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DRUG:

IBI-389

i
Other names: IBI-389, IBI389, IBI 389
Associations
Company:
Innovent Biologics
Drug class:
CD3 agonist, CLDN18.2 inhibitor
Related drugs:
Associations
11ms
Safety and Efficacy of IBI389 Single Agent, and in Combination With Sintilimab, in Patients With Advanced Malignancies (clinicaltrials.gov)
P1, N=320, Recruiting, Innovent Biologics (Suzhou) Co. Ltd. | Phase classification: P1a/1b --> P1 | Trial completion date: Apr 2024 --> Sep 2024 | Trial primary completion date: Dec 2023 --> Apr 2024
Phase classification • Trial completion date • Trial primary completion date • Combination therapy • Metastases
|
CLDN18 (Claudin 18)
|
CLDN18.2 expression
|
Tyvyt (sintilimab) • IBI-389
almost1year
New P2 trial • Metastases
|
CLDN18 (Claudin 18)
|
CLDN18.2 positive
|
gemcitabine • albumin-bound paclitaxel • IBI-389
2years
Safety and Efficacy of IBI389 Single Agent, and in Combination With Sintilimab, in Patients With Advanced Malignancies (clinicaltrials.gov)
P1a/1b, N=320, Recruiting, Innovent Biologics (Suzhou) Co. Ltd. | Not yet recruiting --> Recruiting
Enrollment open • Combination therapy • Metastases
|
CLDN18 (Claudin 18)
|
CLDN18.2 expression
|
Tyvyt (sintilimab) • IBI-389
almost3years
Clinical • New P1 trial • Combination therapy
|
CLDN18 (Claudin 18)
|
CLDN18.2 expression
|
Tyvyt (sintilimab) • IBI-389