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BIOMARKER:

EGFR exon 19 deletion + PD-L1 overexpression

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Other names: EGFR, ERBB, ERBB1, Epidermal growth factor receptor, PD-L1, CD274, HPD-L1, PD-L1, B7H1, PDL1, Programmed death ligand 1, B7-H1, B7-H, PDCD1L1, PDCD1LG1, PDCD1 Ligand 1, B7 homolog 1, CD274 Antigen, Programmed cell death 1 ligand 1, CD274 molecule
Entrez ID:
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Trials
EGFR exon 19 deletion + PD-L1 overexpression
LUAD
Tyrosine kinase inhibitor
Resistant: C3 – Early Trials
EGFR exon 19 deletion + PD-L1 overexpression
LUAD
afatinib + atezolizumab
Sensitive: C4 – Case Studies
EGFR exon 19 deletion + PD-L1 overexpression
LUAD
gefitinib
Resistant: C4 – Case Studies