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BIOMARKER:
BCL2 expression
i
Other names:
BCL2, Bcl-2, PPP1R50, B-cell CLL/lymphoma 2
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Entrez ID:
596
Related biomarkers:
Expression
Mutation
CNA
Fusion
Others
‹
MYC rearrangement + BCL2 rearrangement (22)
BCL2 mutation (6)
MYC rearrangement + BCL2 rearrangement + BCL6 rearrangement (6)
BCL2 G101V (4)
BCL2 rearrangement (3)
MYC translocation + BCL2 translocation (3)
BCL2 D103Y (2)
BCL2 F104I (1)
BCL2 G101V + SF3B1 mutation (1)
BCL2 N103E (1)
BCL2 N103Y (1)
BCL2 N107_N110dup (1)
BCL2 V156N (1)
EZH2 mutation + BCL2 translocation (1)
MYC translocation + BCL6 translocation + BCL2 translocation (1)
TP53 mutation + BCL2 rearrangement (1)
BCL2 translocation (0)
MYC rearrangement + BCL2 rearrangement+ BCL6 rearrangement (0)
MYC rearrangement + BCL2 rearrangement (22)
BCL2 mutation (6)
MYC rearrangement + BCL2 rearrangement + BCL6 rearrangement (6)
BCL2 G101V (4)
BCL2 rearrangement (3)
MYC translocation + BCL2 translocation (3)
BCL2 D103Y (2)
BCL2 F104I (1)
BCL2 G101V + SF3B1 mutation (1)
BCL2 N103E (1)
BCL2 N103Y (1)
BCL2 N107_N110dup (1)
BCL2 V156N (1)
EZH2 mutation + BCL2 translocation (1)
MYC translocation + BCL6 translocation + BCL2 translocation (1)
TP53 mutation + BCL2 rearrangement (1)
BCL2 translocation (0)
MYC rearrangement + BCL2 rearrangement+ BCL6 rearrangement (0)
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BCL2 expression
Diffuse Large B Cell Lymphoma
BCL2 expression
Diffuse Large B Cell Lymphoma
venetoclax + obinutuzumab
Sensitive: C2 – Inclusion Criteria
venetoclax + obinutuzumab
Sensitive
:
C2
venetoclax + obinutuzumab
Sensitive: C2 – Inclusion Criteria
venetoclax + obinutuzumab
Sensitive
:
C2
BCL2 expression
Acute Myelogenous Leukemia
BCL2 expression
Acute Myelogenous Leukemia
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
BCL2 expression
Non-Hodgkin’s Lymphoma
BCL2 expression
Non-Hodgkin’s Lymphoma
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
venetoclax
Sensitive: C2 – Inclusion Criteria
venetoclax
Sensitive
:
C2
BCL2 expression
Diffuse Large B Cell Lymphoma
BCL2 expression
Diffuse Large B Cell Lymphoma
lenalidomide
Sensitive: C2 – Inclusion Criteria
lenalidomide
Sensitive
:
C2
lenalidomide
Sensitive: C2 – Inclusion Criteria
lenalidomide
Sensitive
:
C2
BCL2 expression
Hodgkin Lymphoma
BCL2 expression
Hodgkin Lymphoma
Resistant: C3 – Early Trials
Resistant
:
C3
Resistant: C3 – Early Trials
Resistant
:
C3
BCL2 expression
Hodgkin Lymphoma
BCL2 expression
Hodgkin Lymphoma
venetoclax
Sensitive: D – Preclinical
venetoclax
Sensitive
:
D
venetoclax
Sensitive: D – Preclinical
venetoclax
Sensitive
:
D
BCL2 expression
Diffuse Large B Cell Lymphoma
BCL2 expression
Diffuse Large B Cell Lymphoma
venetoclax + S63845
Sensitive: D – Preclinical
venetoclax + S63845
Sensitive
:
D
venetoclax + S63845
Sensitive: D – Preclinical
venetoclax + S63845
Sensitive
:
D
BCL2 expression
Diffuse Large B Cell Lymphoma
BCL2 expression
Diffuse Large B Cell Lymphoma
S63845
Resistant: D – Preclinical
S63845
Resistant
:
D
S63845
Resistant: D – Preclinical
S63845
Resistant
:
D
BCL2 expression
Multiple Myeloma
BCL2 expression
Multiple Myeloma
S63845
Sensitive: D – Preclinical
S63845
Sensitive
:
D
S63845
Sensitive: D – Preclinical
S63845
Sensitive
:
D
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