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BIOMARKER:

KRAS G12D

i
Other names: KRAS, KRAS1, KRAS2, Kirsten rat sarcoma viral oncogene homolog
Entrez ID:
Related biomarkers:
KRAS G12D
CRC
cetuximab
Resistant: B - Late Trials
KRAS G12D
CRC
panitumumab
Resistant: B - Late Trials
KRAS G12D
NSCLC
osimertinib
Resistant: C3 – Early Trials
KRAS G12D
CRC
cobimetinib + SAR442720
Sensitive: C3 – Early Trials
KRAS G12D
Ovarian Serous Adenocarcinoma
VS-6766 + VS-6063
Sensitive: C3 – Early Trials
KRAS G12D
Biliary Tract Cancer
selumetinib
Sensitive: C3 – Early Trials
KRAS G12D
HCC
sorafenib + BAY86-9766
Sensitive: C3 – Early Trials
KRAS G12D
Pancreatic Cancer
entrectinib
Sensitive: C3 – Early Trials
KRAS G12D
CRC
bevacizumab + PCM-075
Sensitive: C3 – Early Trials
KRAS G12D
Pancreatic Cancer
ASTX029
Sensitive: C3 – Early Trials
KRAS G12D
NSCLC
Immunotherapy
Sensitive: C3 – Early Trials
KRAS G12D
CRC
FOLFOX
Resistant: C3 – Early Trials
KRAS G12D
Gallbladder Cancer
pembrolizumab
Sensitive: C4 – Case Studies
KRAS G12D
CRC
regorafenib
Sensitive: C4 – Case Studies
KRAS G12D
Pancreatic Cancer
MK-2206
Sensitive: C4 – Case Studies
KRAS G12D
Lung Cancer
KS-58
Sensitive: D – Preclinical
KRAS G12D
NSCLC
IPI-504
Sensitive: D – Preclinical
KRAS G12D
Pancreatic Cancer
KS-58
Sensitive: D – Preclinical
KRAS G12D
CRC
MRTX1133
Sensitive: D – Preclinical
KRAS G12D
Pancreatic Cancer
MRTX1133
Sensitive: D – Preclinical
KRAS G12D
Pancreatic Cancer
BCN057
Sensitive: D – Preclinical
KRAS G12D
Cholangiocarcinoma
ponatinib
Sensitive: D – Preclinical
KRAS G12D
Cholangiocarcinoma
bosutinib
Sensitive: D – Preclinical
KRAS G12D
Cholangiocarcinoma
AZD0530
Sensitive: D – Preclinical
KRAS G12D
Cholangiocarcinoma
dasatinib
Sensitive: D – Preclinical
KRAS G12D
Ovarian Cancer
PD-0325901 + PF-04691502
Sensitive: D – Preclinical
KRAS G12D
Ovarian Cancer
PF-04691502
Sensitive: D – Preclinical
KRAS G12D
NSCLC
selumetinib + CYT 387
Sensitive: D – Preclinical
KRAS G12D
Lung Cancer
selumetinib + ABT 263
Sensitive: D – Preclinical
KRAS G12D
CRC
sunitinib
Resistant: D – Preclinical
KRAS G12D
CRC
cetuximab + vemurafenib
Resistant: D – Preclinical
KRAS G12D
CMML
trametinib
Resistant: D – Preclinical
KRAS G12D
CMML
selumetinib
Resistant: D – Preclinical
KRAS G12D
CRC
palbociclib + MSC2504877
Resistant: D – Preclinical