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BIOMARKER:
EGFR T790M
i
Other names:
EGFR, ERBB, ERBB1, Epidermal growth factor receptor
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Entrez ID:
1956
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
EGFR exon 19 deletion + EGFR T790M (10)
EGFR mutation + PD-L1 overexpression (8)
MET amplification + EGFR mutation (8)
EGFR exon 19 deletion + PD-L1 overexpression (5)
EGFR mutation + MET amplification (5)
EGFR mutation + PD-L1 expression (5)
EGFR exon 19 deletion + EGFR L643V (4)
EGFR exon 19 deletion + EGFR T790M + EGFR C797S + CTNNB1 exon 3 mutation (4)
PD-L1 expression + EGFR mutation (4)
TA-MUC1 elevation + EGFR expression (4)
TNFRSF10A overexpression + EGFR mutation (4)
EGFR exon 19 deletion + EGFR G724S (3)
EGFR exon 19 deletion + NRAS Q61K (3)
EGFR exon 19 deletion + PTEN K237Cfs*17 (3)
EGFR mutation + ANKRD1 overexpression (3)
EGFR mutation + EGFR amplification (3)
EGFR mutation + MET overexpression (3)
EGFR wild-type + ALK wild-type + PD-L1 expression (3)
MET overexpression + EGFR mutation (3)
AXL expression + EGFR mutation (2)
EGFR C797S + EGFR T790M + EGFR exon 19 deletion + TMB-L (2)
EGFR L858R + EGFR exon 19 deletion (2)
EGFR L858R + PD-L1 overexpression (2)
EGFR L858R + VOPP1-EGFR fusion + EGFR T790M (2)
EGFR exon 19 deletion + MET amplification (2)
EGFR exon 19 deletion + EGFR K754E (2)
EGFR exon 19 deletion + EGFR L861Q + EGFR G873E (2)
EGFR exon 19 deletion + KRAS mutation (2)
EGFR exon 19 deletion + PD-L1 expression (2)
EGFR exon 19 deletion + TP53 mutation + RB1 mutation (2)
EGFR exon 20 insertion + EGFR amplification (2)
EGFR mutation + BCL2L11 deletion (2)
EGFR mutation + CDCA3 underexpression (2)
EGFR mutation + PTEN deletion (2)
EGFR mutation + RET fusion (2)
EGFR mutation + YAP1 overexpression (2)
EGFR mutation + YES1 overexpression (2)
EGFR-SEPTIN14 fusion + EGFR amplification (2)
EGFR exon 19 deletion + MET Amplification + MET D1228V (2)
EML4-ALK gene fusion + EGFR exon 19 deletion + EGFR T790M + EGFR C797G (2)
ERBB3 mutation + TMB-H (2)
HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K (2)
PD-L1 overexpression + EGFR mutation (2)
TMB-H + EGFR exon 19 deletion (2)
TMB-H + EGFR mutation (2)
ALK fusion + EGFR exon 19 deletion + BRAF G466V + MAP2K1 F129L (1)
APC V2194fs + EGFR amplification + EGFR-SEPTIN14 fusion (1)
APOA1 elevation + EGFR T790M (1)
ARID1A underexpression + EGFR mutation (1)
ATM expression + ATM T2333fs* + EGFR negative (1)
AXL overexpression + EGFR mutation (1)
AXL underexpression + EGFR mutation (1)
BCL2L11 deletion + EGFR T790M (1)
BRAF V600E + EGFR expression (1)
CCDC6-RET fusion + EGFR mutation (1)
CD276 underexpression + EGFR mutation (1)
CD74-NRG1 fusion + EGFR mutation + HER-2 mutation (1)
CRKL overexpression + EGFR mutation (1)
EGFR C797S + KRAS amplification + RB1 deletion (1)
EGFR C797S + MET amplification (1)
EGFR E746_A750del + KRAS amplification (1)
