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    DRUG:

    metformin

    Company:
    Generic mfg.
    Drug class:
    AMPK activator
    Related drugs:
    2d
    MCI: The Effects of Some Antihyperglycemic Drugs on Cognitive Function and Risk of Depression of Diabetic Patients (clinicaltrials.gov)
    P=N/A, N=300, Recruiting, Beni-Suef University | Trial completion date: Jan 2026 --> Dec 2026 | Trial primary completion date: Dec 2025 --> Jun 2026
    Trial completion date • Trial primary completion date
    |
    metformin
    2d
    BLC2001: An Efficacy and Safety Study of Erdafitinib (JNJ-42756493) in Participants With Urothelial Cancer (clinicaltrials.gov)
    P2, N=239, Active, not recruiting, Janssen Research & Development, LLC | Trial completion date: Dec 2026 --> Mar 2027
    Trial completion date
    |
    Balversa (erdafitinib) • metformin • midazolam hydrochloride
    3d
    Regulation of NRF2/HMOX-1/GPX4 Signaling Pathway by She Ethnic Medicine Shiliang Tea Inhibits Ferroptosis and Attenuates Non-alcoholic Fatty Liver Disease with Type 2 Diabetes Mellitus: Clinical Application and Mechanistic Study (ChiCTR2500115857)
    P=N/A, N=70, Not yet recruiting, Lishui People's Hospital; Lishui People's Hospital
    New trial
    |
    metformin
    3d
    Effects of Retagliptin Phosphate on BMD and bone metabolism markers in elderly female patients with type 2 diabetes mellitus (ChiCTR2500114555)
    P=N/A, N=86, Not yet recruiting, The Fifth Affiliated Hospital of Sun Yat-sen University; The Fifth Affiliated Hospital of Sun Yat-sen University
    New trial
    |
    metformin
    3d
    Efficacy of Daidzein Capsules Combined with Metformin in Metformin Low-Response Patients (ChiCTR2500112897)
    P=N/A, N=20, Recruiting, Jiangsu Province Hospital on Integration of Chinese and Western Medicine; Jiangsu Province Hospital on Integration of Chinese and Western Medicine
    New trial
    |
    metformin
    3d
    Clinical study on the regulation of diabetes by metformin combined with sugarcane polyphenols (ChiCTR2500111645)
    P=N/A, N=80, Not yet recruiting, Hebei Province Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine; Hebei Province Cangzhou Hospital of Integrated Traditional Ch
    New trial
    |
    metformin
    3d
    Clinical efficacy of iGlarLixi in patients with T2DM combined with MASLD (ChiCTR2500114461)
    P=N/A, N=25, Completed, Drum Tower Hospital Affiliated to Nanjing University Medical School; Drum Tower Hospital Affiliated to Nanjing University Medical School
    New trial
    |
    metformin
    3d
    Impact of metformin on thyroid function and autoimmune antibody in type 2 diabetic patients with Hashimoto's thyroiditis (ChiCTR2500113966)
    P=N/A, N=60, Completed, University-Town Hospital of Chongqing Medical University; University-Town Hospital of Chongqing Medical University
    New trial
    |
    metformin
    3d
    A comparative study of insulin combined with SGLT2 inhibitors/metformin in newly diagnosed type 2 diabetes patients (ChiCTR2600116249)
    P4, N=90, Not yet recruiting, Tianjin Medical University Chu Hsien-I Memorial Hospital; Tianjin Medical University Chu Hsien-I Memorial Hospital
    New P4 trial
    |
    metformin
    3d
    Clinical study on the effect of henagliflozin proline combined with metformin on serum markers of cognitive impairment related to type 2 diabetes (ChiCTR2500113390)
    P2, N=100, Not yet recruiting, Affiliated Hospital of Xuzhou Medical University, Xuzhou City, Jiangsu Province; Affiliated Hospital of Xuzhou Medical University
    New P2 trial
    |
    metformin
    3d
    Randomized, controlled and open label clinical trial of metformin Henagliflozin compound preparation in the treatment of type 2 diabetes mellitus patients with metabolic fatty liver disease and its effect on liver and pancreas fat content (ChiCTR2500108637)
    P4, N=60, Recruiting, The First People's Hospital of Foshan; The First People's Hospital of Foshan | Not yet recruiting --> Recruiting
    Enrollment open
    |
    metformin
    4d
    Metformin Hydrochloride and Doxycycline in Treating Patients With Head and Neck Squamous Cell Carcinoma (clinicaltrials.gov)
    P2, N=7, Terminated, Sidney Kimmel Cancer Center at Thomas Jefferson University | Active, not recruiting --> Terminated; Insufficient staff to conduct the trial
    Trial termination
    |
    metformin