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BIOMARKER:
MYD88 L265P + BRAF V600E
i
Other names:
MYD88, MYD88 Innate Immune Signal Transduction Adaptor, Myeloid Differentiation Primary Response Protein MyD88, Myeloid Differentiation Primary Response Gene (88), Myeloid Differentiation Primary Response 88, Mutant Myeloid Differentiation Primary Response 88, MYD88D, BRAF, B-raf proto-oncogene, B-raf proto-oncogene, Serine/threonine kinase, V-Raf murine sarcoma viral oncogene homolog B, Serine/threonine-protein kinase B-Raf, Proto-oncogene B-Raf, BRAF1, RAFB1, B-raf proto-oncogene Serine/threon
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Entrez ID:
673
;
4615
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
BRAF V600E (255)
BRAF mutation (129)
BRAF V600 (106)
BRAF V600K (25)
BRAF wild-type (25)
MYD88 mutation (19)
MYD88 L265P (13)
BRAF G469V (7)
BRAF K601E (7)
RAS wild-type + BRAF wild-type (7)
BRAF D594G (6)
BRAF V600E + RNF43 mutation (6)
EGFR mutation + BRAF V600E (6)
BRAF G466V (4)
BRAF V600E + PIK3CA mutation (4)
BRAF V600G (4)
NRAS mutation + BRAF mutation (4)
BRAF D549G (3)
BRAF G469A (3)
BRAF G469E (3)
BRAF L597Q (3)
BRAF L597R (3)
BRAF T1799A (3)
BRAF V595E (3)
BRAF V600E + TERT mutation (3)
BRAF V600R (3)
BRAF delNVTAP (3)
NRAS Q61K + BRAF V600E (3)
TERT mutation + BRAF V600E (3)
BRAF G466A (2)
BRAF L485W (2)
BRAF V600D (2)
BRAF V600E + MAP2K1 I111S (2)
BRAF V600M (2)
BRAF mutation + MEK1 P124L (2)
BRAF mutation + NF1 mutation (2)
BRAF rearrangement (2)
EGFR mutation + BRAF V600 (2)
IDH1 wild-type + BRAF mutation (2)
KRAS G13D + BRAF mutation (2)
NRAS G12C + BRAF mutation (2)
MYD88 L265P + CD79B mutation (2)
MYD88 mutation + CXCR4 mutation (2)
AKT1 E17K + BRAF V600 (1)
BRAF 486_490 del (1)
BRAF D594N (1)
BRAF G464 (1)
BRAF G464E (1)
BRAF G466E + NF1 Y2285fs*5 + NF1 Y2640fs*3 + TP53 D281Y (1)
BRAF G466V + KIT K509Q (1)
BRAF G469R (1)
BRAF G469S (1)
BRAF G596V (1)
BRAF L505H (1)
BRAF L597K (1)
BRAF L597S (1)
BRAF N486-P490del + TP53 V157G (1)
BRAF S365L (1)
BRAF T599 (1)
BRAF V600 wild-type (1)
BRAF V600DK601del (1)
BRAF V600E + BRAF G469A + BRAF G469V (1)
BRAF V600E + BRAF K601_W604del (1)
BRAF V600E + BRAF L514V (1)
BRAF V600E + BRAF V600K (1)
BRAF V600E + KRAS G12R (1)
BRAF V600E + MSI-H/dMMR (1)
BRAF V600E + TERT E441del + RET N579K + EZH2 D154E + CDK4 S259L (1)
BRAF V600_K601delinsE (1)
BRAF Y472C (1)
BRAF mutation + EGFR mutation (1)
BRAF mutation + MAP2K1 mutation (1)
BRAF mutation + RAS mutation (1)
BRAF mutation + TERT −124C>T (1)
BRAF mutation + TERT −138CC>TT (1)
BRAF mutation + TERT −139CC>TT (1)
BRAF mutation + TERT −146C>T (1)
BRAF mutation + TET2 mutation (1)
BRAF mutation + TP53 mutation (1)
BRAF wild-type + NRAS wild-type (1)
EGFR T790M + BRAF V600E (1)
EGFR exon 19 deletion + BRAF V600E (1)
EGFR mutation + BRAF G469A (1)
EGFR mutation + BRAF mutation + TP53 mutation (1)
KRAS G12A + BRAF D549N (1)
KRAS G12V + BRAF V600E (1)
MAP2K1 V211D + BRAF mutation (1)
NRAS G12C + BRAF V600E + BRAF V600D (1)
NRAS G13D + BRAF V600E (1)
RAS wild-type + BRAF wild-type + MAP2K1 N57K (1)
ROS1 rearrangement + BRAF V600E (1)
TERT promoter mutation + BRAF V600 (1)
MYD88 L265P + CXCR4 mutation (1)
MYD88 mutation + CD79B mutation (1)
MYD88 wild-type (1)
BRAF K601 (0)
BRAF L597 (0)
BRAF V600E + TERT mutation (0)
BRAF V600E + KRAS G12D (0)
BRAF V600E + MAP2K1 P124S (0)
BRAF exon 11 mutation (0)
BRAF exon 15 mutation (0)
CDKN2A mutation + BRAF V600E (0)
