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BIOMARKER:

EGFR exon 19 deletion + NRAS Q61K

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Other names: NRAS1, N-Ras Protein Part 4, Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog, NRAS, Neuroblastoma RAS Viral Oncogene Homolog, NRAS Proto-Oncogene, EGFR, ERBB, ERBB1, Epidermal growth factor receptor
Entrez ID:
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Trials
EGFR exon 19 deletion + NRAS Q61K
LUAD
gefitinib
Resistant: D – Preclinical
EGFR exon 19 deletion + NRAS Q61K
LUAD
gefitinib + selumetinib
Sensitive: D – Preclinical
EGFR exon 19 deletion + NRAS Q61K
LUAD
gefitinib + CI-1040
Sensitive: D – Preclinical