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DRUG:

givastomig (TJ-CD4B)

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Company:

ABL Bio, I-Mab

Drug class:

CLDN18.2 inhibitor, CD137 agonist

Related drugs:

zolbetuximab-clzb (11)

TAC101-Claudin18.2 (0)

ALG.APV-527 (1)

PF-08046049 (1)

PF-05082566 (1)

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CLDN18.2 expression	Gastroesophageal Cancer	CLDN18.2 expression	Gastroesophageal Cancer	TJ-CD4B Sensitive: C3 – Early Trials TJ-CD4B Sensitive : C3	TJ-CD4B Sensitive: C3 – Early Trials TJ-CD4B Sensitive : C3
CLDN18.2 expression	Solid Tumor	CLDN18.2 expression	Solid Tumor	TJ-CD4B Sensitive: D – Preclinical TJ-CD4B Sensitive : D	TJ-CD4B Sensitive: D – Preclinical TJ-CD4B Sensitive : D
CLDN18.2 expression	Gastric Cancer	CLDN18.2 expression	Gastric Cancer	TJ-CD4B Sensitive: D – Preclinical TJ-CD4B Sensitive : D	TJ-CD4B Sensitive: D – Preclinical TJ-CD4B Sensitive : D
CLDN18.2 expression	Gastric Cancer	CLDN18.2 expression	Gastric Cancer	nivolumab + TJ-CD4B Sensitive: D – Preclinical nivolumab + TJ-CD4B Sensitive : D	nivolumab + TJ-CD4B Sensitive: D – Preclinical nivolumab + TJ-CD4B Sensitive : D