EGFR G719A + EGFR S768I + PD-L1 overexpression (1)
EGFR G719A + PD-L1 overexpression (1)
EGFR G719D + EGFR L861Q + CUX1-MET fusion (1)
EGFR L747P + PD-L1 overexpression (1)
EGFR L747_A750delinsP + MET D1228H + MET D1228N + MET D1228Y + MET Y1230H + MET amplification (1)
EGFR L858R + HER-2 amplification + PIK3CA overexpression (1)
EGFR L858R + KDR overexpression + VEGFC overexpression (1)
EGFR L858R + KRAS amplification + RB1 deletion (1)
EGFR L858R + MET amplification (1)
EGFR L858R + MET overexpression (1)
EGFR L858R + MET positive (1)
EGFR L858R + PD-L1 expression (1)
EGFR L858R + PD-L1 underexpression (1)
EGFR L858R + ROS1 fusion (1)
EGFR L858R + ROS1-ADGRG6 fusion (1)
EGFR L858R + TMB-H (1)
EGFR L858R + VEGFA-L (1)
EGFR P719A + PD-L1 overexpression (1)
EGFR T263P + EGFR L858R + MET amplification (1)
EGFR T790M + HER-2 amplification (1)
EGFR T790M + KRAS amplification + RB1 deletion (1)
EGFR T790M + MET amplification (1)
EGFR T790M + MET positive (1)
EGFR T790M + MYC amplification (1)
EGFR T790M + STRN-ALK fusion + EGFR amplification + MET amplification (1)
EGFR T790M + TMB-H (1)
EGFR V843I + KRAS G13D + AKT1 E17K + PD-L1 overexpression (1)
EGFR exon 19 deletion + ALK amplification (1)
EGFR exon 19 deletion + BRAF G464A (1)
EGFR exon 19 deletion + CCND1 overexpression (1)
EGFR exon 19 deletion + EGFR L747S (1)
EGFR exon 19 deletion + EGFR S768I (1)
EGFR exon 19 deletion + EGFR T790M + EGFR C797S + HER-2 amplification (1)
EGFR exon 19 deletion + EGFR T790M + PD-L1 expression (1)
EGFR exon 19 deletion + EGFR exon 21 mutation + TP53 mutation (1)
EGFR exon 19 deletion + LMNA-NTRK1 fusion + EGFR T790M (1)
EGFR exon 19 deletion + MET positive (1)
EGFR exon 19 deletion + MET amplification (1)
EGFR exon 19 deletion + MET amplification + MET D1228H + MET D1228N + MET D1228Y (1)
EGFR exon 19 deletion + MET amplification + MET D1228H + MET D1228N + MET D1228Y + MET Y1230C (1)
EGFR exon 19 deletion + PD-L1 underexpression (1)
EGFR exon 19 deletion + PTEN deletion + PIK3CA overexpression (1)
EGFR exon 19 deletion + RBM10 S167* (1)
EGFR exon 19 deletion + STRN-ALK fusion (1)
EGFR exon 19 deletion + TP53 mutation + CDK6 amplification + KRAS amplification (1)
EGFR exon 19 deletion + TP53 mutation + MET amplification (1)
EGFR exon 19 deletion + VEGFA-L (1)
EGFR exon 20 insertion + PD-L1 overexpression (1)
EGFR exon 20 insertion + TP53 mutation (1)
EGFR expression + KRAS G12C (1)
EGFR expression + TP53 mutation (1)
EGFR fusion + PD-L1 overexpression (1)
EGFR mutation + ALK negative + TMB-H (1)
EGFR mutation + BCL2L11 overexpression (1)
EGFR mutation + BRCA1 overexpression (1)
EGFR mutation + BRCA1 underexpression (1)
EGFR mutation + CCND1 expression + CDKN2A deletion (1)
EGFR mutation + CD73 overexpression (1)
EGFR mutation + Chr 14q31.1-q31.3 (1)
EGFR mutation + Chr 1p13.3-p13.1 (1)
EGFR mutation + EGFR amplification + MET amplification + MTAP deletion (1)
EGFR mutation + ER positive (1)
EGFR mutation + LANCL2 overexpression (1)
