (1)

BRAF V600E + KRAS G12D (0)

CDKN2A mutation + CDKN2B mutation + KRAS mutation (0)

CDKN2A mutation + KRAS mutation (0)

KRAS mutation + TP53 mutation (0)

BRAF V600E + TERT mutation (0)

BRAF V600E + MAP2K1 P124S (0)

BRAF exon 11 mutation (0)

BRAF exon 15 mutation (0)

CDKN2A mutation + BRAF V600E (0)

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BRAF V600E + KRAS G12R

Colorectal Cancer

Resistant: C4 – Case Studies

Resistant: C4 – Case Studies