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BIOMARKER:

TNFRSF10A overexpression + EGFR mutation

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Other names: EGFR, ERBB, ERBB1, Epidermal growth factor receptor, TNF Receptor Superfamily Member 10a, TRAILR1, DR4, Tumor Necrosis Factor Receptor Superfamily, Member 10a, Tumor Necrosis Factor Receptor Superfamily Member 10A, TNF-Related Apoptosis-Inducing Ligand Receptor 1, TRAIL Receptor 1, Death Receptor 4, TRAILR-1, TRAIL-R1, CD261, APO2, Tumor Necrosis Factor Receptor Superfamily Member 10a Variant 2, Cytotoxic TRAIL Receptor, CD261 Antigen, TNFRSF10A, Apo2
Entrez ID:
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Trials
TNFRSF10A overexpression + EGFR mutation
NSCLC
erlotinib
Resistant: C3 – Early Trials
TNFRSF10A overexpression + EGFR mutation
NSCLC
gefitinib
Resistant: C3 – Early Trials
TNFRSF10A overexpression + EGFR mutation
NSCLC
icotinib
Resistant: C3 – Early Trials
TNFRSF10A overexpression + EGFR mutation
NSCLC
osimertinib
Resistant: D – Preclinical