EGFR mutation + LINC00460 overexpression (1)
EGFR mutation + MET amplification + EGFR amplification (1)
EGFR mutation + MET amplification + TP53 mutation (1)
EGFR mutation + MET overexpression + MET amplification (1)
EGFR mutation + MET-CEP7 fusion (1)
EGFR mutation + PD-L1 elevation (1)
EGFR mutation + PD-L1 expression + TP53 mutation (1)
EGFR mutation + PD-L1 negative (1)
EGFR mutation + RBBP8 underexpression (1)
EGFR mutation + ROMO1 overexpression (1)
EGFR mutation + RPS6KB1 amplification (1)
EGFR mutation + S100A9 overexpression (1)
EGFR mutation + SYK overexpression (1)
EGFR mutation + TP53 expression (1)
EGFR mutation + TSLP underexpression (1)
EGFR mutation + TTF1 negative (1)
EGFR mutation + WNT5A expression (1)
EGFR negative + ALK negative + PD-L1 expression (1)
EGFR negative + S100A8 elevation (1)
EGFR negative + S100A9 elevation (1)
EGFR negative + SAA1 elevation (1)
EGFR negative + SAA2 elevation (1)
EGFR overexpression + BRAF V600E (1)
EGFR overexpression + BRAF mutation (1)
EGFR overexpression + KRAS 13D (1)
EGFR overexpression + KRAS mutation (1)
EGFR wild-type + ALK wild-type + NT5E overexpression + PD-L1 expression (1)
EGFR wild-type + Chr 11p11.11-q12.1 (1)
EGFR wild-type + Chr 7q31.1-q31.31 (1)
EGFR wild-type + Chr 9q21.31-q22.2 (1)
EGFR wild-type + MET amplification (1)
EGFR wild-type + MET overexpression (1)
EGFR-SEC61G fusion + EGFR amplification (1)
EGFRvIII mutation + EGFR-SEPTIN14 fusion + EGFR amplification (1)
EPHA2 expression + EGFR mutation (1)
ERCC2 positive + SYP negative + EGFR exon 21 mutation (1)
GPRC6A-RET fusion + EGFR mutation (1)
HER-2 amplification + EGFR mutation (1)
HR negative + EGFR amplification (1)
KIF5B-RET fusion + EGFR exon 19 deletion (1)
KRAS mutation + EGFR amplification (1)
MET exon 14 mutation + EGFR wild-type (1)
MET negative + EGFR mutation (1)
MET overexpression + EGFR wild-type (1)
MET positive + EGFR mutation (1)
NOTCH2-NTRK1 fusion + EGFR L858R (1)
PD-L1 underexpression + EGFR mutation (1)
PTGS2 positive + MET positive + PBK positive + EGFR mutation (1)
RBM10 deletion + EGFR mutation (1)
RBM10 underexpression + EGFR mutation (1)
ROS1 translocation + EGFR wild-type (1)
SHTN1-RET fusion + EGFR mutation (1)
SPECC1-RET fusion + EGFR mutation (1)
STRN-ALK fusion + EML4-ALK fusion + EGFR T790M (1)
TERT mutation + EGFR T790M + EGFR exon 20 insertion (1)
TLN1-RET fusion + EGFR mutation (1)
TRIM24-RET fusion + EGFR mutation (1)
TRIM33-RET fusion + EGFR mutation (1)
CALR elevation + EGFR mutation (0)
HER-2 positive + FGFR1 amplification (0)
PD-L1 underexpression + EGFR wild-type (0)
EGFR exon 19 deletion + EGFR T790M (10)
EGFR mutation + PD-L1 overexpression (8)
MET amplification + EGFR mutation (8)
EGFR exon 19 deletion + PD-L1 overexpression (5)
EGFR mutation + MET amplification (5)
EGFR mutation + PD-L1 expression (5)
EGFR exon 19 deletion + EGFR L643V (4)
EGFR exon 19 deletion + EGFR T790M + EGFR C797S + CTNNB1 exon 3 mutation (4)
