Associations - pictilisib (GDC-0941)

BRAF V600E	Melanoma	BRAF V600E	Melanoma	GDC-0941 Sensitive: C3 – Early Trials GDC-0941 Sensitive : C3	GDC-0941 Sensitive: C3 – Early Trials GDC-0941 Sensitive : C3
MMP11 overexpression	Breast Cancer	MMP11 overexpression	Breast Cancer	GDC-0941 + AZ 960 Sensitive: C3 – Early Trials GDC-0941 + AZ 960 Sensitive : C3	GDC-0941 + AZ 960 Sensitive: C3 – Early Trials GDC-0941 + AZ 960 Sensitive : C3
ER positive	HER2 Negative Breast Cancer	ER positive	HER2 Negative Breast Cancer	GDC-0941 Sensitive: C3 – Early Trials GDC-0941 Sensitive : C3	GDC-0941 Sensitive: C3 – Early Trials GDC-0941 Sensitive : C3
PIK3CA mutation	Non Small Cell Lung Cancer	PIK3CA mutation	Non Small Cell Lung Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
KRAS mutation	Non Small Cell Lung Cancer	KRAS mutation	Non Small Cell Lung Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PIK3CA mutation + KRAS mutation	Endometrial Cancer	PIK3CA mutation + KRAS mutation	Endometrial Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PTEN deletion	Non Small Cell Lung Cancer	PTEN deletion	Non Small Cell Lung Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PIK3CA amplification	Non Small Cell Lung Cancer	PIK3CA amplification	Non Small Cell Lung Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PTEN mutation	Endometrial Cancer	PTEN mutation	Endometrial Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PIK3CA mutation + PTEN mutation + KRAS mutation	Endometrial Cancer	PIK3CA mutation + PTEN mutation + KRAS mutation	Endometrial Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PIK3CA mutation	Endometrial Cancer	PIK3CA mutation	Endometrial Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PIK3CA E545K	Breast Cancer	PIK3CA E545K	Breast Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PIK3CA K111N	Breast Cancer	PIK3CA K111N	Breast Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PIK3CA H1047R	Breast Cancer	PIK3CA H1047R	Breast Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PIK3CA H1047L	Breast Cancer	PIK3CA H1047L	Breast Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PIK3CA C420R	Breast Cancer	PIK3CA C420R	Breast Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PIK3CA mutation + HER-2 amplification	Breast Cancer	PIK3CA mutation + HER-2 amplification	Breast Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PIK3CA mutation + PTEN deletion	Breast Cancer	PIK3CA mutation + PTEN deletion	Breast Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
HER-2 amplification + PTEN deletion	Breast Cancer	HER-2 amplification + PTEN deletion	Breast Cancer	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D
PIK3CA E545K	Squamous Cell Carcinoma of Head and Neck	PIK3CA E545K	Squamous Cell Carcinoma of Head and Neck	GDC-0941 Resistant: D – Preclinical GDC-0941 Resistant : D	GDC-0941 Resistant: D – Preclinical GDC-0941 Resistant : D
PIK3CA H1047R	Squamous Cell Carcinoma of Head and Neck	PIK3CA H1047R	Squamous Cell Carcinoma of Head and Neck	GDC-0941 Resistant: D – Preclinical GDC-0941 Resistant : D	GDC-0941 Resistant: D – Preclinical GDC-0941 Resistant : D
DNMT3A deletion	Acute Myelogenous Leukemia	DNMT3A deletion	Acute Myelogenous Leukemia	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D	GDC-0941 Sensitive: D – Preclinical GDC-0941 Sensitive : D

pictilisib (GDC-0941)

Associations
(22)

Associations
(22)

pictilisib (GDC-0941)

Associations(22)

Associations(22)

Associations
(22)

Associations
(22)