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    DRUG:

    MTX-211

    i
    Other names: MTX-211, MTX211, MTX 211
    Associations

    News

    Trials
    Company:
    Mekanistic Therap
    Drug class:
    EGFR inhibitor, PI3K inhibitor
    Related drugs:
    Associations

    News

    Trials
    1year
    MTX-211 Inhibits GSH Synthesis through Keap1/NRF2/GCLM Axis and Exerts Antitumor Effects in Bladder Cancer. (PubMed, Int J Mol Sci)
    This study provided evidence that MTX-211 effectively inhibited BLCA cell proliferation via depleting GSH levels through Keap1/NRF2/GCLM signaling pathway. Thus, MTX-211 could be a promising therapeutic agent for cancer.
    Journal
    |
    KEAP1 (Kelch Like ECH Associated Protein 1)
    |
    MTX-211