PD-L1 expression + EGFR mutation (4)
TA-MUC1 elevation + EGFR expression (4)
TNFRSF10A overexpression + EGFR mutation (4)
EGFR exon 19 deletion + EGFR G724S (3)
EGFR exon 19 deletion + NRAS Q61K (3)
EGFR exon 19 deletion + PTEN K237Cfs*17 (3)
EGFR mutation + ANKRD1 overexpression (3)
EGFR mutation + EGFR amplification (3)
EGFR mutation + MET overexpression (3)
EGFR wild-type + ALK wild-type + PD-L1 expression (3)
MET overexpression + EGFR mutation (3)
AXL expression + EGFR mutation (2)
EGFR C797S + EGFR T790M + EGFR exon 19 deletion + TMB-L (2)
EGFR L858R + EGFR exon 19 deletion (2)
EGFR L858R + PD-L1 overexpression (2)
EGFR L858R + VOPP1-EGFR fusion + EGFR T790M (2)
EGFR exon 19 deletion + MET amplification (2)
EGFR exon 19 deletion + EGFR K754E (2)
EGFR exon 19 deletion + EGFR L861Q + EGFR G873E (2)
EGFR exon 19 deletion + KRAS mutation (2)
EGFR exon 19 deletion + PD-L1 expression (2)
EGFR exon 19 deletion + TP53 mutation + RB1 mutation (2)
EGFR exon 20 insertion + EGFR amplification (2)
EGFR mutation + BCL2L11 deletion (2)
EGFR mutation + CDCA3 underexpression (2)
EGFR mutation + PTEN deletion (2)
EGFR mutation + RET fusion (2)
EGFR mutation + YAP1 overexpression (2)
EGFR mutation + YES1 overexpression (2)
EGFR-SEPTIN14 fusion + EGFR amplification (2)
EGFR exon 19 deletion + MET Amplification + MET D1228V (2)
EML4-ALK gene fusion + EGFR exon 19 deletion + EGFR T790M + EGFR C797G (2)
ERBB3 mutation + TMB-H (2)
HER-2 amplification + EGFR-ZNF880 fusion + EGFR E114K (2)
PD-L1 overexpression + EGFR mutation (2)
TMB-H + EGFR exon 19 deletion (2)
TMB-H + EGFR mutation (2)
ALK fusion + EGFR exon 19 deletion + BRAF G466V + MAP2K1 F129L (1)
APC V2194fs + EGFR amplification + EGFR-SEPTIN14 fusion (1)
APOA1 elevation + EGFR T790M (1)
ARID1A underexpression + EGFR mutation (1)
ATM expression + ATM T2333fs* + EGFR negative (1)
AXL overexpression + EGFR mutation (1)
AXL underexpression + EGFR mutation (1)
BCL2L11 deletion + EGFR T790M (1)
BRAF V600E + EGFR expression (1)
CCDC6-RET fusion + EGFR mutation (1)
CD276 underexpression + EGFR mutation (1)
CD74-NRG1 fusion + EGFR mutation + HER-2 mutation (1)
CRKL overexpression + EGFR mutation (1)
EGFR C797S + KRAS amplification + RB1 deletion (1)
EGFR C797S + MET amplification (1)
EGFR E746_A750del + KRAS amplification (1)
EGFR G719A + EGFR S768I + PD-L1 overexpression (1)
EGFR G719A + PD-L1 overexpression (1)
EGFR G719D + EGFR L861Q + CUX1-MET fusion (1)
EGFR L747P + PD-L1 overexpression (1)
EGFR L747_A750delinsP + MET D1228H + MET D1228N + MET D1228Y + MET Y1230H + MET amplification (1)
EGFR L858R + HER-2 amplification + PIK3CA overexpression (1)
EGFR L858R + KDR overexpression + VEGFC overexpression (1)
EGFR L858R + KRAS amplification + RB1 deletion (1)
EGFR L858R + MET amplification (1)
EGFR L858R + MET overexpression (1)
EGFR L858R + MET positive (1)
EGFR L858R + PD-L1 expression (1)
EGFR L858R + PD-L1 underexpression (1)
EGFR L858R + ROS1 fusion (1)
EGFR L858R + ROS1-ADGRG6 fusion (1)
