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BIOMARKER:
BCL2 expression
i
Other names:
BCL2, Bcl-2, PPP1R50, B-cell CLL/lymphoma 2
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Entrez ID:
596
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
BCL2/BCL2L1 ratio elevation (3)
BCL2 rearrangement + MYC amplification (2)
BCL2/MCL1 ratio elevation (2)
BCL2 elevation + IGH elevation (1)
BCL2 fusion + EZH2 mutation (1)
Chr t(11;14) + BCL2 : BCL2L1 ratio elevation (1)
Chr t(11;14) + BCL2 overexpression (1)
MYC amplification + BCL2 amplification + TNFRSF8 expression (1)
PTEN deletion + BCL2 translocation (1)
BCL2/BAX ratio elevation (0)
BCL2/BCL2L1 ratio elevation (3)
BCL2 rearrangement + MYC amplification (2)
BCL2/MCL1 ratio elevation (2)
BCL2 elevation + IGH elevation (1)
BCL2 fusion + EZH2 mutation (1)
Chr t(11;14) + BCL2 : BCL2L1 ratio elevation (1)
Chr t(11;14) + BCL2 overexpression (1)
MYC amplification + BCL2 amplification + TNFRSF8 expression (1)
PTEN deletion + BCL2 translocation (1)
BCL2/BAX ratio elevation (0)
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BCL2 expression
Diffuse Large B Cell Lymphoma
BCL2 expression
Diffuse Large B Cell Lymphoma
venetoclax + obinutuzumab
Sensitive: C2 – Inclusion Criteria
venetoclax + obinutuzumab
Sensitive
:
C2
venetoclax + obinutuzumab
Sensitive: C2 – Inclusion Criteria
venetoclax + obinutuzumab
Sensitive
:
C2
BCL2 expression
Acute Myelogenous Leukemia
BCL2 expression
Acute Myelogenous Leukemia
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
BCL2 expression
Non-Hodgkin’s Lymphoma
BCL2 expression
Non-Hodgkin’s Lymphoma
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
BCL2 expression
Diffuse Large B Cell Lymphoma
BCL2 expression
Diffuse Large B Cell Lymphoma
lenalidomide
Sensitive: C2 – Inclusion Criteria
lenalidomide
Sensitive
:
C2
lenalidomide
Sensitive: C2 – Inclusion Criteria
lenalidomide
Sensitive
:
C2
BCL2 expression
Hodgkin Lymphoma
BCL2 expression
Hodgkin Lymphoma
Resistant: C3 – Early Trials
Resistant
:
C3
Resistant: C3 – Early Trials
Resistant
:
C3
BCL2 expression
Hodgkin Lymphoma
BCL2 expression
Hodgkin Lymphoma
venetoclax
Sensitive: D – Preclinical
venetoclax
Sensitive
:
D
venetoclax
Sensitive: D – Preclinical
venetoclax
Sensitive
:
D
BCL2 expression
Diffuse Large B Cell Lymphoma
BCL2 expression
Diffuse Large B Cell Lymphoma
venetoclax + S63845
Sensitive: D – Preclinical
venetoclax + S63845
Sensitive
:
D
venetoclax + S63845
Sensitive: D – Preclinical
venetoclax + S63845
Sensitive
:
D
BCL2 expression
Diffuse Large B Cell Lymphoma
BCL2 expression
Diffuse Large B Cell Lymphoma
S63845
Resistant: D – Preclinical
S63845
Resistant
:
D
S63845
Resistant: D – Preclinical
S63845
Resistant
:
D
BCL2 expression
Multiple Myeloma
BCL2 expression
Multiple Myeloma
S63845
Sensitive: D – Preclinical
S63845
Sensitive
:
D
S63845
Sensitive: D – Preclinical
S63845
Sensitive
:
D
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