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DRUG:

hydroxyureamethylacylfulvene (STAR-001)

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Company:

Lantern Pharma

Drug class:

Alkylating agent

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CASP6 overexpression	Non Small Cell Lung Cancer	CASP6 overexpression	Non Small Cell Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
HPGD underexpression	Non Small Cell Lung Cancer	HPGD underexpression	Non Small Cell Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
PTPRF underexpression	Non Small Cell Lung Cancer	PTPRF underexpression	Non Small Cell Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
KRT14 underexpression	Non Small Cell Lung Cancer	KRT14 underexpression	Non Small Cell Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
NAMPT overexpression	Non Small Cell Lung Cancer	NAMPT overexpression	Non Small Cell Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
SMARCD3 overexpression	Non Small Cell Lung Cancer	SMARCD3 overexpression	Non Small Cell Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
GLRX overexpression	Non Small Cell Lung Cancer	GLRX overexpression	Non Small Cell Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
KDM4A underexpression	Non Small Cell Lung Cancer	KDM4A underexpression	Non Small Cell Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
PTGR1 expression	Non Small Cell Lung Cancer	PTGR1 expression	Non Small Cell Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
PTGR1 elevation + HRD	Prostate Cancer	PTGR1 elevation + HRD	Prostate Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
PTGR1 elevation + HRD	Pancreatic Adenocarcinoma	PTGR1 elevation + HRD	Pancreatic Adenocarcinoma	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
PTGR1 elevation + HRD	Lung Adenocarcinoma	PTGR1 elevation + HRD	Lung Adenocarcinoma	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
ATM mutation	Lung Cancer	ATM mutation	Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
CHEK1 mutation	Lung Cancer	CHEK1 mutation	Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
BRCA1 mutation	Lung Cancer	BRCA1 mutation	Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D
STK11 mutation + KEAP1 mutation	Lung Cancer	STK11 mutation + KEAP1 mutation	Lung Cancer	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D	STAR-001 Sensitive: D – Preclinical STAR-001 Sensitive : D