EGFR L858R + TMB-H (1)
EGFR L858R + VEGFA-L (1)
EGFR P719A + PD-L1 overexpression (1)
EGFR T263P + EGFR L858R + MET amplification (1)
EGFR T790M + HER-2 amplification (1)
EGFR T790M + KRAS amplification + RB1 deletion (1)
EGFR T790M + MET amplification (1)
EGFR T790M + MET positive (1)
EGFR T790M + MYC amplification (1)
EGFR T790M + STRN-ALK fusion + EGFR amplification + MET amplification (1)
EGFR T790M + TMB-H (1)
EGFR V843I + KRAS G13D + AKT1 E17K + PD-L1 overexpression (1)
EGFR exon 19 deletion + ALK amplification (1)
EGFR exon 19 deletion + BRAF G464A (1)
EGFR exon 19 deletion + CCND1 overexpression (1)
EGFR exon 19 deletion + EGFR L747S (1)
EGFR exon 19 deletion + EGFR S768I (1)
EGFR exon 19 deletion + EGFR T790M + EGFR C797S + HER-2 amplification (1)
EGFR exon 19 deletion + EGFR T790M + PD-L1 expression (1)
EGFR exon 19 deletion + EGFR exon 21 mutation + TP53 mutation (1)
EGFR exon 19 deletion + LMNA-NTRK1 fusion + EGFR T790M (1)
EGFR exon 19 deletion + MET positive (1)
EGFR exon 19 deletion + MET amplification (1)
EGFR exon 19 deletion + MET amplification + MET D1228H + MET D1228N + MET D1228Y (1)
EGFR exon 19 deletion + MET amplification + MET D1228H + MET D1228N + MET D1228Y + MET Y1230C (1)
EGFR exon 19 deletion + PD-L1 underexpression (1)
EGFR exon 19 deletion + PTEN deletion + PIK3CA overexpression (1)
EGFR exon 19 deletion + RBM10 S167* (1)
EGFR exon 19 deletion + STRN-ALK fusion (1)
EGFR exon 19 deletion + TP53 mutation + CDK6 amplification + KRAS amplification (1)
EGFR exon 19 deletion + TP53 mutation + MET amplification (1)
EGFR exon 19 deletion + VEGFA-L (1)
EGFR exon 20 insertion + PD-L1 overexpression (1)
EGFR exon 20 insertion + TP53 mutation (1)
EGFR expression + KRAS G12C (1)
EGFR expression + TP53 mutation (1)
EGFR fusion + PD-L1 overexpression (1)
EGFR mutation + ALK negative + TMB-H (1)
EGFR mutation + BCL2L11 overexpression (1)
EGFR mutation + BRCA1 overexpression (1)
EGFR mutation + BRCA1 underexpression (1)
EGFR mutation + CCND1 expression + CDKN2A deletion (1)
EGFR mutation + CD73 overexpression (1)
EGFR mutation + Chr 14q31.1-q31.3 (1)
EGFR mutation + Chr 1p13.3-p13.1 (1)
EGFR mutation + EGFR amplification + MET amplification + MTAP deletion (1)
EGFR mutation + ER positive (1)
EGFR mutation + LANCL2 overexpression (1)
EGFR mutation + LINC00460 overexpression (1)
EGFR mutation + MET amplification + EGFR amplification (1)
EGFR mutation + MET amplification + TP53 mutation (1)
EGFR mutation + MET overexpression + MET amplification (1)
EGFR mutation + MET-CEP7 fusion (1)
EGFR mutation + PD-L1 elevation (1)
EGFR mutation + PD-L1 expression + TP53 mutation (1)
EGFR mutation + PD-L1 negative (1)
EGFR mutation + RBBP8 underexpression (1)
EGFR mutation + ROMO1 overexpression (1)
EGFR mutation + RPS6KB1 amplification (1)
EGFR mutation + S100A9 overexpression (1)
EGFR mutation + SYK overexpression (1)
EGFR mutation + TP53 expression (1)
EGFR mutation + TSLP underexpression (1)
