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BIOMARKER:
BCL2 expression
i
Other names:
BCL2, Bcl-2, PPP1R50, B-cell CLL/lymphoma 2
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Entrez ID:
596
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
BCL2 overexpression (17)
BCL2 expression + MYC expression (8)
BCL2 positive (7)
MYC overexpression + BCL2 overexpression (7)
BCL2 overexpression + MCL1 overexpression (2)
BCL2 underexpression (2)
MYC expression + BCL2 expression (2)
BCL2 overexpression + CCND1 overexpression (1)
BCL2 overexpression + MCL1 expression (1)
BCL2 overexpression + MCL1 underxpression + BCL2L1 underexpression (1)
BCL2 overexpression + MYC overexpression (1)
BCL2 positive + LGALS3 expression (1)
BTK expression + BCL2 expression (1)
BTK expression + BCL2 expression + MYC expression (1)
CASP3 overexpression + BCL2 negative (1)
CASP3 underexpression + BCL2 positive (1)
CD20 expression + PAX5 expression + BCL2 expression (1)
CD22 underexpression + BCL2 overexpression (1)
MYC expression + BCL2 expression + BCL6 expression (1)
MYC positive + BCL2 positive (1)
MYC positive + BCL2 positive + BCL6 positive (1)
BCL2 positive + IGH positive (0)
BCL2 overexpression (17)
BCL2 expression + MYC expression (8)
BCL2 positive (7)
MYC overexpression + BCL2 overexpression (7)
BCL2 overexpression + MCL1 overexpression (2)
BCL2 underexpression (2)
MYC expression + BCL2 expression (2)
BCL2 overexpression + CCND1 overexpression (1)
BCL2 overexpression + MCL1 expression (1)
BCL2 overexpression + MCL1 underxpression + BCL2L1 underexpression (1)
BCL2 overexpression + MYC overexpression (1)
BCL2 positive + LGALS3 expression (1)
BTK expression + BCL2 expression (1)
BTK expression + BCL2 expression + MYC expression (1)
CASP3 overexpression + BCL2 negative (1)
CASP3 underexpression + BCL2 positive (1)
CD20 expression + PAX5 expression + BCL2 expression (1)
CD22 underexpression + BCL2 overexpression (1)
MYC expression + BCL2 expression + BCL6 expression (1)
MYC positive + BCL2 positive (1)
MYC positive + BCL2 positive + BCL6 positive (1)
BCL2 positive + IGH positive (0)
›
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VERI cancer hierarchy
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BCL2 expression
Diffuse Large B Cell Lymphoma
BCL2 expression
Diffuse Large B Cell Lymphoma
venetoclax + obinutuzumab
Sensitive: C2 – Inclusion Criteria
venetoclax + obinutuzumab
Sensitive
:
C2
venetoclax + obinutuzumab
Sensitive: C2 – Inclusion Criteria
venetoclax + obinutuzumab
Sensitive
:
C2
BCL2 expression
Acute Myelogenous Leukemia
BCL2 expression
Acute Myelogenous Leukemia
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
BCL2 expression
Non-Hodgkin’s Lymphoma
BCL2 expression
Non-Hodgkin’s Lymphoma
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
BCL2 expression
Diffuse Large B Cell Lymphoma
BCL2 expression
Diffuse Large B Cell Lymphoma
lenalidomide
Sensitive: C2 – Inclusion Criteria
lenalidomide
Sensitive
:
C2
lenalidomide
Sensitive: C2 – Inclusion Criteria
lenalidomide
Sensitive
:
C2
BCL2 expression
Hodgkin Lymphoma
BCL2 expression
Hodgkin Lymphoma
Resistant: C3 – Early Trials
Resistant
:
C3
Resistant: C3 – Early Trials
Resistant
:
C3
BCL2 expression
Hodgkin Lymphoma
BCL2 expression
Hodgkin Lymphoma
venetoclax
Sensitive: D – Preclinical
venetoclax
Sensitive
:
D
venetoclax
Sensitive: D – Preclinical
venetoclax
Sensitive
:
D
BCL2 expression
Diffuse Large B Cell Lymphoma
BCL2 expression
Diffuse Large B Cell Lymphoma
venetoclax + S63845
Sensitive: D – Preclinical
venetoclax + S63845
Sensitive
:
D
venetoclax + S63845
Sensitive: D – Preclinical
venetoclax + S63845
Sensitive
:
D
BCL2 expression
Diffuse Large B Cell Lymphoma
BCL2 expression
Diffuse Large B Cell Lymphoma
S63845
Resistant: D – Preclinical
S63845
Resistant
:
D
S63845
Resistant: D – Preclinical
S63845
Resistant
:
D
BCL2 expression
Multiple Myeloma
BCL2 expression
Multiple Myeloma
S63845
Sensitive: D – Preclinical
S63845
Sensitive
:
D
S63845
Sensitive: D – Preclinical
S63845
Sensitive
:
D
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