IDH mutation + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)
BTK C481S + MYD88 mutation (0)
BRAF V600E (255)
BRAF mutation (129)
BRAF V600 (106)
BRAF V600K (25)
BRAF wild-type (25)
MYD88 mutation (19)
MYD88 L265P (13)
BRAF G469V (7)
BRAF K601E (7)
RAS wild-type + BRAF wild-type (7)
BRAF D594G (6)
BRAF V600E + RNF43 mutation (6)
EGFR mutation + BRAF V600E (6)
BRAF G466V (4)
BRAF V600E + PIK3CA mutation (4)
BRAF V600G (4)
NRAS mutation + BRAF mutation (4)
BRAF D549G (3)
BRAF G469A (3)
BRAF G469E (3)
BRAF L597Q (3)
BRAF L597R (3)
BRAF T1799A (3)
BRAF V595E (3)
BRAF V600E + TERT mutation (3)
BRAF V600R (3)
BRAF delNVTAP (3)
NRAS Q61K + BRAF V600E (3)
TERT mutation + BRAF V600E (3)
BRAF G466A (2)
BRAF L485W (2)
BRAF V600D (2)
BRAF V600E + MAP2K1 I111S (2)
BRAF V600M (2)
BRAF mutation + MEK1 P124L (2)
BRAF mutation + NF1 mutation (2)
BRAF rearrangement (2)
EGFR mutation + BRAF V600 (2)
IDH1 wild-type + BRAF mutation (2)
KRAS G13D + BRAF mutation (2)
NRAS G12C + BRAF mutation (2)
MYD88 L265P + CD79B mutation (2)
MYD88 mutation + CXCR4 mutation (2)
AKT1 E17K + BRAF V600 (1)
BRAF 486_490 del (1)
BRAF D594N (1)
BRAF G464 (1)
BRAF G464E (1)
BRAF G466E + NF1 Y2285fs*5 + NF1 Y2640fs*3 + TP53 D281Y (1)
BRAF G466V + KIT K509Q (1)
BRAF G469R (1)
BRAF G469S (1)
BRAF G596V (1)
BRAF L505H (1)
BRAF L597K (1)
BRAF L597S (1)
BRAF N486-P490del + TP53 V157G (1)
BRAF S365L (1)
BRAF T599 (1)
BRAF V600 wild-type (1)
BRAF V600DK601del (1)
BRAF V600E + BRAF G469A + BRAF G469V (1)
BRAF V600E + BRAF K601_W604del (1)
BRAF V600E + BRAF L514V (1)
BRAF V600E + BRAF V600K (1)
BRAF V600E + KRAS G12R (1)
BRAF V600E + MSI-H/dMMR (1)
BRAF V600E + TERT E441del + RET N579K + EZH2 D154E + CDK4 S259L (1)
BRAF V600_K601delinsE (1)
BRAF Y472C (1)
BRAF mutation + EGFR mutation (1)
BRAF mutation + MAP2K1 mutation (1)
BRAF mutation + RAS mutation (1)
BRAF mutation + TERT −124C>T (1)
BRAF mutation + TERT −138CC>TT (1)
BRAF mutation + TERT −139CC>TT (1)
BRAF mutation + TERT −146C>T (1)
BRAF mutation + TET2 mutation (1)
BRAF mutation + TP53 mutation (1)
BRAF wild-type + NRAS wild-type (1)
EGFR T790M + BRAF V600E (1)
EGFR exon 19 deletion + BRAF V600E (1)
EGFR mutation + BRAF G469A (1)
EGFR mutation + BRAF mutation + TP53 mutation (1)
KRAS G12A + BRAF D549N (1)
KRAS G12V + BRAF V600E (1)
MAP2K1 V211D + BRAF mutation (1)
NRAS G12C + BRAF V600E + BRAF V600D (1)
NRAS G13D + BRAF V600E (1)
RAS wild-type + BRAF wild-type + MAP2K1 N57K (1)
ROS1 rearrangement + BRAF V600E (1)
TERT promoter mutation + BRAF V600 (1)
MYD88 L265P + CXCR4 mutation (1)
MYD88 mutation + CD79B mutation (1)
MYD88 wild-type (1)
BRAF K601 (0)
BRAF L597 (0)
BRAF V600E + TERT mutation (0)
BRAF V600E + KRAS G12D (0)
BRAF V600E + MAP2K1 P124S (0)
BRAF exon 11 mutation (0)
BRAF exon 15 mutation (0)
CDKN2A mutation + BRAF V600E (0)
IDH mutation + BRAF V600E (0)
IDH mutation + Chr del(1p) + Chr del(19q) + BRAF V600E (0)
BTK C481S + MYD88 mutation (0)
›
Associations
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MYD88 L265P + BRAF V600E
Hairy Cell Leukemia
MYD88 L265P + BRAF V600E
Hairy Cell Leukemia
rituximab
Sensitive: C4 – Case Studies
rituximab
Sensitive
:
C4
rituximab
Sensitive: C4 – Case Studies
rituximab
Sensitive
:
C4
MYD88 L265P + BRAF V600E
Non-Hodgkin’s Lymphoma
MYD88 L265P + BRAF V600E
Non-Hodgkin’s Lymphoma
rituximab
Sensitive: C4 – Case Studies
rituximab
Sensitive
:
C4
rituximab
Sensitive: C4 – Case Studies
rituximab
Sensitive
:
C4
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