EGFR mutation + TTF1 negative (1)
EGFR mutation + WNT5A expression (1)
EGFR negative + ALK negative + PD-L1 expression (1)
EGFR negative + S100A8 elevation (1)
EGFR negative + S100A9 elevation (1)
EGFR negative + SAA1 elevation (1)
EGFR negative + SAA2 elevation (1)
EGFR overexpression + BRAF V600E (1)
EGFR overexpression + BRAF mutation (1)
EGFR overexpression + KRAS 13D (1)
EGFR overexpression + KRAS mutation (1)
EGFR wild-type + ALK wild-type + NT5E overexpression + PD-L1 expression (1)
EGFR wild-type + Chr 11p11.11-q12.1 (1)
EGFR wild-type + Chr 7q31.1-q31.31 (1)
EGFR wild-type + Chr 9q21.31-q22.2 (1)
EGFR wild-type + MET amplification (1)
EGFR wild-type + MET overexpression (1)
EGFR-SEC61G fusion + EGFR amplification (1)
EGFRvIII mutation + EGFR-SEPTIN14 fusion + EGFR amplification (1)
EPHA2 expression + EGFR mutation (1)
ERCC2 positive + SYP negative + EGFR exon 21 mutation (1)
GPRC6A-RET fusion + EGFR mutation (1)
HER-2 amplification + EGFR mutation (1)
HR negative + EGFR amplification (1)
KIF5B-RET fusion + EGFR exon 19 deletion (1)
KRAS mutation + EGFR amplification (1)
MET exon 14 mutation + EGFR wild-type (1)
MET negative + EGFR mutation (1)
MET overexpression + EGFR wild-type (1)
MET positive + EGFR mutation (1)
NOTCH2-NTRK1 fusion + EGFR L858R (1)
PD-L1 underexpression + EGFR mutation (1)
PTGS2 positive + MET positive + PBK positive + EGFR mutation (1)
RBM10 deletion + EGFR mutation (1)
RBM10 underexpression + EGFR mutation (1)
ROS1 translocation + EGFR wild-type (1)
SHTN1-RET fusion + EGFR mutation (1)
SPECC1-RET fusion + EGFR mutation (1)
STRN-ALK fusion + EML4-ALK fusion + EGFR T790M (1)
TERT mutation + EGFR T790M + EGFR exon 20 insertion (1)
TLN1-RET fusion + EGFR mutation (1)
TRIM24-RET fusion + EGFR mutation (1)
TRIM33-RET fusion + EGFR mutation (1)
CALR elevation + EGFR mutation (0)
HER-2 positive + FGFR1 amplification (0)
PD-L1 underexpression + EGFR wild-type (0)
›
Related tests:
FoundationOne® CDx (110)
Guardant360® CDx (54)
cobas® EGFR Mutation Test v2 (13)
Target Selector™ EGFR Mutation Assay
therascreen® EGFR Plus RGQ PCR Kit
FoundationOne® CDx (110)
Guardant360® CDx (54)
cobas® EGFR Mutation Test v2 (13)
Target Selector™ EGFR Mutation Assay
therascreen® EGFR Plus RGQ PCR Kit
Associations
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Reset Filters
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
osimertinib
Sensitive: A1 - Approval
osimertinib
Sensitive
:
A1
osimertinib
Sensitive: A1 - Approval
osimertinib
Sensitive
:
A1
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
lazertinib
Sensitive: A1 - Approval
lazertinib
Sensitive
:
A1
lazertinib
Sensitive: A1 - Approval
lazertinib
Sensitive
:
A1
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
aumolertinib
Sensitive: A1 - Approval
aumolertinib
Sensitive
:
A1
aumolertinib
Sensitive: A1 - Approval
aumolertinib
Sensitive
:
A1
EGFR T790M
Lung Non-Squamous Non-Small Cell Cancer
EGFR T790M
