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DRUG:

metformin

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Company:

Generic mfg.

Drug class:

AMPK activator

Related drugs:

‹

metformin hydrochloride (0)

antroquinonol (0)

isoquercetin (0)

metformin hydrochloride (0)

antroquinonol (0)

isoquercetin (0)

›

KRAS mutation	Colorectal Cancer	KRAS mutation	Colorectal Cancer	irinotecan + metformin Sensitive: C3 – Early Trials irinotecan + metformin Sensitive : C3	irinotecan + metformin Sensitive: C3 – Early Trials irinotecan + metformin Sensitive : C3
IDH1 mutation	Cholangiocarcinoma	IDH1 mutation	Cholangiocarcinoma	metformin Sensitive: C3 – Early Trials metformin Sensitive : C3	metformin Sensitive: C3 – Early Trials metformin Sensitive : C3
IDH1 mutation	Sarcoma	IDH1 mutation	Sarcoma	metformin Sensitive: C3 – Early Trials metformin Sensitive : C3	metformin Sensitive: C3 – Early Trials metformin Sensitive : C3
IDH1 mutation	Glioma	IDH1 mutation	Glioma	metformin Sensitive: C3 – Early Trials metformin Sensitive : C3	metformin Sensitive: C3 – Early Trials metformin Sensitive : C3
MGMT promoter methylation	Glioblastoma	MGMT promoter methylation	Glioblastoma	metformin Sensitive: C3 – Early Trials metformin Sensitive : C3	metformin Sensitive: C3 – Early Trials metformin Sensitive : C3
ER positive	Estrogen Receptor Positive Breast Cancer	ER positive	Estrogen Receptor Positive Breast Cancer	metformin Sensitive: D – Preclinical metformin Sensitive : D	metformin Sensitive: D – Preclinical metformin Sensitive : D
HSPA6 expression	Esophageal Squamous Cell Carcinoma	HSPA6 expression	Esophageal Squamous Cell Carcinoma	metformin Sensitive: D – Preclinical metformin Sensitive : D	metformin Sensitive: D – Preclinical metformin Sensitive : D
MCT1 overexpression + SLC16A3 overexpression	Multiple Myeloma	MCT1 overexpression + SLC16A3 overexpression	Multiple Myeloma	metformin + syrosingopine Sensitive: D – Preclinical metformin + syrosingopine Sensitive : D	metformin + syrosingopine Sensitive: D – Preclinical metformin + syrosingopine Sensitive : D
ROS1 amplification	Colon Cancer	ROS1 amplification	Colon Cancer	metformin + efavirenz + fluoxetine Sensitive: D – Preclinical metformin + efavirenz + fluoxetine Sensitive : D	metformin + efavirenz + fluoxetine Sensitive: D – Preclinical metformin + efavirenz + fluoxetine Sensitive : D