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BIOMARKER:
KRAS G12D
i
Other names:
KRAS, KRAS1, KRAS2, Kirsten rat sarcoma viral oncogene homolog
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Entrez ID:
3845
Related biomarkers:
Expression
Mutation
CNA
Others
‹
›
Related tests:
therascreen® KRAS RGQ PCR Kit (5)
therascreen® KRAS RGQ PCR Kit (5)
Associations
News
Trials
VERI cancer hierarchy
Reset Filters
KRAS G12D
Colorectal Cancer
KRAS G12D
Colorectal Cancer
cetuximab
Resistant: B - Late Trials
cetuximab
Resistant
:
B
cetuximab
Resistant: B - Late Trials
cetuximab
Resistant
:
B
KRAS G12D
Colorectal Cancer
KRAS G12D
Colorectal Cancer
panitumumab
Resistant: B - Late Trials
panitumumab
Resistant
:
B
panitumumab
Resistant: B - Late Trials
panitumumab
Resistant
:
B
KRAS G12D
Colorectal Cancer
KRAS G12D
Colorectal Cancer
MRTX1133
Sensitive: C2 – Inclusion Criteria
MRTX1133
Sensitive
:
C2
MRTX1133
Sensitive: C2 – Inclusion Criteria
MRTX1133
Sensitive
:
C2
KRAS G12D
Pancreatic Cancer
KRAS G12D
Pancreatic Cancer
MRTX1133
Sensitive: C2 – Inclusion Criteria
MRTX1133
Sensitive
:
C2
MRTX1133
Sensitive: C2 – Inclusion Criteria
MRTX1133
Sensitive
:
C2
KRAS G12D
Non Small Cell Lung Cancer
KRAS G12D
Non Small Cell Lung Cancer
RMC-9805
Sensitive: C2 – Inclusion Criteria
RMC-9805
Sensitive
:
C2
RMC-9805
Sensitive: C2 – Inclusion Criteria
RMC-9805
Sensitive
:
C2
KRAS G12D
Non Small Cell Lung Cancer
KRAS G12D
Non Small Cell Lung Cancer
osimertinib
Resistant: C3 – Early Trials
osimertinib
Resistant
:
C3
osimertinib
Resistant: C3 – Early Trials
osimertinib
Resistant
:
C3
KRAS G12D
Colorectal Cancer
KRAS G12D
Colorectal Cancer
cobimetinib + RMC-4630
Sensitive: C3 – Early Trials
cobimetinib + RMC-4630
Sensitive
:
C3
cobimetinib + RMC-4630
Sensitive: C3 – Early Trials
cobimetinib + RMC-4630
Sensitive
:
C3
KRAS G12D
Ovarian Serous Adenocarcinoma
KRAS G12D
Ovarian Serous Adenocarcinoma
VS-6766 + VS-6063
Sensitive: C3 – Early Trials
VS-6766 + VS-6063
Sensitive
:
C3
VS-6766 + VS-6063
Sensitive: C3 – Early Trials
VS-6766 + VS-6063
Sensitive
:
C3
KRAS G12D
Biliary Tract Cancer
KRAS G12D
Biliary Tract Cancer
selumetinib
Sensitive: C3 – Early Trials
selumetinib
Sensitive
:
C3
selumetinib
Sensitive: C3 – Early Trials
selumetinib
Sensitive
:
C3
KRAS G12D
Hepatocellular Cancer
KRAS G12D
Hepatocellular Cancer
sorafenib + BAY86-9766
Sensitive: C3 – Early Trials
sorafenib + BAY86-9766
Sensitive
:
C3
sorafenib + BAY86-9766
Sensitive: C3 – Early Trials
sorafenib + BAY86-9766
Sensitive
:
C3
KRAS G12D
Pancreatic Cancer
KRAS G12D
Pancreatic Cancer
entrectinib
Sensitive: C3 – Early Trials
entrectinib
Sensitive
:
C3
entrectinib
Sensitive: C3 – Early Trials
entrectinib
Sensitive
:
C3
KRAS G12D
Colorectal Cancer
KRAS G12D
Colorectal Cancer
bevacizumab + PCM-075
Sensitive: C3 – Early Trials
bevacizumab + PCM-075
Sensitive
:
C3
bevacizumab + PCM-075
Sensitive: C3 – Early Trials
bevacizumab + PCM-075
Sensitive
:
C3
KRAS G12D
Pancreatic Cancer
KRAS G12D
Pancreatic Cancer
ASTX029
Sensitive: C3 – Early Trials
ASTX029
Sensitive
:
C3
ASTX029
Sensitive: C3 – Early Trials
ASTX029
Sensitive
:
C3
KRAS G12D
Non Small Cell Lung Cancer
KRAS G12D
Non Small Cell Lung Cancer
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
Immunotherapy
Sensitive: C3 – Early Trials
Immunotherapy
Sensitive
:
C3
KRAS G12D
Colorectal Cancer
KRAS G12D
Colorectal Cancer
Resistant: C3 – Early Trials
Resistant
:
C3
Resistant: C3 – Early Trials
Resistant
:
C3