Lung Non-Squamous Non-Small Cell Cancer
osimertinib
Sensitive: A2 - Guideline
osimertinib
Sensitive
:
A2
osimertinib
Sensitive: A2 - Guideline
osimertinib
Sensitive
:
A2
EGFR T790M
Lung Adenocarcinoma
EGFR T790M
Lung Adenocarcinoma
erlotinib
Sensitive: B - Late Trials
erlotinib
Sensitive
:
B
erlotinib
Sensitive: B - Late Trials
erlotinib
Sensitive
:
B
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
afatinib
Sensitive: B - Late Trials
afatinib
Sensitive
:
B
afatinib
Sensitive: B - Late Trials
afatinib
Sensitive
:
B
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
erlotinib + ramucirumab
Sensitive: B - Late Trials
erlotinib + ramucirumab
Sensitive
:
B
erlotinib + ramucirumab
Sensitive: B - Late Trials
erlotinib + ramucirumab
Sensitive
:
B
EGFR T790M
Lung Adenocarcinoma
EGFR T790M
Lung Adenocarcinoma
gefitinib
Sensitive: B - Late Trials
gefitinib
Sensitive
:
B
gefitinib
Sensitive: B - Late Trials
gefitinib
Sensitive
:
B
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
bevacizumab
Sensitive: B - Late Trials
bevacizumab
Sensitive
:
B
bevacizumab
Sensitive: B - Late Trials
bevacizumab
Sensitive
:
B
EGFR T790M
Lung Adenocarcinoma
EGFR T790M
Lung Adenocarcinoma
osimertinib
Resistant: C1 - Off-label
osimertinib
Resistant
:
C1
osimertinib
Resistant: C1 - Off-label
osimertinib
Resistant
:
C1
EGFR T790M
Lung Cancer
EGFR T790M
Lung Cancer
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
EGFR T790M
Small Cell Lung Cancer
EGFR T790M
Small Cell Lung Cancer
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
osimertinib
Sensitive: C1 - Off-label
osimertinib
Sensitive
:
C1
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
bevacizumab + osimertinib
Sensitive: C2 – Inclusion Criteria
bevacizumab + osimertinib
Sensitive
:
C2
bevacizumab + osimertinib
Sensitive: C2 – Inclusion Criteria
bevacizumab + osimertinib
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
rociletinib
Sensitive: C2 – Inclusion Criteria
rociletinib
Sensitive
:
C2
rociletinib
Sensitive: C2 – Inclusion Criteria
rociletinib
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
ASP8273
Sensitive: C2 – Inclusion Criteria
ASP8273
Sensitive
:
C2
ASP8273
Sensitive: C2 – Inclusion Criteria
ASP8273
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
ASK120067
Sensitive: C2 – Inclusion Criteria
ASK120067
Sensitive
:
C2
ASK120067
Sensitive: C2 – Inclusion Criteria
ASK120067
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
osimertinib + ramucirumab
Sensitive: C2 – Inclusion Criteria
osimertinib + ramucirumab
Sensitive
:
C2
osimertinib + ramucirumab
Sensitive: C2 – Inclusion Criteria
osimertinib + ramucirumab
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
olmutinib
Sensitive: C2 – Inclusion Criteria
olmutinib
Sensitive
:
C2
olmutinib
Sensitive: C2 – Inclusion Criteria
olmutinib
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
osimertinib + ABT 263
Sensitive: C2 – Inclusion Criteria
osimertinib + ABT 263
Sensitive
