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BIOMARKER:

NRAS amplification

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Entrez ID:

Related biomarkers:

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NRAS mutation (125)

RAS wild-type (17)

NRAS wild-type (10)

NRAS mutation + BRAF mutation (4)

FLT3 mutation + NRAS mutation (3)

NRAS Q61K + BRAF V600E (3)

NRAS exon 2 mutation (3)

NRAS exon 4 mutation (3)

EGFR mutation + NRAS Q61K (2)

NRAS G12C + BRAF mutation (2)

NRAS exon 3 mutation (2)

ARAF mutation + NRAS mutation (1)

ASXL1 mutation + NRAS mutation (1)

BRAF wild-type + NRAS wild-type (1)

DNMT3A mutation + ASXL1 mutation + NRAS mutation (1)

DNMT3A mutation + NRAS mutation (1)

EGFR exon 20 insertion + NRAS G13V + NF1 R69fs + NF1 S340fs (1)

FLT3 mutation + NRAS mutation + PTPN11 mutation (1)

FLT3-ITD mutation + ASXL1 mutation + NRAS mutation (1)

FLT3-ITD mutation + DNMT3A mutation + NRAS mutation (1)

FLT3-ITD mutation + NRAS mutation + GATA2 mutation (1)

FLT3-ITD mutation+ DNMT3A mutation + ASXL1 mutation + NRAS mutation (1)

HRAS Q61L + NRAS Q61K (1)

IDH2 mutation + NRAS mutation (1)

NF1 L581Ffs*6 + KRAS A146P + NRAS Q61K + TP53 R175H + PD-L1 T290M (1)

NPM1 mutation + NRAS mutation (1)

NPM1 mutation + SRSF2 mutation + FLT3-ITD mutation+ DNMT3A mutation + ASXL1 mutation + NRAS mutation (1)

NRAS G115Efs*46 (1)

NRAS G12C + BRAF V600E + BRAF V600D (1)

NRAS G13D + BRAF V600E (1)

NRAS mutation + U2AF1 mutation (1)

SETBP1 mutation + NRAS mutation (1)

SRSF2 mutation + DNMT3A mutation + ASXL1 mutation + NRAS mutation (1)

TET2 mutation + NRAS mutation (1)

NRAS mutation (125)

RAS wild-type (17)

NRAS wild-type (10)

NRAS mutation + BRAF mutation (4)

FLT3 mutation + NRAS mutation (3)

NRAS Q61K + BRAF V600E (3)

NRAS exon 2 mutation (3)

NRAS exon 4 mutation (3)

EGFR mutation + NRAS Q61K (2)

NRAS G12C + BRAF mutation (2)

NRAS exon 3 mutation (2)

ARAF mutation + NRAS mutation (1)

ASXL1 mutation + NRAS mutation (1)

BRAF wild-type + NRAS wild-type (1)

DNMT3A mutation + ASXL1 mutation + NRAS mutation (1)

DNMT3A mutation + NRAS mutation (1)

EGFR exon 20 insertion + NRAS G13V + NF1 R69fs + NF1 S340fs (1)

FLT3 mutation + NRAS mutation + PTPN11 mutation (1)

FLT3-ITD mutation + ASXL1 mutation + NRAS mutation (1)

FLT3-ITD mutation + DNMT3A mutation + NRAS mutation (1)

FLT3-ITD mutation + NRAS mutation + GATA2 mutation (1)

FLT3-ITD mutation+ DNMT3A mutation + ASXL1 mutation + NRAS mutation (1)

HRAS Q61L + NRAS Q61K (1)

IDH2 mutation + NRAS mutation (1)

NF1 L581Ffs*6 + KRAS A146P + NRAS Q61K + TP53 R175H + PD-L1 T290M (1)

NPM1 mutation + NRAS mutation (1)

NPM1 mutation + SRSF2 mutation + FLT3-ITD mutation+ DNMT3A mutation + ASXL1 mutation + NRAS mutation (1)

NRAS G115Efs*46 (1)

NRAS G12C + BRAF V600E + BRAF V600D (1)

NRAS G13D + BRAF V600E (1)

NRAS mutation + U2AF1 mutation (1)

SETBP1 mutation + NRAS mutation (1)

SRSF2 mutation + DNMT3A mutation + ASXL1 mutation + NRAS mutation (1)

TET2 mutation + NRAS mutation (1)

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NRAS amplification	Colorectal Cancer	NRAS amplification	Colorectal Cancer	EGFR inhibitor Resistant: C3 – Early Trials EGFR inhibitor Resistant : C3	EGFR inhibitor Resistant: C3 – Early Trials EGFR inhibitor Resistant : C3
NRAS amplification	Non Small Cell Lung Cancer	NRAS amplification	Non Small Cell Lung Cancer	trametinib + infigratinib Resistant: D – Preclinical trametinib + infigratinib Resistant : D	trametinib + infigratinib Resistant: D – Preclinical trametinib + infigratinib Resistant : D
NRAS amplification	Melanoma	NRAS amplification	Melanoma	binimetinib Sensitive: D – Preclinical binimetinib Sensitive : D	binimetinib Sensitive: D – Preclinical binimetinib Sensitive : D
NRAS amplification	Non Small Cell Lung Cancer	NRAS amplification	Non Small Cell Lung Cancer	infigratinib Resistant: D – Preclinical infigratinib Resistant : D	infigratinib Resistant: D – Preclinical infigratinib Resistant : D