KRAS G12D
Non Small Cell Lung Cancer
KRAS G12D
Non Small Cell Lung Cancer
PD-L1 inhibitor
Resistant: C3 – Early Trials
PD-L1 inhibitor
Resistant
:
C3
PD-L1 inhibitor
Resistant: C3 – Early Trials
PD-L1 inhibitor
Resistant
:
C3
KRAS G12D
Non Small Cell Lung Cancer
KRAS G12D
Non Small Cell Lung Cancer
PD1 inhibitor
Resistant: C3 – Early Trials
PD1 inhibitor
Resistant
:
C3
PD1 inhibitor
Resistant: C3 – Early Trials
PD1 inhibitor
Resistant
:
C3
KRAS G12D
Non Small Cell Lung Cancer
KRAS G12D
Non Small Cell Lung Cancer
nivolumab + rigosertib
Sensitive: C3 – Early Trials
nivolumab + rigosertib
Sensitive
:
C3
nivolumab + rigosertib
Sensitive: C3 – Early Trials
nivolumab + rigosertib
Sensitive
:
C3
KRAS G12D
Non Small Cell Lung Cancer
KRAS G12D
Non Small Cell Lung Cancer
regorafenib
Sensitive: C3 – Early Trials
regorafenib
Sensitive
:
C3
regorafenib
Sensitive: C3 – Early Trials
regorafenib
Sensitive
:
C3
KRAS G12D
Pancreatic Ductal Adenocarcinoma
KRAS G12D
Pancreatic Ductal Adenocarcinoma
gemcitabine + paclitaxel
Resistant: C3 – Early Trials
gemcitabine + paclitaxel
Resistant
:
C3
gemcitabine + paclitaxel
Resistant: C3 – Early Trials
gemcitabine + paclitaxel
Resistant
:
C3
KRAS G12D
Gallbladder Cancer
KRAS G12D
Gallbladder Cancer
pembrolizumab
Sensitive: C4 – Case Studies
pembrolizumab
Sensitive
:
C4
pembrolizumab
Sensitive: C4 – Case Studies
pembrolizumab
Sensitive
:
C4
KRAS G12D
Colorectal Cancer
KRAS G12D
Colorectal Cancer
regorafenib
Sensitive: C4 – Case Studies
regorafenib
Sensitive
:
C4
regorafenib
Sensitive: C4 – Case Studies
regorafenib
Sensitive
:
C4
KRAS G12D
Pancreatic Cancer
KRAS G12D
Pancreatic Cancer
MK-2206
Sensitive: C4 – Case Studies
MK-2206
Sensitive
:
C4
MK-2206
Sensitive: C4 – Case Studies
MK-2206
Sensitive
:
C4
KRAS G12D
Ovarian Serous Adenocarcinoma
KRAS G12D
Ovarian Serous Adenocarcinoma
binimetinib + PF-07284892
Sensitive: C4 – Case Studies
binimetinib + PF-07284892
Sensitive
:
C4
binimetinib + PF-07284892
Sensitive: C4 – Case Studies
binimetinib + PF-07284892
Sensitive
:
C4
KRAS G12D
Lung Cancer
KRAS G12D
Lung Cancer
KS-58
Sensitive: D – Preclinical
KS-58
Sensitive
:
D
KS-58
Sensitive: D – Preclinical
KS-58
Sensitive
:
D
KRAS G12D
Non Small Cell Lung Cancer
KRAS G12D
Non Small Cell Lung Cancer
IPI-504
Sensitive: D – Preclinical
IPI-504
Sensitive
:
D
IPI-504
Sensitive: D – Preclinical
IPI-504
Sensitive
:
D
KRAS G12D
Pancreatic Cancer
KRAS G12D
Pancreatic Cancer
KS-58
Sensitive: D – Preclinical
KS-58
Sensitive
:
D
KS-58
Sensitive: D – Preclinical
KS-58
Sensitive
:
D
KRAS G12D
Pancreatic Cancer
KRAS G12D
Pancreatic Cancer
BCN057
Sensitive: D – Preclinical
BCN057
Sensitive
:
D
BCN057
Sensitive: D – Preclinical
BCN057
Sensitive
:
D
KRAS G12D
Cholangiocarcinoma
KRAS G12D
Cholangiocarcinoma
ponatinib
Sensitive: D – Preclinical
ponatinib
Sensitive
:
D
ponatinib
Sensitive: D – Preclinical
ponatinib
Sensitive
:
D
KRAS G12D
Cholangiocarcinoma
KRAS G12D
Cholangiocarcinoma
bosutinib
Sensitive: D – Preclinical
bosutinib
Sensitive
:
D
bosutinib
Sensitive: D – Preclinical
bosutinib
Sensitive
:
D
KRAS G12D
Cholangiocarcinoma
KRAS G12D
Cholangiocarcinoma
AZD0530
Sensitive: D – Preclinical
AZD0530
Sensitive
:
D
AZD0530
Sensitive: D – Preclinical
AZD0530
Sensitive
:
D
KRAS G12D
Cholangiocarcinoma
KRAS G12D
Cholangiocarcinoma
dasatinib
Sensitive: D – Preclinical
dasatinib
Sensitive
:
D
dasatinib
Sensitive: D – Preclinical
dasatinib
Sensitive
:
D
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