:
C2
osimertinib + ABT 263
Sensitive: C2 – Inclusion Criteria
osimertinib + ABT 263
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
amivantamab-vmjw
Sensitive: C2 – Inclusion Criteria
amivantamab-vmjw
Sensitive
:
C2
amivantamab-vmjw
Sensitive: C2 – Inclusion Criteria
amivantamab-vmjw
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
anlotinib
Sensitive: C2 – Inclusion Criteria
anlotinib
Sensitive
:
C2
anlotinib
Sensitive: C2 – Inclusion Criteria
anlotinib
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
firmonertinib
Sensitive: C2 – Inclusion Criteria
firmonertinib
Sensitive
:
C2
firmonertinib
Sensitive: C2 – Inclusion Criteria
firmonertinib
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
abivertinib
Sensitive: C2 – Inclusion Criteria
abivertinib
Sensitive
:
C2
abivertinib
Sensitive: C2 – Inclusion Criteria
abivertinib
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
befotertinib
Sensitive: C2 – Inclusion Criteria
befotertinib
Sensitive
:
C2
befotertinib
Sensitive: C2 – Inclusion Criteria
befotertinib
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
rilertinib
Sensitive: C2 – Inclusion Criteria
rilertinib
Sensitive
:
C2
rilertinib
Sensitive: C2 – Inclusion Criteria
rilertinib
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
osimertinib + anlotinib
Sensitive: C2 – Inclusion Criteria
osimertinib + anlotinib
Sensitive
:
C2
osimertinib + anlotinib
Sensitive: C2 – Inclusion Criteria
osimertinib + anlotinib
Sensitive
:
C2
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
AUY922
Sensitive: C2 – Inclusion Criteria
AUY922
Sensitive
:
C2
AUY922
Sensitive: C2 – Inclusion Criteria
AUY922
Sensitive
:
C2
EGFR T790M
Lung Non-Squamous Non-Small Cell Cancer
EGFR T790M
Lung Non-Squamous Non-Small Cell Cancer
PD-L1 inhibitor
Resistant: C3 – Early Trials
PD-L1 inhibitor
Resistant
:
C3
PD-L1 inhibitor
Resistant: C3 – Early Trials
PD-L1 inhibitor
Resistant
:
C3
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
EGFR inhibitor
Resistant: C3 – Early Trials
EGFR inhibitor
Resistant
:
C3
EGFR inhibitor
Resistant: C3 – Early Trials
EGFR inhibitor
Resistant
:
C3
EGFR T790M
Lung Adenocarcinoma
EGFR T790M
Lung Adenocarcinoma
bevacizumab + osimertinib
Resistant: C3 – Early Trials
bevacizumab + osimertinib
Resistant
:
C3
bevacizumab + osimertinib
Resistant: C3 – Early Trials
bevacizumab + osimertinib
Resistant
:
C3
EGFR T790M
Non Small Cell Lung Cancer
EGFR T790M
Non Small Cell Lung Cancer
Tyrosine kinase inhibitor
Resistant: C3 – Early Trials
Tyrosine kinase inhibitor
Resistant
:
C3
Tyrosine kinase inhibitor
Resistant: C3 – Early Trials
Tyrosine kinase inhibitor
Resistant
:
C3
EGFR T790M
Lung Adenocarcinoma
EGFR T790M
Lung Adenocarcinoma
Tyrosine kinase inhibitor
Sensitive: C3 – Early Trials
Tyrosine kinase inhibitor
Sensitive
:
C3
Tyrosine kinase inhibitor
Sensitive: C3 – Early Trials
Tyrosine kinase inhibitor
Sensitive
:
C3
^
^
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