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DRUG:

PLB1004

i
Other names: PLB1004
Associations
Company:
Avistone Biotech
Drug class:
EGFR inhibitor
Related drugs:
Associations
7d
Trial primary completion date • EGFR exon 20 • Metastases
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation
|
PLB1004
3ms
New P2 trial • Metastases
|
Tagrisso (osimertinib) • bozitinib (APL-101) • PLB1004
4ms
A Study of the Oral EGFR Inhibitor PLB1004 in Non-Small Cell Lung Cancer (clinicaltrials.gov)
P1, N=81, Recruiting, Avistone Biotechnology Co., Ltd. | Active, not recruiting --> Recruiting | Initiation date: Nov 2023 --> Jul 2024
Enrollment open • Trial initiation date
|
EGFR (Epidermal growth factor receptor)
|
PLB1004
8ms
New P1/2 trial
|
bozitinib (APL-101) • PLB1004
9ms
New P3 trial
|
EGFR (Epidermal growth factor receptor)
|
cisplatin • carboplatin • Tyvyt (sintilimab) • pemetrexed • PLB1004
11ms
A Study of the Oral EGFR Inhibitor PLB1004 in Non-Small Cell Lung Cancer (clinicaltrials.gov)
P1, N=82, Active, not recruiting, Avistone Biotechnology Co., Ltd. | Not yet recruiting --> Active, not recruiting
Enrollment closed
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR exon 20 insertion • EGFR exon 20 mutation
|
PLB1004
1year
A Study of the Oral EGFR Inhibitor PLB1004 in Non-Small Cell Lung Cancer (clinicaltrials.gov)
P1, N=82, Not yet recruiting, Avistone Biotechnology Co., Ltd.
New P1 trial
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation • EGFR exon 20 insertion • EGFR exon 20 mutation
|
PLB1004
1year
New P2 trial • EGFR exon 20 • Metastases
|
EGFR (Epidermal growth factor receptor)
|
EGFR mutation
|
PLB1004
1year
Assessing the Safety and Efficacy of PLB1004 in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) (clinicaltrials.gov)
P1, N=91, Active, not recruiting, Avistone Biotechnology Co., Ltd. | Recruiting --> Active, not recruiting | Trial completion date: May 2023 --> Nov 2024 | Trial primary completion date: May 2022 --> Apr 2023
Enrollment closed • Trial completion date • Trial primary completion date • Metastases
|
EGFR (Epidermal growth factor receptor) • HER-2 (Human epidermal growth factor receptor 2)
|
EGFR mutation • HER-2 mutation
|
PLB1004